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Journal cover: Molecular BioSystems

Molecular BioSystems

Research at the interface of chemistry and biology: chemical biology, -omics sciences and systems biology.
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Molecular BioSystems,
01 April 2017 , Issue 4,
Page 623 to 806
Mol. BioSyst., 2017, 13, 632-632
DOI: 10.1039/C7MB90013A, Editorial
We would like to take this opportunity to highlight the Outstanding Reviewers for Molecular BioSystems in 2016, as selected by the editorial team for their significant contribution to the journal.
Mol. BioSyst., 2017, 13, 633-637
DOI: 10.1039/C7MB00065K, Opinion
We propose that the Ca2+-ATPase pump forms pores that facilitate bidirectional proton transport across the sarco/endoplasmic reticulum.
Mol. BioSyst., 2017, 13, 638-647
DOI: 10.1039/C6MB00866F, Review Article
From themed collection 2017 Hot Articles in Molecular Biosystems
This review highlights recent screening methods for identifying pharmacological chaperones, which are small-molecules capable of rescuing misfolded proteins.
Katelyn R. Ludwig and Amanda B. Hummon
Mol. BioSyst., 2017, 13, 648-664
DOI: 10.1039/C6MB00656F, Review Article
Sepsis is a serious medical condition that occurs in 30% of patients in intensive care units (ICUs).
Mol. BioSyst., 2017, 13, 665-676
DOI: 10.1039/C6MB00789A, Review Article
Consensus of the architecture and composition of the elements that form transcriptional units in E. coli and comparison with synthetic genetic circuits.
Anil K. Gorle, Amy L. Bottomley, Elizabeth J. Harry, J. Grant Collins, F. Richard Keene and Clifford E. Woodward
Mol. BioSyst., 2017, 13, 677-680
DOI: 10.1039/C6MB00753H, Communication
From themed collection 2017 Hot Articles in Molecular Biosystems
Fluorescence microscopy has been used to examine the condensation of DNA in live bacteria by a tetranuclear polypyridylruthenium(II) complex.
Venkatesh Vaidyanathan, Vijay Naidu, Chi Hsiu-Juei Kao, Nishi Karunasinghe, Karen S. Bishop, Alice Wang, Radha Pallati, Phillip Shepherd, Jonathan Masters, Shuotun Zhu, Megan Goudie, Mohanraj Krishnan, Anower Jabed, Gareth Marlow, Ajit Narayanan and Lynnette R. Ferguson
Mol. BioSyst., 2017, 13, 681-698
DOI: 10.1039/C6MB00873A, Paper
From themed collection 2017 Hot Articles in Molecular Biosystems
Genes with SNPs that were significantly associated with risk for aggressive and non-aggressive prostate cancer were identified.
Navid Nezafat, Mahboobeh Eslami, Manica Negahdaripour, Mohammad Reza Rahbar and Younes Ghasemi
Mol. BioSyst., 2017, 13, 699-713
DOI: 10.1039/C6MB00772D, Paper
In this study, we have applied bioinformatics approaches to design potential vaccine target for oral immunization against Helicobacter pylori.
Mol. BioSyst., 2017, 13, 714-724
DOI: 10.1039/C6MB00692B, Paper
Cardiac hypertrophy is a complex process involving highly coordinated but tight regulation of multiple elements, such as in epigenetics, which make an important contribution to myocardium remodeling and cardiac hypertrophy.
Sadegh Sulaimany, Mohammad Khansari, Peyman Zarrineh, Madelaine Daianu, Neda Jahanshad, Paul M. Thompson and Ali Masoudi-Nejad
Mol. BioSyst., 2017, 13, 725-735
DOI: 10.1039/C6MB00815A, Paper
Assessment of the predictability power of link prediction algorithms in their basic form for brain network changes during Alzheimer's disease.
Mol. BioSyst., 2017, 13, 736-749
DOI: 10.1039/C6MB00638H, Paper
The binding of TTR with sulfated-PBDEs and OH-PBDEs shows different molecular recognition mechanisms.
Mol. BioSyst., 2017, 13, 750-755
DOI: 10.1039/C6MB00796A, Paper
A first report on the biosynthetic origin of Mycobacterium tuberculosis specific small volatile molecules.
Mingxiao Zhao, Kim KT Lau, Xian Zhou, Jianfang Wu, Jun Yang and Chang Wang
Mol. BioSyst., 2017, 13, 756-766
DOI: 10.1039/C6MB00785F, Paper
Non-linear KPLS score plot based on the panel of potential biomarkers for radiation exposure.
Mol. BioSyst., 2017, 13, 767-774
DOI: 10.1039/C7MB00054E, Paper
Enhancers are cis-acting elements that play major roles in upregulating eukaryotic gene expression by providing binding sites for transcription factors and their complexes.
Mol. BioSyst., 2017, 13, 775-784
DOI: 10.1039/C7MB00052A, Paper
We show that steady state cross-moments and cross-cumulants predict bistability in feedback-regulated reaction networks.
Mol. BioSyst., 2017, 13, 785-795
DOI: 10.1039/C6MB00860G, Paper
An efficient multi-label protein subcellular localization prediction system was developed by introducing multiple kernel learning (MKL) based support vector machine (SVM).
R. G. Brajesh, Nikhil Raj and Supreet Saini
Mol. BioSyst., 2017, 13, 796-803
DOI: 10.1039/C6MB00765A, Paper
How does a transcription network arrive at the particular values of biochemical interactions defining it?

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58 citations
With the avalanche of DNA/RNA sequences generated in the post-genomic age, it is urgent to develop automated methods for analyzing the relationship between the sequences and their functions.
DOI: 10.1039/C5MB00155B
Published: 05 Jun 2015
18 citations
Immunoglobulins, also called antibodies, are a group of cell surface proteins which are produced by the immune system in response to the presence of a foreign substance (called antigen).
DOI: 10.1039/C5MB00883B
Published: 11 Feb 2016
15 citations
ReactomePA is an R package providing functional analyses at the gene and sequence levels, with several visualization functions provided.
DOI: 10.1039/C5MB00663E
Published: 23 Nov 2015

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