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Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 6.115 24 Issues per Year Indexed in Medline
 
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Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00396F, Paper
From themed collection Lab on a Chip Recent HOT Articles
A compact microfluidic device for normoxic perfusion culture of mammalian cells under in situ metabolomic observation by NMR spectroscopy is presented.
 
H. T. Zhao, Y. Yang, L. K. Chin, H. F. Chen, W. M. Zhu, J. B. Zhang, P. H. Yap, B. Liedberg, K. Wang, G. Wang, W. Ser and A. Q. Liu
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC90052F, Correction
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC90046A, Focus
Multiplexed point-of-care diagnostics (PoC) combined with smartphone technology are emerging sensor platforms that will be highly valuable for the improvement of world health in personalized medicine.
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00499G, Paper
Microfluidic paper-based analytical devices (μPADs) for molecular detection have great potential in the field of point-of-care diagnostics. Currently, a critical problem facing μPADs is improving their detection sensitivity. Various preconcentration...
 
Mei Kum Khaw, Chin Hong Ooi, Faisal Mohd-Yasin, Raja Vadivelu, James St John and Nam-Trung Nguyen
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00378H, Paper
Controlled actuation of a floating liquid marble, a liquid droplet coated with hydrophobic particles floating on another liquid surface, is a potential digital microfluidics platform for the transportation of aqueous...
 
Sidra Waheed, Joan M. Cabot, Niall P. Macdonald, Trevor Lewis, Rosanne M. Guijt, Brett Paull and Michael C. Breadmore
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00284F, Critical Review
From themed collection 3D Printing
3D printing has the potential to significantly change the field of microfluidics.
 
Olgierd Cybulski, Slawomir Jakiela and Piotr Garstecki
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00375C, Technical Innovation
We propose and test a new whole-Teflon gate valve for handling droplets. The valve allows to pass droplet plugs through without disturbing them. This is possible thanks to the geometric...
 
Hengdong Xi, Wei Guo, Michael Leniart, Zhuang Zhi Chong and Say Hwa Tan
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00448B, Communication
From themed collection 2016 Lab on a Chip Emerging Investigators
We present for the first time an experimental study on the droplet deformation induced by AC electric field in droplet-based microfluidics. It is found that the deformation of the droplets...
 
Zhixiong Zhang, Yu-Chih Chen, Yu-Heng Cheng, Yi Luan and Euisik Yoon
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00081A, Paper
The 3D cell culture in extracellular matrix (ECM), which not only provides structural support to cellular constituents, but also initiates regulatory biochemical cues for a variety of important cell functions...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00241B, Paper
Analysis of the intracellular materials of a small number of cancer cells at the single-cell level is important to improve our understanding of cellular heterogeneity in rare cells. To analyze...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00487C, Paper
From themed collection 2016 Lab on a Chip Emerging Investigators
Microfluidic devices can sort immunomagnetically labeled cells with sensitivity and specificity much greater than that of conventional methods, primarily because the size of microfluidic channels and micro-scale magnets can be...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00193A, Critical Review
From themed collection 3D Printing
Fabrication of vascular networks within engineered tissue remains one of the greatest challenges facing the fields of biomaterials and tissue engineering. Historically, the structural complexity of vascular networks has limited...
 
Min Cheol Park, Moojong Kim, Gun Taek Lim, Sung Min Kang, Seong An, Tae Song Kim and Ji Yoon Kang
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00013D, Paper
Multiwell plates are regulary used in analytical research and clinical diagnosis, however, often require laborious washing steps and large sample/reagent volume (typically, 100 μL well-1). In order to overcome such...
 
Z. Tatárová, J. P. Abbuehl, S. Maerkl and J. Huelsken
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00236F, Paper
A microfluidic chemotaxis assay which combines on-chip production of chemoattractants with multiplex analysis of migratory properties of primary stem cells.
 
Qiangqiang Fu, Ze Wu, Fangxiang Xu, Xiuqing Li, Cuize Yao, Meng Xu, Liangrong Sheng, Shiting Yu and Yong Tang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00083E, Paper
A smart phone-based PNRP operates by measuring the intensity of transmitted light using the ambient light sensor of a smart phone.
 
Pengfei Zhang, Jianxiong Zhang, Shengtai Bian, Zhongyao Chen, Yawei Hu, Ruowen Hu, Jiaqi Li, Yichun Cheng, Xiaochen Zhang, Yiming Zhou, Xiaofang Chen and Peng Liu
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00331A, Paper
From themed collection 2016 Lab on a Chip Emerging Investigators
A superhydrophobic microwell array chip (SMARchip) was developed for high-throughput screening.
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00265J, Technical Innovation
Many modern analytical assays, for example droplet digital PCR, or screening of the properties of single cells or single mutated genes, require splitting a liquid sample into a number of...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00307A, Paper
Electrochemical sensors are powerful analytical tools which possess the capacity for rapid detection of biomarkers in clinical specimens. While most electrochemical sensors are fabricated on rigid substrates, there is a...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00355A, Critical Review
Dielectrophoresis is a powerful technique used to distinguish distinct cellular identities in heterogeneous cell populations, monitor changes in the cell state without the need for biochemical tags including live and...
 
Gabriel Gruionu, Despina Bazou, Nir Maimon, Mara Onita-Lenco, Lucian G. Gruionu, Peigen Huang and Lance L. Munn
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00237D, Paper
From themed collection Lab on a Chip Recent HOT Articles
Implantable tissue isolation chambers allow analyses of host–tumor interactions in vivo.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00292G, Paper
From themed collection 3D Printing
Rapid prototyping of a meter-mix device to accurately meter, lyse, and transfer urine samples for LRS and POC diagnostics.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C5LC01556A, Critical Review
From themed collection Lab on a Chip: Recent Review Articles
The synergy of novel super-resolution imaging techniques and microfluidic technology provides new biological and biomedical insights into sub-cellular processes.
 
Andy Kah Ping Tay, Felix E. Schweizer and Dino Di Carlo
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00349D, Critical Review
Biomechanical forces have been demonstrated to influence a plethora of neuronal functions across scales including gene expression, mechano-sensitive ion channels, neurite outgrowth and folding of the cortices in the brain....
 
Jeonghun Nam, Yong Shin, Justin Kok Soon Tan, Bena Ying Lim, Chwee Teck Lim and Sangho Kim
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00162A, Paper
A novel microfluidic device for high-throughput particle separation using a viscoelastic fluid, which enables the rapid detection of extremely rare malaria parasites by using PCR analysis, is proposed. Our device...
 
Ayako Yamada, Maéva Vignes, Cécile Bureau, Alexandre Mamane, Bastien Venzac, Stephanie Descroix, Jean-Louis Viovy, Catherine Villard, Jean-Michel Peyrin and Laurent Malaquin
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00414H, Paper
Oriented neuronal networks with controlled connectivity are required for many applications ranging from studies of neurodegeneration to neuronal computation. To build such networks in vitro, an efficient, directed and long...
 

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