Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
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Camille Duprat, Helene Berthet, Jason S. Wexler, Olivia du Roure and Anke Lindner
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01034E, Paper
Gels are a functional template for micro-particle fabrication and microbiology experiments. The control and knowledge of their mechanical properties is critical in a number of applications, but no simple in...
P. Karásek, Jakub Grym, M. Roth, Josef Planeta and Frantisek Foret
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00843J, Paper
A novel method of etching channels in glass microchips with the most tunable solvent, water, was tested as an alternative to common hydrogen fluoride-containing etchants. The etching properties of water...
Jan Behrens, Sean Langelier, Amgad R. Rezk, Gerhard Lindner, Leslie Y. Yeo and James R. Friend
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00704B, Communication
A versatile, low-power traveling wave SAW microfluidic sorting device using a Schröder diffuser, adopted from its typical use in concert halls to the microscale.
Sha He, Yi Zhang, Pei Wang, Xingzhi Xu, Kui Zhu, Wenying Pan, Wenwen Liu, Kaiyong Cai, Jiashu Sun, Wei Zhang and Xingyu Jiang
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00901K, Paper
A high-throughput, high-efficiency and straightforward microfluidic blotting method for analyzing proteins and nucleic acids.
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01143K, Paper
An electrokinetic trapping (EKT)-based nanofluidic preconcentration device with the capability of label-free monitoring of trapped biomolecules through real-time dual-loop electric current measurement was demonstrated. Universal current-voltage (I-V) curves of EKT-based...
Théo Cambier, Thibault Honegger, Valérie Vanneaux, Jean Berthier, David Peyrade, Laurent Blanchoin, Jerome Larghero and Manuel Théry
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00807C, Paper
We designed a very simple 2D array of chambers protected from flow and supplied by a single inlet in order to easily monitor and stain hematopoietic stem cells over long periods of time.
Gisele Elias Nunes-Pauli, Alfredo de la Escosura-Muñiz, Claudio Parolo, Ivan H Bechtold and Arben Merkoçi
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01123F, Paper
We have developed a paper and gold nanoparticle (AuNP)-based lab-in-a-syringe (LIS) for immunosensing of biomarkers. This simple diagnostic device features simultaneous sampling and vertical-flow operation, meaning that unlike typical immunosensors,...
Mayuree Chanasakulniyom, Andrew Glidle and Jonathan M. Cooper
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00774C, Paper
Cell proliferation and migration are fundamental processes in determining cell and tissue behaviour.
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01069H, Paper
Self-sustainable energy sources are essential for a wide array of wireless applications deployed in remote field locations. Due to their self-assembling and self-repairing properties, “biological solar (bio-solar) cells” are recently...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00987H, Paper
Numbering-up of microchannels was experimentally investigated in a multichannel liquid–liquid micromixer using a model reaction through the blocking strategy.
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01194E, Communication
Fluorescence-activated droplet sorting is an important tool for droplet microfluidic workflows, but published approaches are unable to surpass throughputs of a few kilohertz. We present a new geometry that replaces...
Huanhuan Feng, Dmitry Ershov, Thomas Krebs, Karin Schroen, Martien A. Cohen Stuart, Jasper van der Gucht and Joris Sprakel
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00773E, Paper
Combining microcentrifugation, synchronized high-speed imaging and image processing allows direct measurement of coalescence dynamics in thermoresponsive emulsions.
Raffaella Molteni, Elena Bianchi, Paolo Patete, Monica Fabbri, Guido Baroni, Gabriele Dubini and Ruggero Pardi
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC00741G, Paper
Our device enables qualitative and quantitative assessment in 4D of the interdependent steps underlying circulating cell recruitment to tissues.
Christopher L. Cassano, Andrew J. Simon, Wei Liu, Carl Fredrickson and Z. Hugh Fan
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00927D, Technical Innovation
Vacuum bagging technique has been adapted for fabricating thermoplastic microfluidics devices, yielding strong bonding with little channel deformation.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC01031K, Paper
In this paper, an efficient microplatform based on reverse electrodialysis, which enables high ionic flux through three dimensional nanochannel networks for high power energy generation, is demonstrated.
Marie-Eve Myrand-Lapierre, Xiaoyan Deng, Richard R. Ang, Kerryn Matthews, Aline T. Santoso and Hongshen Ma
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC01100G, Paper
Mechanism for multiplexed measurement of single red blood cell deformability to evaluate pathological cells in a heterogeneous sample.
Mais J. Jebrail, Ronald F. Renzi, Anupama Sinha, Jim Van De Vreugde, Carmen Gondhalekar, Cesar Ambriz, Robert J. Meagher and Steven S. Branda
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00703D, Paper
Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications.
Gui-Ping Zhu, Majid Hejiazan, Xiaoyang Huang and Nam-Trung Nguyen
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00885E, Paper
We investigated the phenomenon of magnetophoresis of diamagnetic microparticles suspended in a ferrofluid in a weak uniform magnetic field. No high field gradient is required for particle migration.
Hongyan Song, Ten It Wong, Anton V. Sadovoy, Lin Wu, Ping Bai, Jie Deng, Shifeng Guo, Yi Wang, Wolfgang Knoll and Xiaodong ZHOU
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00978A, Paper
We designed and fabricated two new nanostructured biosensing chips, with which the sensitive detection of prostate specific antigen (PSA) as low as 100 pg/ml can be achieved, by measuring the...
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01218F, Paper
Micropipette aspiration measures the mechanical properties of single cells. A traditional micropipette aspiration system requires a bulky infrastructure, and has a low throughput and limited potential for automation. We have...
Andrea Lamberti, Angelo Angelini, Serena Ricciardi and Francesca Frascella
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01027B, Technical Innovation
Herein we have proposed for the first time the exploitation of holed-designed PDMS membrane as innovative passive microarray spotter. The elastomeric membrane was fabricated taking advantage of very simple technological...
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00472H, Technical Innovation
An LED-based UV-light source producing collimated uniform illumination over a large area is built and used to fabricate PDMS microchannels with near-rectangular profiles and depths up to 300 μm.
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01009D, Paper
A microfluidic device for studies on the germination of bacterial spores (e.g. Bacillus subtilis) based on non-specific interactions in nanoscale is presented. A decrease in the population of spores during...
zhixiong Hu, Andrew Glidle, Charles Ironside, Jonathan M Cooper and Huabing Yin
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00952E, Paper
We describe the development of an integrated, lensed Arrayed Waveguide Grating (AWG) microspectrometer for localized multiplexing fluorescence measurements. The device, which has a footprint of only 1mm wide and 1cm...
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00877D, Paper
We demonstrate that a fluorinated elastomer, called perfluoropolyether (PFPE), can be an alternative oxygen permeable elastomer for stop flow lithography (SFL) microfluidic channels. The PFPE channels can allow for the solvent-based synthesis of complex anisotropic particles, greatly enhancing the synthesis capabilities of SFL.

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