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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
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Ayako Yamada, Renaud Renault, Aleksandra Chikina, Bastien Venzac, Iago Pereiro, Sylvie Coscoy, Marine Verhulsel, Maria Carla Parrini, Catherine Villard, Jean-Louis Viovy and Stephanie Descroix
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01143H, Paper
We report here a simple yet robust transient compartmentalization system for microfluidic platforms. Cylindrical microfilaments made of commercially available fishing lines are embedded in a microfluidic chamber and employed as...
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01098A, Paper
An artificial control of bio-nano machines should have a major impact on the development of controllable transport systems for specific cargo transport on chips. Precise spatiotemporal control and local regulation...
Brandon L. Thompson, Christopher Birch, Daniel A. Nelson, Jingyi Li, Jacquelyn A. DuVall, Delphine Le Roux, An-Chi Tsuei, Daniel L. Mills, Brian E. Root and James P. Landers
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00953K, Paper
A centrifugal microdevice with integrated gold leaf electrodes capable of high resolution electrophoretic separation of DNA fragments.
Margherita Bassu, Peter Holik, Sam Schmitz, Siegfried Steltenkamp and Thomas P. Burg
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01089J, Paper
We describe the fabrication of ultra uniform nanoslit arrays and their application to continuous separation of small molecules by charge.
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00981F, Paper
At the sub-millimeter scale, capillary forces enable robust and reversible adhesion between biological materials and varied substrates.
M. Li, H. E. Muñoz, A. Schmidt, B. Guo, C. Lei, K. Goda and D. Di Carlo
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01118G, Paper
We study the behaviors of ellipsoidal microalgal cells with varying aspect ratios using inertial microfluidics for biofuels and environmental applications.
Weiqian Jiang, Mingqiang Li, Zaozao Chen and Kam Leong
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01193D, Critical Review
Regenerating the diseased tissue is one of the foremost concerns for the millions of patients who suffer from tissue damage each year. Local delivery of cell-laden hydrogels offers an attractive...
C. S. Ball, R. F. Renzi, A. Priye and R. J. Meagher
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01104G, Paper
Laser cut microfluidic check valves enable staged reagent delivery, pumping, and point of care nucleic acid amplification testing.
Dogyeong Ha, Jisoo Hong, Heungjoo Shin and Taesung Kim
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01058J, Critical Review
Novel, unconventional micro-/nanofabrication technologies make it possible to fabricate various hybrid-scale lab-on-a-chip devices in an efficient, convenient, and high-throughput manner.
D. Caballero, J. Katuri, J. Samitier and S. Sánchez
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC90107G, Focus
In this Focus article we discuss recent advances in the use of ratchet-like geometries in microfluidics which could open new avenues in biomedicine for applications in diagnosis, cancer biology, and bioengineering.
Ian Swyer, Ronald Soong, Michael D. M. Dryden, Michael Fey, Werner E. Maas, André Simpson and Aaron R. Wheeler
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01073C, Paper
We introduce a digital microfluidic method for interfacing with nuclear magnetic resonance spectroscopy (DMF–NMR) for microscale chemical analysis.
Chi Long Chan, Guido Bolognesi, Archis Bhandarkar Bhandarkar, Mark Friddin, Nicholas Jan Brooks, John Seddon, Robert V. Law, Laura MC Barter and Oscar Ces
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01219A, Paper
In this study, we introduce an optofluidic method for the rapid construction of large-area cell-sized droplet assemblies with user-defined two-dimensional patterns of functional droplets. Light responsive water-in-oil droplets capable of...
Bugra Ayan, Adem Ozcelik, Hunter Bachman, Shi-Yang Tang, Yuliang Xie, Mengxi Wu, Peng Li and Tony Jun Huang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00951D, Paper
Herein, we have demonstrated coating of particles and cells utilizing the taSSAW approach.
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00967K, Paper
A novel, facile, and flexible approach for the easy assembly of microfluidic droplet devices using commercially available components is presented. Three different types of devices have been designed and tested,...
R. Peng, Z. Sonner, A. Hauke, E. Wilder, J. Kasting, T. Gaillard, D. Swaille, F. Sherman, X. Mao, J. Hagen, R. Murdock and J. Heikenfeld
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01013J, Paper
Reported here is a new paradigm in sweat sampling and sensing, where sample volumes are dramatically reduced and where analyte contamination from the skin surface is mitigated.
Yonglei Li, Yangfu Fang, Jiao Wang, Lu Wang, Shiwei Tang, Chunping Jiang, Lirong Zheng and Yongfeng Mei
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01148A, Paper
Tubular microcavities fully integrated with liquid reservoirs and coupled waveguides are fabricated utilizing the two-photon polymerization method as on-chip sensitive optofluidic refractometers.
Chen Wang, Feiyan Cai, Fei Li, Long Meng, Jiangyu Li, Junru Wu, Yan Kang and Hairong Zheng
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01151A, Paper
Liquid sensing is achieved by using a slotted phononic crystals plates (SPCP). The sensing mechanism is based on the fact that an acoustic wave confined in a small liquid slot...
Yan Ma, Jian-Zhang Pan, Shi-Ping Zhao, Qi Lou, Yng Zhu and Qun Fang
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00823B, Technical Innovation
Establishing cell migration assay in multiple different microenvironments is important in the study of tissue repair and regeneration, cancer progression, atherosclerosis, and arthritis. In this work, we developed a miniaturized...
Yinuo Cheng, Yue Wang, Zengshuai Ma, Wenhui Wang and Xiong-Ying Ye
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01113F, Technical Innovation
Microfiltration is a compelling method to separate particles based on their distinct size and deformability. However, this approach is prone to clogging after processing a certain number of particles and...
Lu Mi, Liang Huang, Junxiang Li, Guoqiang Xu, Qiong Wu and Wenhui Wang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01120A, Communication
Equivalent resistive electric circuit inspired, deterministic single cell trap with high efficiency and flexibility for large scale cell patterning.
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01121G, Paper
From themed collection 2016 Lab on a Chip Emerging Investigators
A wash-free droplet microfluidic platform for C-reactive-protein-based diagnosis with reduced assay time and enhanced sensitivity.
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01157H, Paper
The plastic tube with on-tube single-NW sensors demonstrates the advantages of low cost, fast response, and an easy-to-use breath-sensing procedure.
Yang Shi, Xiaoqiang Zhu, Li Liang and Yi Yang
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01115B, Paper
Fresnel zone plate (FZP) is a unique diffractive optical device and widely used in optical system such as interferometer and antenna. Traditional FZP utilizes solid materials and cannot be modulated...
Tzu-Heng Wu, Chia-Chen Chang, Julien Valliant, Aurélien BRUYANT and Chii-Wann Lin
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC01170E, Technical Innovation
Smartphone camera based gold nano-particle colorimetry (SCB-AuNP colorimetry) have shown good potentials for point-of-care applications. However, due to the use of camera as photo-detector, there are major limitations to this...
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC01005A, Paper
We present a microfluidic approach for studying signaling via secreted compounds between two specific C. elegans populations over prolonged durations.

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45 citations
In this paper, a review is carried out of how 3D printing helps to improve the fabrication of microfluidic devices, the 3D printing technologies currently used for fabrication and the future of 3D printing in the field of microfluidics.
DOI: 10.1039/C5LC00685F
Published: 22 Jul 2015
61 citations
This review surveys the leading approaches for sorting cells in microfluidic devices and organizes those technologies by the many physical mechanisms exploited for sorting.
DOI: 10.1039/C4LC01246A
Published: 06 Jan 2015
48 citations
We established a microfluidic four-organ-chip for interconnected long-term co-culture of human intestine (1), liver (2), skin (3) and kidney (4) equivalents.
DOI: 10.1039/C5LC00392J
Published: 13 May 2015

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