Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.67 24 Issues per Year Indexed in MEDLINE
 
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Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50522G, Perspective
The historical background of microfluidics research within Canada is discussed from the personal perspective of the author, D. Jed Harrison.
 
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50501D, Paper
The integration of color filters with microfluidics has attracted substantial attention in recent years, for on-chip absorption, fluorescence, or Raman analysis. We describe such tunable filters based on the micro-flow...
 
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50427A, Paper
This paper describes a microfluidic system and a technique for electrically measuring the deformability of red blood cells (RBCs). RBCs are deformed when they flow through a small capillary (microfluidic...
 
Wen-I. Wu, Niels Rochow, Emily Chan, Gerhard Fusch, Asmaa Manan, Dipen Nagpal, P. Ravi. Selvaganapathy and Christoph Fusch
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC41417E, Paper
This paper reports the development of microfluidic oxygenator (MFO) units designed for a lung assist device (LAD) for newborn infants.
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50300C, Paper
We present a platform capable of immobilizing only the body and not the head of C. elegans for dynamic imaging applications while allowing feeding.
 
Andries D. van der Meer, Valeria V. Orlova, Peter ten Dijke, Albert van den Berg and Christine L. Mummery
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50435B, Paper
We describe a microfluidic, three-dimensional model of a blood vessel. We analyze the structural organization and the three-dimensional interaction between human primary endothelial cells and human pluripotent stem cell-derived pericytes.
 
Chien-Chung Peng, Wei-Hao Liao, Ying-Hua Chen, Chueh-Yu Wu and Yi-Chung Tung
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50388G, Paper
Oxygen tension plays an important role in regulating various cellular functions in both normal physiology and disease states. Therefore, drug testing using conventional in vitro cell models under normoxia often...
 
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50370D, Paper
A new on-chip whole blood/plasma separator driven by asymmetric capillary forces, which are produced through a microchannel with sprayed nanobead multilayers, has been designed, fabricated and fully characterized for the...
 
Nicolas Descharmes, Ulagalandha Perumal Dharanipathy, Zhaolu Diao, Mario Tonin and Romuald Houdré
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50447F, Paper
We demonstrate a resonant optical trapping mechanism based on two-dimensional hollow photonic crystal cavities. This approach benefits simultaneously from the resonant nature and unprecedented field overlap with the trapped specimen....
 
Nasim Annabi, Hojae Bae, Mehmet R. Dokmeci and Ali Khademhosseini
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC90047A, Highlight
A perfusable vascular network–A gradient generator microfluidic chip–Storing data on a microfluidic chip.
 
Utkur Mirsaidov, V. R. S. S. Mokkapati, Dipanjan Bhattacharya, Henrik Andersen, Michel Bosman, Barbaros Özyilmaz and Paul Matsudaira
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50304F, Communication
The interaction of a bubble and a nanoparticle in graphene nanochannels.
 
Martina Viefhues, Sonja Wegener, Anja Rischmüller, Martin Schleef and Dario Anselmetti
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50475A, Paper
We present a prototype nanofluidic device, developed for the continuous-flow dielectrophoretic (DEP) fractionation, purification, and quality control of sample suspensions as for gene vaccine production. The device consists of a...
 
Mingjian Shi, Devi Majumdar, Yandong Gao, Bryson Brewer, Cody Goodwin, John A McLean, Deyu Li and Donna J. Webb
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50249J, Paper
Two novel microfluidic cell culture schemes, a vertically-layered set-up and a four chamber set-up, were developed for co-culturing central nervous system (CNS) neurons and glia. The cell chambers in these...
 
Emeline Descamps, Nathalie Duroure, Frédérique Deiss, Thierry Leichlé, Catherine Adam, Pascal Mailley, Ali Aït-Ikhlef, Thierry Livache, Liviu Nicu and Neso Sojic
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50335F, Paper
Optical nanotip arrays fabricated on etched fiber bundles were functionalized with DNA spots.
 
Peter B. Lillehoj, Ming-Chun Huang, Newton Truong and Chih-Ming Ho
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50306B, Paper
We describe an innovative mobile phone platform for rapid, quantitative biomolecular detection.
 
Adam Williamson, Sukhdeep Singh, Uta Fernekorn and Andreas Schober
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50237F, Critical Review
As significant advancements in technology focused on Organ-on-a-chip continue, it is feasible to consider the future of Body-on-a-chip technology.
 
Mehmet Cagatay Tarhan, Yslam Orazov, Ryuji Yokokawa, Stanislav L. Karsten and Hiroyuki Fujita
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50151E, Paper
The concept of reconstructed microtubule kinesin-based transport system was originally introduced for studies of underlying biophysical mechanisms of intracellular transport and its potential applications in bioengeenering at micro- and nanoscale...
 
Yu-Hsiang Hsu, Monica L Moya, Christopher Hughes, Steven C George and Abraham Lee
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50424G, Paper
This paper reports a polydimethylsiloxane microfluidic model system that can develop an array of nearly identical human microtissues with interconnected vascular networks. The microfluidic system design is based on an...
 
Hao-Ting Huang, Tzong-Rong Ger, Ya-Hui Lin and Zung-Hang Wei
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50457C, Paper
Magnetic zigzag nanowire device was designed for single cell biosensor. Nanowires with widths 150, 300, 500, and 800 nm were fabricated on silicon trenches by electron beam lithography, electron beam...
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC41323C, Technical Innovation
DIB utility expanded using new fluidic devices that enable addition or perfusion of reagents.
 
Barry Lutz, Tinny Liang, Elain Fu, Sujatha Ramachandran, Peter Kauffman and Paul Yager
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50178G, Paper
Sugar solutions dried on paper create dissolvable flow delays that can be tuned from minutes to nearly an hour. We present a folding card format that uses paper networks and dissolvable delays to automate a multi-step signal-amplified immunoassay.
 
Chia-Yuan Chen, Chia-Yun Chen, Cheng-Yi Lin and Ya-Ting Hu
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50407G, Paper
We report an active micromixer using magnetically actuated artificial cilia to reach the optimum mixing performance for highly viscous flows.
 
Takuya Sunagawa, Akihito Tanahashi, Matthew E. Downs, Henry Hess and Takahiro Nitta
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC41103F, Paper
A design method inspired by biological evolution enabled automated designs of mechanical nanodevices powered by kinesin motors.
 
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50449B, Tutorial Review
Instrument miniaturization is one of the critical issues to improve sensitivity, speed, throughput, and to reduce the cost of analysis. Microfluidics possesses the ability to handle small sample amounts, with...
 
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50280E, Paper
We report a method for fabricating permeable polymer microstructure barriers in polydimethylsiloxane (PDMS) microfluidic devices and the use of the devices to capture and transport DNA and cells. The polymer...
 

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