Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
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Jeremy E. Schonhorn, Syrena C. Fernandes, Anjali Rajaratnam, Rachel N. Deraney, Jason P. Rolland and Charles R. Mace
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00876F, Paper
Diagnostic assays can provide valuable information about the health status of a patient, which include detection of biomarkers that indicate the presence of an infection, the progression or regression of...
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00892H, Paper
We report a new proof-of-concept bubble-based gas sensor for a gas chromatography system, which utilizes the unique relationship between the diameters of the produced bubbles to the gas types and...
Carl Grenvall, Christian Antfolk, Christer Zoffmann Bisgaard and Thomas Laurell
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00982G, Paper
The field of cytometry has grown in scope and importance ever since the early 20th century with leaps in technology introducing the Coulter counter and the flow cytometer. Cytometry methods...
Mais J. Jebrail, Ron Renzi, Anupama Sinha, Jim Van De Vreugde, Carmen Gondhalekar, Cesar Ambriz, Robert J Meagher and Steven S Branda
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00703D, Paper
Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications. In many cases, it is desirable to carry out...
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01031K, Paper
Clean and sustainable energy generation from ambient environment is important not only for large scale systems but also for tiny electrical devices because of the limitation of batteries or external...
Minsoung Rhee, Yooli K. Light, Suzan Yilmaz, Paul D. Adams, Deepak Saxena, Robert J. Meagher and Anup K. Singh
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00823E, Paper
Our novel pressure balancing structure stabilizes a picoinjector, allowing reagent injection into flowing droplets in channels with fluctuating pressure.
Siwei Li, Peter Glynne-Jones, Orestis G. Andriotis, Kuan Y. Ching, Umesh S. Jonnalagadda, Richard O. C. Oreffo, Martyn Hill and Rahul S. Tare
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00956H, Paper
Bioengineering neocartilage grafts of human articular chondrocytes in a custom-built microfluidic perfusion bioreactor with integrated ultrasound standing wave trap.
Hardik J. Pandya, Wenjin Chen, Lauri A. Goodell, David J. Foran and Jaydev P. Desai
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00594E, Paper
The mechanical properties of tissue change significantly during the progression from healthy to malignant.
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01014K, Paper
This paper discusses a novel, simple, and inexpensive micro-volume ultrafiltration technique for protein concentration, desalting, buffer exchange, and size-based protein purification. The technique is suitable for processing protein samples in...
Collin Lawrence Sones, Ioannis Katis, Peijun J. W. He, Ben Mills, Medya Fouad Namiq, Peter Shardlow, Morten Ibsen and Robert W Eason
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00850B, Paper
Paper-based microfluidics is a rapidly progressing inter-disciplinary technology driven by the need for low-cost alternatives to conventional point-of-care diagnostic tools. For transport of reagents/analytes, such devices often consist of interconnected...
E. Ortiz-Ortega, Marc-Antoni Goulet, Jin Wook Lee, M Guerra-Balcázar, Noé Arjona, Erik Kjeang, J. Ledesma-García and L. G. Arriaga
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01010H, Communication
The use of three-dimensional flow-through nanoporous electrodes was explored and successfully applied in a formic acid air-breathing nanofluidic fuel cell. The effects of fuel concentration, reaction stoichiometry and catalyst mass...
Ghulam Destgeer, Byung Hang Ha, Jin Ho Jung and Hyung Jin Sung
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00868E, Paper
Submicron separation is the segregation of the particles having diameter difference of less than one micrometre. We present an acoustofluidic particle separator with submicron separation resolution to study the continuous,...
JiSoo Park, Bo Kyeong Lee, Gi Seok Jeong, Jung Keun Hyun, Changjoon Justin Lee and Sang-Hoon Lee
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00962B, Paper
There has been a growing need for in vitro models of neurodegenerative diseases such as Alzheimer’s disease that would enable a better understanding of etiology and faster development of treatment...
Raffaella Molteni, Elena Bianchi, Paolo Patete, Monica Fabbri, Guido Baroni, Gabriele Dubini and Ruggero Pardi
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00741G, Paper
Leukocyte extravasation and interstitial migration are key events during inflammation. Traditional in vitro techniques address only specific steps of cell recruitment to tissues and fail to recapitulate the whole process...
Gui-Ping Zhu, Majid Hejazian, Xiaoyang Huang and Nam-Trung Nguyen
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00885E, Paper
Magnetic manipulation is a promising technique for lab-on-a-chip platforms. The magnetic approach can avoid problems associated with heat, surface charge, ionic concentration and pH level. The present paper investigates the...
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00869C, Paper
In recent years there has been great progress harnessing the small-feature size and programmability of integrated circuits (ICs) for biological applications, by building microfluidics directly on top of ICs. However,...
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00990H, Paper
The molecular stretching of DNA is an indispensable tool for the optical exploration of base sequences and epigenomic changes of DNA at a single molecule level. In stretching terminal-unmodified DNA...
Hyewon Lee, Shin Ae Kim, Sean Coakley, Paula Mugno, Marc Hammarlund, Massimo A. Hilliard and Hang Lu
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00789A, Paper
We present a high-density microfluidic device for target-selective illumination, selective stimulation, and long-term monitoring of C. elegans.
Alvaro J. Conde, Milena Batalla, Belén Cerda, Olga Mykhaylyk, Christian Plank, Osvaldo Podhajcer, Juan M. Cabaleiro, Rossana E. Madrid and Lucia Policastro
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00839A, Paper
A low-cost, portable microfluidic platform for preparing monodisperse magnetoliposomal suspensions that does not require extrusion steps.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00734D, Paper
We present a novel paper-based analytical device for isotachophoretic sample focusing, enabling processing of a 30 μL sample and a 1000-fold increase in peak concentration in several minutes.
Nicolas C. Pégard, Marton L. Toth, Monica Driscoll and Jason W. Fleischer
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00701H, Communication
From themed collection Lab on a Chip 2014 HOT Articles
We present a 3D tomography technique for in vivo observation of microscopic samples.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00785A, Paper
This paper describes the development of a new, easy-to-implement approach to generate high-throughput microfluidic particle-separation devices.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00895B, Technical Innovation
We applied a simple evaporation-based self-assembly technique to create a sub-50 nm nanofluidic junction between two microchannels in PDMS.
Yuliang Zhao, Hok Sum Sam Lai, Guanglie Zhang, Gwo-Bin Lee and Wen Jung Li
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00795F, Paper
Single-cell density and mass were measured rapidly using a combination of optically induced electrokinetics, microfluidics, computer vision, and classical sedimentation theory.
Zhuoqing Yang, Yi Zhang, Toshihiro Itoh and Ryutaro Maeda
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00997E, Technical Innovation
We present a novel lab-on-a-tube technology, which is a combination of three-dimensional (3D) cylindrical photolithography and nanoimprint process, for fabricating micro functional structures on tiny tube substrate directly. As example,...

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