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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in Medline
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Mun-Bum Song, Hyou-Arm Joung, Young Kyoung Oh, Young Deok Ahn, Kwonyoung Jung and Min-Gon Kim
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00521C, Paper
This article describes a new method, referred to as "tear-off patterning," for patterning nitrocellulose (NC) membranes in order to fabricate NC-based point-of-care (POC) diagnostic devices. Paper-based microfluidic sensors usually employ...
Nitesh Nama, Rune Barnkob, Zhangming Mao, Christian J. Kähler, Francesco Costanzo and Tony Jun Huang
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00231A, Paper
We present a numerical study of the acoustophoretic motion of particles suspended in a liquid-filled PDMS microchannel on a lithium niobate substrate acoustically driven by surface acoustic waves.
Ching-Hui Lin, Yi-Hsing Hsiao, Hao-Chen Chang, Chuan-Feng Yeh, Cheng-Kun He, Eric M. Salm, Chihchen Chen, Ing-Ming Chiu and Chia-Hsien Hsu
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00541H, Paper
In vitro culture of single cells facilitates biological studies by deconvoluting complications from cell population heterogeneity. However, there is still a lack of simple yet high-throughput method to perform single...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00503E, Paper
A user-friendly microfluidic chamber produces a passive, stable gradient of soluble cues for imaging and quantification of axon turning.
Ramya Veerubhotla, Aditya Bandopadhyay, Debabrata Das and Suman Chakraborty
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00211G, Communication
We present a low-cost, disposable microbial fuel cell fabricated on a paper based platform, having a start-up time of 10 s.
Majid Hejazian and Nam-Trung Nguyen
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00427F, Paper
We report magnetic manipulation of non-magnetic particles suspended in diluted ferrofluid. Diamagnetic particles were introduced into a circular chamber to study the extent of their deflection under the effect of...
Andy K. Tay, Manjima Dhar, Ivan Pushkarsky and Dino Di Carlo
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90060C, Highlight
Acoustic separation of circulating tumor cells – BLAST-ing large cargo into cells at high-throughput – Magnetic control of intracellular protein distribution.
Ilka Maschmeyer, Alexandra K. Lorenz, Katharina Schimek, Tobias Hasenberg, Anja P. Ramme, Juliane Hübner, Marcus Lindner, Christopher Drewell, Sophie Bauer, Alexander Thomas, Naomia Sisoli Sambo, Frank Sonntag, Roland Lauster and Uwe Marx
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00392J, Paper
We established a microfluidic four-organ-chip for interconnected long-term co-culture of human intestine (1), liver (2), skin (3) and kidney (4) equivalents.
K. Frykholm, L. K. Nyberg, E. Lagerstedt, C. Noble, J. Fritzsche, N. Karami, T. Ambjörnsson, L. Sandegren and F. Westerlund
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00378D, Communication
We demonstrate how circular bacterial plasmids can be automatically sized and discriminated from linear DNA fragments via stretching in nanochannels.
Shih-Mo Yang, Dapeng Zhang, Wang Chen and Shih-Chi Chen
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00448A, Paper
Arrays of NaCl crystal nucleation and crystal growth on a flow-free droplet-based device.
Jinzhen Fan, Baoqing Li, Siyuan Xing and Tingrui Pan
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00432B, Paper
A microfluidic dilution device for quantitative assays which simultaneously produces 1 to 100-fold dilution from 10 μL sample without pumps.
F. Haghighi, Z. Talebpour and A. Sanati-Nezhad
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00283D, Critical Review
In recent years, the need for measurement and detection of samples in situ or with very small volume and low concentration (low and sub-parts per billion) is a cause for miniaturizing systems via microelectromechanical system (MEMS) technology.
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00420A, Paper
Particle concentration is a basic operation needed to perform washing steps or to improve subsequent analysis in many (bio)-chemical assays. In this article we present field free, hydrodynamic accumulation of...
Jinzhou Yuan, Jessie Zhou, David Raizen and Haim H Bau
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00305A, Paper
Animal motility varies with genotype, disease, aging, and environmental conditions. In many studies, it is desirable to carry out high throughput motility-based sorting to isolate rare animals for, among other...
Sanjesh Yasotharan, Sascha Pinto, John G. Sled, Steffen-Sebastian Bolz and Axel Günther
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00021A, Paper
We present a compact microfluidic platform for the automated, multimodal assessment of intact small blood vessels in vitro.
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00326A, Paper
We present an on-chip liquid routing technique intended for application in well-based microfluidic systems that require long-term active pumping at low to medium flowrates. Our technique requires only one fluidic...
S. A. Byrnes, J. D. Bishop, L. Lafleur, J. R. Buser, B. Lutz and P. Yager
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00317B, Paper
Nucleic acid purification in porous membranes at the point-of-care from complex samples including nasal matrix and blood using a single-user step.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00245A, Paper
Inflammation on a chip.
Xiaojun Yan, Jingyu Wang, Lu Zhu, Jonathan Joseph Lowrey, Yuanyuan Zhang, Wei Hou, Jiahong Dong and Yanan Du
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00313J, Paper
A ready-to-use 3D scaffold-based immunoChip combined with a 3D cell culture chip for high throughput drug hepatotoxicity evaluation.
Minkyung Cho, Soyi Chung, Yong Tae Kim, Jae Hwan Jung, Do Hyun Kim and Tae Seok Seo
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00355E, Communication
An integrated microdevice, consisting of a micropump, a passive mixer, a magnetic separation chamber, and a microcapillary electrophoretic channel, was constructed for biobarcode assay based multiplex biological agent detection in...
Rerngchai Arayanarakool, Anne K Meyer, Linda Helbig, Samuel Sanchez and Oliver G. Schmidt
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00024F, Paper
Artificial microvasculature, particularly as part of the blood-brain barrier, has a high benefit for pharmacological drug discovery and uptake regulation. We demonstrate the fabrication of tubular structures with patterns of...
Ritika S. Petersen, Stephan S. Keller and Anja Boisen
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00372E, Communication
Hot punching: a highly versatile method of fabricating high-aspect-ratio 3D microstructures for drug delivery with good replication fidelity and yield.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00274E, Paper
Use feedback and wave methods (Fourier construction) to create sophisticated oil film geometries through incomplete electrical dewetting.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00140D, Paper
A microfluidic device that generates a stable, linear and diffusive chemical gradient over a biocompatible hydrogel with a stiffness gradient.
Jan Müller, Marco Ballini, Paolo Livi, Yihui Chen, Milos Radivojevic, Amir Shadmani, Vijay Viswam, Ian L. Jones, Michele Fiscella, Roland Diggelmann, Alexander Stettler, Urs Frey, Douglas J. Bakkum and Andreas Hierlemann
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00133A, Paper
Novel CMOS-based microelectrode array to enable high-spatiotemporal- resolution access to neuronal preparations on subcellular, cellular, and network level.

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