Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
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Miao Yu, Youmin Hou, Hongbo Zhou and Shuhuai Yao
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01480D, Paper
We developed an on-demand nanofluidic concentrator that can adaptively encapsulate highly concentrated samples and enhance long-term stability for further analysis.
Radin Tahvildari, Eric Beamish, Vincent Tabard-Cossa and Michel Godin
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01366B, Technical Innovation
Functional low-noise nanopore arrays are fabricated by controlled dielectric breakdown in solid-state membranes integrated within microfluidic devices.
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01135J, Paper
In this work, we first report a facile, low-cost and high-throughput method for photolithographical fabrication of microfluidic cloth-based analytical devices (μCADs) by simply using the cotton cloth as substrate material...
Coleman Murray, Oladunni Adeyiga, Keegan Owsley and Dino Di Carlo
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90017D, Highlight
Single-cell morphological analysis – gradient antibiotic susceptibility – rapid bacterial detection in blood.
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01369G, Paper
Microsystems designed for cell-based studies or applications inherently require fluid handling. Flows within such systems inevitably generate fluid shear stress (FSS) that may adversely affect cell health. Simple assays of...
Amir M. Foudeh, Daniel Brassard, Maryam Tabrizian and Teodor Veres
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01468E, Paper
Despite recent advances in the miniaturization and automation of biosensors, technologies for on-site monitoring of environmental water are still at an early stage of development. Prevention of outbreaks caused by...
T. Yang, P. Paiè, G. Nava, F. Bragheri, R. Martinez Vazquez, P. Minzioni, M. Veglione, M. Di Tano, C. Mondello, R. Osellame and I. Cristiani
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01496K, Communication
Cell sorting based on mechanical properties is demonstrated using an optofluidic chip by extracting highly metastatic cells from a heterogeneous population.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01384K, Paper
We present a microfluidic device for high-resolution imaging and sorting of early larval C. elegans. The animals are isolated in droplets and temporarily immobilized for imaging using a reversible hydrogel.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01439A, Paper
Optimal design and fabrication of novel devices for high-performance optofluidic applications is a key issue for the development of advanced lab-on-a-chip systems.
Micheal Leser, Jonathan Pegan, Mohammed El Makkaoui, Joerg C. Schlatterer, Michelle Khine, Matt Law and Michael Brenowitz
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01288G, Technical Innovation
The structure of macromolecules and their complexes dictate their biological function. In “footprinting”, the solvent accessibility of the residues that constitute proteins, DNA and RNA can be determined from their...
Frank Schwemmer, Steffen Zehnle, Daniel Mark, Felix von Stetten, Roland Zengerle and Nils Paust
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01269K, Paper
Accurate timing of microfluidic operations is essential for the automation of complex laboratory workflows, in particular for the supply of sample and reagents. Here we present a new unit operation...
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01266F, Paper
This paper describes an underwater micro propulsion principle where a gaseous bubble trapped in a suspended microchannel and oscillated by an external acoustic excitation generates a propelling force. The propelling...
R. E. Gerver, R. Gómez-Sjöberg, B. C. Baxter, K. S. Thorn, P. M. Fordyce, C. A. Diaz-Botia, B. A. Helms and J. L. DeRisi
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90018B, Correction
Hyunjoo Jenny Lee, Yoojin Son, Jeongyeon Kim, Changjoon Justin Lee, Eui-Sung Yoon and Il-Joo Cho
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01321B, Paper
Multi-functional neural probes integrated with various stimulation modalities are becoming essential tools in neuroscience to study brain more effectively. In this paper, we present a new multi-functional neural probe that...
Kyoung G. Lee, Sujeong Shin, Byeong Il Kim, Nam Ho Bae, Moon-Keun Lee, Seok-Jae Lee and Tae Jae Lee
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01473A, Technical Innovation
Perfect sealing of heterogeneous microstructures in plastic-based microfluidic devices is significant and urgent challenges to apply them in various microfluidic-based applications including biosensing, biofiltering, chemical reactors and lab-on-a-chip. In this...
Robert Lin, Arunan Skandarajah, Rachel E. Gerver, Hector D. Neira, Daniel A. Fletcher and Amy E. Herr
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01370K, Paper
Antibodies against the hepatitis C virus are detected in human sera using the CellScope-enabled electrophoretic barcode assay.
N. Gopalakrishnan, R. Hannam, G. P. Casoni, D. Barriet, J. M. Ribe, M. Haug and Ø. Halaas
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01438C, Paper
Immunity on a chip: modeling and designing immune reactions in vitro to study immune responses on a chip as well as unraveling physiological processes under a microscope.
Hsieh-Fu Tsai, Yi-Ching Tsai, Sharon Yagur-Kroll, Noa Palevsky, Shimshon Belkin and Ji-Yen Cheng
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01189A, Paper
This is a portable system for water contamination monitoring. Using live bacterial cells as bioreporters, we integrate temperature control, microfluidic sample introduction, bioluminescence detection, and recording software into a complete system.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01127A, Paper
A stacking flow platform for single-step detection of a target antibody in salivary fluid with improved flow uniformity and reduced background.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01070A, Paper
Microfluidic platform for generating dynamic profile of cell stimuli for non-adherent cells.
S. Durán, S. Novo, M. Duch, R. Gómez-Martínez, M. Fernández-Regúlez, A. San Paulo, C. Nogués, J. Esteve, E. Ibañez and J. A. Plaza
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01299B, Paper
We develop chip-on-a-cell barcodes featuring silicon nanowires as nanoscale attachment to label living mouse embryos.
Bhushan J. Toley, Jessica A. Wang, Mayuri Gupta, Joshua R. Buser, Lisa K. Lafleur, Barry R. Lutz, Elain Fu and Paul Yager
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01155D, Paper
A versatile, powerless, valving and automation toolkit for paper microfluidic devices that uses absorbent expanding elements as actuators is presented.
Susan H. Roelofs, Bumjoo Kim, Jan C. T. Eijkel, Jongyoon Han, Albert van den Berg and Mathieu Odijk
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01410C, Paper
We demonstrate capacitive deionization in a microfluidic chip and monitor the salt concentration between the desalination electrodes in real-time.
S. Xiong, L. K. Chin, K. Ando, T. Tandiono, A. Q. Liu and C. D. Ohl
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01184H, Paper
The transformation process of a bubble to a droplet is experimentally demonstrated by focusing a pulse laser near a gas–liquid interface in a nanofluidic channel.
Seungjeong Song, Minseok S. Kim, Jaeyeon Lee and Sungyoung Choi
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01417K, Communication
This communication presents a microfluidic method for size-based cell sorting, which provides a simple and robust approach for cell cycle synchronization by manual and stand-alone operation.

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