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Journal cover: Molecular BioSystems

Molecular BioSystems

Research at the interface of chemistry and biology: chemical biology, -omics sciences and systems biology.
Impact Factor 2.829 12 Issues per Year Indexed in Medline
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Molecular BioSystems,
01 July 2016 , Issue 7,
Page 2013 to 2306
A. Marco-Ramell, A. M. de Almeida, S. Cristobal, P. Rodrigues, P. Roncada and A. Bassols
Mol. BioSyst., 2016, 12, 2024-2035
DOI: 10.1039/C5MB00788G, Review Article
From themed collection Omics in Animal Sciences
Stress and welfare are important factors in animal production in the context of growing production optimization and scrutiny by the general public.
N. Guillemin, A. Horvatić, J. Kuleš, A. Galan, Vladimir Mrljak and M. Bhide
Mol. BioSyst., 2016, 12, 2036-2046
DOI: 10.1039/C6MB00220J, Review Article
From themed collection Omics in Animal Sciences
Disease pathways can be explained into a list of biomarkers at different scales to develop applications.
Louis Papageorgiou, Nguyen Tien Cuong and Dimitrios Vlachakis
Mol. BioSyst., 2016, 12, 2047-2055
DOI: 10.1039/C5MB00699F, Review Article
From themed collection Omics in Animal Sciences
Antibodies have been in the frontline of anticancer research during the last few decades, since a number of different ways have been discovered to utilize them as parts or main components of anticancer drugs.
Mol. BioSyst., 2016, 12, 2056-2063
DOI: 10.1039/C5MB00890E, Review Article
From themed collection Omics in Animal Sciences
This review will give an overview of immune relevant molecules in fish skin mucus.
C. A. Bader, E. A. Carter, A. Safitri, P. V. Simpson, P. Wright, S. Stagni, M. Massi, P. A. Lay, D. A. Brooks and S. E. Plush
Mol. BioSyst., 2016, 12, 2064-2068
DOI: 10.1039/C6MB00242K, Communication
From themed collection Chemical Biology in Molecular BioSystems
Localisation of a neutral rhenium(I) tricarbonyl phenanthroline species to regions of high polar lipid concentrations is demonstrated by Fourier transform infrared (FTIR) microspectroscopy.
V. Pirro, S. C. Guffey, M. S. Sepúlveda, C. T. Mahapatra, C. R. Ferreira, A. K. Jarmusch and R. G. Cooks
Mol. BioSyst., 2016, 12, 2069-2079
DOI: 10.1039/C6MB00168H, Paper
Spatial maps of lipid profiles in intact zebrafish embryos and a description of variation through early development.
Mol. BioSyst., 2016, 12, 2080-2093
DOI: 10.1039/C5MB00706B, Paper
From themed collection Omics in Animal Sciences
The rate of Flaviviridae family virus infections worldwide has increased dramatically in the last few years.
Mariana Palma, Lorenzo E. Hernández-Castellano, Noemí Castro, Anastasio Arguëllo, Juan Capote, Manolis Matzapetakis and André Martinho de Almeida
Mol. BioSyst., 2016, 12, 2094-2107
DOI: 10.1039/C5MB00851D, Paper
From themed collection Omics in Animal Sciences
Goats are of special importance in the Mediterranean and tropical regions for producing a variety of dairy products.
Mol. BioSyst., 2016, 12, 2108-2118
DOI: 10.1039/C6MB00111D, Paper
From themed collection Chemical Biology in Molecular BioSystems
Family with sequence similarity 20, member C (Fam20C) is a physiological Golgi casein kinase that phosphorylates multiple secreted proteins.
Mol. BioSyst., 2016, 12, 2119-2134
DOI: 10.1039/C6MB00210B, Paper
From themed collection 2016 Hot Articles in Molecular BioSystems
Analysis of protein–protein interaction networks of CYP proteins of human, mouse and rat gives insights about functionality and species differences.
Feng Li, Lin Gao, Xiaoke Ma and Xiaofei Yang
Mol. BioSyst., 2016, 12, 2135-2141
DOI: 10.1039/C6MB00084C, Paper
From themed collection 2016 Hot Articles in Molecular BioSystems
A mutated gene network is constructed based on a new mutual exclusivity index and coverage for detecting driver pathways.
Giulia Sormani, Jan O. Haerter, Cecilia Lövkvist and Kim Sneppen
Mol. BioSyst., 2016, 12, 2142-2146
DOI: 10.1039/C6MB00044D, Paper
From themed collection 2016 Hot Articles in Molecular BioSystems
DNA methylation at CpG sites is an epigenetic mark that correlates with gene expresssion. Dense regions of CpG sites, so-called CpG islands, are often either fully methylated or fully unmethylated, hinting at a bistable dynamical process by which sites undergo coordinated methylation activity. We here explore a process by which CpG sites can protect others from becoming methylated, thereby re-enforcing the bistable dynamics.
Silvia Grigolon, Silvio Franz and Matteo Marsili
Mol. BioSyst., 2016, 12, 2147-2158
DOI: 10.1039/C6MB00047A, Paper
Evolution in its course has found a variety of solutions to the same optimisation problem.
Mol. BioSyst., 2016, 12, 2159-2167
DOI: 10.1039/C6MB00158K, Paper
In silico methods and experimental data obtained from fluorescence studies allowed the identification of a new binding pocket for the HER2-DIVMP receptor model.
Cristiano Spadaccio, Raffaella Coccia, Marzia Perluigi, Gilda Pupo, Maria Eugenia Schininà, Alessandra Giorgi, Carla Blarzino, Francesco Nappi, Fraser W. Sutherland, Massimo Chello and Fabio Di Domenico
Mol. BioSyst., 2016, 12, 2168-2177
DOI: 10.1039/C6MB00152A, Paper
Oxidative stress is undoubtedly one of the main players in abdominal aortic aneurysm (AAA) pathophysiology.
Mol. BioSyst., 2016, 12, 2178-2188
DOI: 10.1039/C6MB00225K, Paper
A potential lead compound to overcome dapsone resistance in M. leprae folP1 was identified by a virtual screening strategy.
Hadi Farsiani, Arman Mosavat, Saman Soleimanpour, Hamid Sadeghian, Mohammad Reza Akbari Eydgahi, Kiarash Ghazvini, Mojtaba Sankian, Ehsan Aryan, Saeid Amel Jamehdar and Seyed Abdolrahim Rezaee
Mol. BioSyst., 2016, 12, 2189-2201
DOI: 10.1039/C6MB00174B, Paper
From themed collection Chemical Biology in Molecular BioSystems
Tuberculosis (TB) remains a major global health threat despite chemotherapy and Bacilli Calmette–Guérin (BCG) vaccination.
Wei Miaomiao, Liu Chunhua, Zhang Xiaochen, Chen Xiaoniao, Lin Hongli and Yang Zhuo
Mol. BioSyst., 2016, 12, 2202-2212
DOI: 10.1039/C6MB00195E, Paper
From themed collection Chemical Biology in Molecular BioSystems
Podocytes are the major sites of vascular endothelial growth factor (VEGF) production in kidneys.
Xingxing Wang, Dian Wang, Xiaojun Yu, Guohong Zhang, Jiayan Wu, Guanghui Zhu, Ruibing Su and Junyao Lv
Mol. BioSyst., 2016, 12, 2213-2223
DOI: 10.1039/C6MB00080K, Paper
Lethal ventricular tachyarrhythmia (LVTA) is the predominant underlying mechanism of sudden cardiac death (SCD).
Mol. BioSyst., 2016, 12, 2224-2232
DOI: 10.1039/C6MB00049E, Paper
From themed collection Chemical Biology in Molecular BioSystems
Recently, accumulating studies have indicated that microRNAs (miRNAs) play an important role in exploring the pathogenesis of various human diseases at the molecular level and may result in the design of specific tools for diagnosis, treatment evaluation and prevention.
Mol. BioSyst., 2016, 12, 2233-2246
DOI: 10.1039/C6MB00189K, Paper
From themed collection Chemical Biology in Molecular BioSystems
Structural knowledge of substrate recognition by SKP1–CUL1–βTrCP1 complex for targeted cancer therapeutic strategy.
Natalya A. Torgasheva, Natalya I. Menzorova, Yurii T. Sibirtsev, Valery A. Rasskazov, Dmitry O. Zharkov and Georgy A. Nevinsky
Mol. BioSyst., 2016, 12, 2247-2256
DOI: 10.1039/C5MB00906E, Paper
From themed collection Chemical Biology in Molecular BioSystems
We have characterized the profile of several key base excision repair activities in the developing embryo of the grey sea urchin, Strongylocentrotus intermedius, at several stages of development.
Mol. BioSyst., 2016, 12, 2257-2264
DOI: 10.1039/C6MB00108D, Paper
Nicotinamide exerts a protective effect on cardiomyoblasts against hypoxia/re-oxygenation-induced injury through reduction of reactive oxygen species generation via succinate dehydrogenase inhibition.
Huanhuan Qi, Jun Bao, Guohua An, Gang Ouyang, Pengling Zhang, Chao Wang, Hanjie Ying, Pingkai Ouyang, Bo Ma and Qi Zhang
Mol. BioSyst., 2016, 12, 2265-2275
DOI: 10.1039/C6MB00181E, Paper
The present study describes for the first time, a metabolic profile reflecting the osteoporosis progression in 364 pre- and postmenopausal Chinese women using GC-MS.
Mol. BioSyst., 2016, 12, 2276-2287
DOI: 10.1039/C6MB00182C, Paper
From themed collection Chemical Biology in Molecular BioSystems
Arginine to histidine mutation at position 132 (R132H) in isocitrate dehydrogenase 1 (IDH1) led to reduced affinity of the respective enzymes for isocitrate and increased affinity for α-ketoglutarate (AKG) and NADPH.

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