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Journal cover: Lab on a Chip

Lab on a Chip

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Kyuhawn Na, Mingyu Lee, Hyun-Woo Shin and Seok Chung
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01564F, Paper
The emergence of microfluidic epithelial models using diverse types of cells within a physiologically relevant microenvironment has the potential to be a powerful tool for preclinical drug screening and pathophysiologic...
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00221A, Paper
Label-free biodetection schemes compatible with standard CMOS fabrication methods constitute an important goal, as these are enabling tools for the mass production of high-sensitivity biosensors. Two-dimensional slab photonic crystal (2D...
Rahim Rahimi, Wuyang Yu, Manuel Ochoa and Babak Ziaie
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00074J, Paper
We demonstrate, for the first time, a facile and low-cost approach for integrating highly flexible and stretchable microfluidic channels into textile-based substrates. The integration of the microfluidics is accomplished by...
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00058H, Communication
Frequency tuning has emerged as an attractive alternative to conventional pumping techniques in microfluidics. Oscillating (AC) flow driven through a passive valve can be rectified to create steady (DC) flow,...
Iago Pereiro, Sanae Tabnaoui, Marc Fermigier, Olivia du Roure, Stephanie Descroix, Jean-Louis Viovy and Laurent Malaquin
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00063D, Paper
Fluidization, a process in which a granular solid phase behaves like a fluid under the influence of an imposed upward fluid flow, is routinely used in many chemical and biological...
James Che, Victor Yu, Edward B Garon, Jonathan Goldman and Dino Di Carlo
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00038C, Paper
Isolation and enumeration of circulating tumor cells (CTCs) from blood is important for determining patient prognosis and monitoring treatment. Methods based on affinity to cell surface markers have been applied...
Matthias Thiele, Andrea Knauer, Daniéll Malsch, Andrea Csáki, Thomas Henkel, J. Michael Köhler and Wolfgang Fritzsche
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00109F, Paper
We present a microfluidic setup for the reproducible synthesis of AuNPs with tunable shapes and sizes. It increases yield, lowers material consumption and time, and enables an efficient parameter screening.
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00016B, Critical Review
Microneedles is an efficient and minimally-invasive approach of transdermal drug delivery and extraction of skin interstitial fluid. Compared to solid microneedles made of silicon, metals and ceramics, polymeric microneedles have...
Amy T. Lam, Karina G. Samuel-Gama, Jonathan Griffin, Matthew Loeun, Lukas C. Gerber, Zahid Hossain, Nate J. Cira, Seung Ah Lee and Ingmar H. Riedel-Kruse
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00131B, Paper
We present a hardware setup and a set of executable commands for spatiotemporal programming and interactive control of a swarm of self-propelled microscopic agents (Euglena gracilis) inside a microfluidic chip.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00114B, Communication
Fabrication of an open-channel, paper-based microfluidic device, utilizing selective wettability, capable of generating water-in-oil emulsions and fabricating hydrogel particles.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00157F, Paper
This paper presents the formation of complex cross-sectional microfibers using three-dimensional microfluidic devices.
Collin B. Eaker, Ishan D. Joshipura, Logan R. Maxwell, Jason Heikenfeld and Michael D. Dickey
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC90029E, Correction
Haitao Yu, Shantanu Maheshwari, Jiu Yang Zhu, Detlef Lohse and Xuehua Zhang
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01555G, Paper
Surface nanodroplets are important units for lab-on-chip devices, compartmentalised catalytic reactions, high-resolution near-field imaging, and many others. Solvent exchange is a simple solution-based bottom-up approach for producing surface nanodroplets by...
Adam Mepham, Justin Besant, Adam Weinstein, Ian Burgess, Edward H Sargent and Shana O Kelley
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00199A, Paper
There is a growing need for power-free methods to manipulate small volumes of liquids and thereby enable use of diagnostic assays in resource-limited settings. Most existing self-powered devices provide analog...
Esther Amstad, Frans Spaepen, Michael P. Brenner and David A. Weitz
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01455K, Paper
Many powders employed in the food and pharmaceutical industries are produced through spray drying because it is a cost efficient process that offers control over the particle size.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00121E, Critical Review
Recent developments in the lab-on-PCB integration technology, highlighting its standardized industrial fabrication potential.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01343K, Paper
We present a dual-porosity micromodel with multiple etch depths for visualization of two-phase flow; flow is characterized via the micro particle image velocimetry technique. The images show different flow fields through tight portions of the pore space after dual-depth etching.
Rhonda Jack, Khadijah Hussain, Danika Rodrigues, Mina Zeinali, Ebrahim Azizi, Max Wicha, Diane M. Simeone and Sunitha Nagrath
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01496H, Paper
In light of the significance of tumor cell heterogeneity, we describe a facile workflow to isolate distinct groups of tumor cells immunomagnetically, according to their surface-protein expression levels.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00037E, Critical Review
Cellular heterogeneity has been widely recognized but only recently have single cell tools become available that allow characterizing heterogeneity at the genomic and proteomic levels.
L. D'Amico, N. J. Ajami, J. A. Adachi, P. R. C. Gascoyne and J. F. Petrosino
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01277A, Paper
This paper describes a method to isolate bacteria from blood using selective permeabilization of blood cells, membraneless dialysis, and dielectrophoresis.
Ruihua Tang, Hui Yang, Yan Gong, MinLi You, Zhi Liu, Jane Ru Choi, Ting Wen, Zhiguo Qu, Qibing Mei and Feng Xu
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01586G, Paper
A fully disposable and integrated paper-based device by integrating nucleic acid extraction, amplification and LFA could achieve nucleic acid testing.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00014F, Paper
A novel geometry of channels allows us to generate multiple monodisperse emulsions with a single syringe pump by means of step emulsification.
Ata Dolatmoradi, Elnaz Mirtaheri and Bilal El-Zahab
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00161D, Paper
Vesicles with various membrane stiffness values depending on their cholesterol content were separated using a thermo-acoustofluidic technique.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00078B, Paper
Liquid thermal gradient refractive index lens and using it to trapping single living cell in flowing environments.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01595F, Critical Review
We review recent advances achieved in the field of optical whispering gallery mode biosensors. We discuss major challenges that these label-free sensors are faced with on their way towards future real-world applications and introduce different approaches suggested to overcome these issues. We furthermore highlight their potential future applications.

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72 citations
In this paper, a review is carried out of how 3D printing helps to improve the fabrication of microfluidic devices, the 3D printing technologies currently used for fabrication and the future of 3D printing in the field of microfluidics.
DOI: 10.1039/C5LC00685F
Published: 22 Jul 2015
76 citations
We established a microfluidic four-organ-chip for interconnected long-term co-culture of human intestine (1), liver (2), skin (3) and kidney (4) equivalents.
DOI: 10.1039/C5LC00392J
Published: 13 May 2015
29 citations
3D printing has the potential to significantly change the field of microfluidics.
DOI: 10.1039/C6LC00284F
Published: 25 Apr 2016

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