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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.586 24 Issues per Year Indexed in Medline
 
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Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC90088G, Focus
In this Focus article we will discuss some of the recent advances in bio-inspired materials and bio-hybrid systems for soft robotics applications in biomedicine.
 
Lisa K. Lafleur, Joshua D. Bishop, Erin K. Heiniger, Ryan P. Gallagher, Maxwell D. Wheeler, Peter Kauffman, Xiaohong Zhang, Enos C. Kline, Joshua R. Buser, Sujatha Kumar, Samantha A. Byrnes, Nicolaas M. J. Vermeulen, Noah K. Scarr, Yevgeniy Belousov, Walt Mahoney, Bhushan J. Toley, Paula D. Ladd, Barry R. Lutz and Paul Yager
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00677A, Paper
This diagnostic system prototype is the first demonstration of a fully integrated, simple-to-use nucleic acid amplification test device.
 
Seung-min Park, Jae Young Lee, Soongweon Hong, Sang Hun Lee, Ivan K. Dimov, Hojae Lee, Susie Suh, Qiong Pan, Keyu Li, Anna M. Wu, Shannon M. Mumenthaler, Parag Mallick and Luke P. Lee
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00762G, Communication
Microwell-based cytometry for simultaneous gene and protein measurements from single cells.
 
Armend G. Håti, David C. Bassett, Jonas M. Ribe, Pawel Sikorski, David A. Weitz and Bjørn T. Stokke
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00769D, Paper
Alginate is used extensively in microfluidic devices to produce discrete beads or fibres at the microscale. Here we showcase a new method to gel alginate on chip that has several advantages over existing approaches.
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00748A, Paper
The ability to accurately measure flow rate, concentration, and temperature in real-time in micro total analysis systems (µTAS) is crucial when improving their practical sensing capabilities within extremely small volumes....
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00707D, Critical Review
This article reviews lab on a chip devices based on arrays of microfabricated magnetic features and presents the microscale operations enabled by this technology, e.g., transport, separation and detection of magnetic beads and magnetically labelled biological analytes.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00867D, Paper
This paper presents a powerful tool to fabricate disposable and inexpensive PDMS nanofluidic chips with single nanochannels or nanochannel arrays.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00829A, Tutorial Review
This review discusses epigenetics and the microfluidic platforms developed for DNA methylation analysis.
 
Tae-Hyeong Kim, Vijaya Sunkara, Juhee Park, Chi-Ju Kim, Hyun-Kyung Woo and Yoon-Kyoung Cho
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00629A, Paper
This paper reports a robust, reversible and thermally stable valving technique on a lab-on-a-disc.
 
Alexandre Poulin, Cansaran Saygili Demir, Samuel Rosset, Tatjana Petrova and Herbert R Shea
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00903D, Paper
We demonstrate the use of dielectric elastomer actuators (DEAs) for mechanical stimulation of cells in vitro. The development of living tissues is regulated by their mechanical environment through the modification...
 
Dan Yuan, Jun Zhang, Ronald Sluyter, Qianbin Zhao, Sheng Yan, Gursel Alici and Weihua Li
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00843G, Paper
In this paper, continuous plasma extraction under viscoelastic fluid in a straight channel with asymmetrical expansion–contraction cavity arrays (ECCA channel) is demonstrated by exploiting the dean-flow-coupled elasto-inertial effects. First, the...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00718J, Critical Review
More than 90% of cancer-related deaths can be attributed to the occurrence of metastatic disease. Recent studies have highlighted the importance of the multicellular, biochemical and biophysical stimuli from the...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00844E, Paper
Nanofluidic energy harvesting systems have attracted interest in the field of battery application, particularly for miniaturized electrical devices, because they possess excellent energy conversion capability for their size. In this...
 
Zhaoxiong Ding, Dongying Zhang, Guanghui Wang, Minghui Tang, Yumin Dong, Yixin Zhang, Ho-pui Ho and Xuping Zhang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00542J, Paper
We demonstrated an inline spectrophotometer on centrifugal microfluidics based on the PEDD method, and used it for real-time protein determination and calibration on a chip.
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00742B, Paper
We report an in situ biofabrication strategy that conveniently partitions microfluidic networks into physically separated while chemically communicating microchannels with semipermeable biopolymer membranes, which enale the facile generation of static...
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00949B, Paper
We developed a sensitive thermometer using a vacuum-packed Si resonator in a microfluidic chip for a single brown fat cell.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00827E, Paper
We show a simpler and more cost-effective method for generating surface acoustic waves using eutectic gallium indium as a conductive liquid which can replace conventional patterned metal electrodes.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00633G, Technical Innovation
Electrokinetic stacking based on field amplification was firstly introduced to a paper-based analytical device, and over 1000-fold signal improvement was achieved.
 
David J. Kinahan, Philip L. Early, Abhishek Vembadi, Eoghan MacNamara, Niamh A. Kilcawley, Thomas Glennon, Dermot Diamond, Dermot Brabazon and Jens Ducrée
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00568C, Technical Innovation
Valves on a Lab-on-a-Disc are actuated, with disc in motion and with arbitrary timing, by a knife-cutter based robotic arm.
 
Ravi Kumar Arun, Preeti Singh, Gautam Biswas, Nripen Chanda and Suman Chakraborty
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00820H, Paper
We report an ultra-low-cost device for energy conversion by exploiting the capillary flow of an electrolyte on a filter paper matrix in which a naturally deposited gradient of reduced graphene oxide is induced through chemical synthesis.
 
Patrícia Moura Rosa, Nimi Gopalakrishnan, Hany Ibrahim, Markus Haug and Øyvind Halaas
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00702C, Paper
T cells play a central role in immunity towards cancer and infectious diseases. T cell responses are initiated in the T cell zone of the lymph node (LN), where resident...
 
Ayokunle Oluwafemi Olanrewaju, Alessandra Robillard, Milad Dagher and David Juncker
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00764C, Paper
We recently developed capillaric circuits (CCs) – advanced capillary microfluidic devices assembled from capillary fluidic elements in a modular manner similar to the design of electric circuits (Safavieh & Juncker,...
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00778C, Paper
A high-throughput single cell analysis microfluidic chip was developed for single-cell derived sphere assays with automatic cell and sphere image analysis.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00661B, Paper
We propose a robust method for fabricating concave microwells utilizing metal beads, a through-hole array, and an assembly of small magnets. The spherical metal beads were used as a mold for the microwell, naturally creating the desired 3D concave microwell geometry.
 
Mary-Anne Nguyen, Bernadeta Srijanto, C. Patrick Collier, Scott T. Retterer and Stephen A. Sarles
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00810K, Paper
This work demonstrates a low-volume microfluidic system that enables rapid assembly of droplet interface bilayers with in situ electrical characterization.
 

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37 citations
In this paper, a review is carried out of how 3D printing helps to improve the fabrication of microfluidic devices, the 3D printing technologies currently used for fabrication and the future of 3D printing in the field of microfluidics.
DOI: 10.1039/C5LC00685F
Published: 22 Jul 2015
48 citations
This review surveys the leading approaches for sorting cells in microfluidic devices and organizes those technologies by the many physical mechanisms exploited for sorting.
DOI: 10.1039/C4LC01246A
Published: 06 Jan 2015
35 citations
We established a microfluidic four-organ-chip for interconnected long-term co-culture of human intestine (1), liver (2), skin (3) and kidney (4) equivalents.
DOI: 10.1039/C5LC00392J
Published: 13 May 2015

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