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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in Medline
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Jiajie Chen, Zhiwen Kang, Guanghui Wang, Fong-Chuen Loo, Siu-Kai Kong and Ho-Pui Ho
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00406C, Paper
We present a versatile optofluidic flow manipulation scheme based on plasmonic heating in random gold nanoisland substrate (Au-NIS). With its highly efficient conversion of optical power to hydrodynamic actuation, the...
Friedrich Schuler, Frank Schwemmer, Martin Trotter, Simon Wadle, Roland Zengerle, Felix von Stetten and Nils Paust
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00291E, Paper
Aqueous microdroplets provide miniaturized reaction compartments for numerous chemical, biochemical or pharmaceutical applications. We introduce centrifugal step emulsification for the fast and easy production of monodispers droplets. Homogenous droplets with...
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00379B, Paper
We present a novel microfluidic EDGE (Edge based Droplet GEneration) device with regularly spaced micron-sized partitions, which is aimed at upscaling of o/w emulsion preparation. By this means, remarkably higher...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00217F, Paper
Simple microfluidic flow focusing generation of droplets from ultralow interfacial tension aqueous two phase systems (ATPS).
Yingnan Sun, Xiaodong Chen, Xiaoguang Zhou, Jinbiao Zhu and Yude Yu
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00356C, Paper
We introduce a new model to describe the multiple printing procedure implemented by the inkjet printing approach. This non-contact and sequential picoliter droplet printing technology is named as sequential inkjet printing.
David J. Guckenberger, Theodorus E. de Groot, Alwin M. D. Wan, David J. Beebe and Edmond W. K. Young
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00234F, Tutorial Review
Micromilling is a fast and simple method capable of fabricating complex 2D or 3D microdevices compatible with cell culture and microscopy.
Hengky Chandrahalim, Qiushu Chen, Ali A. Said, Mark Dugan and Xudong Fan
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00254K, Paper
Optofluidic ring resonator laser fabricated using 3-D femto-second laser writing technology.
Jemish Parmar, Seungwook Jang, Lluís Soler, Dong-Pyo Kim and Samuel Sánchez
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90047F, Focus
This article focuses on recent developments in novel nano-photocatalyst materials to enhance photocatalytic activity. Recent reports on optofluidic systems, new synthesis of photocatalytic composite materials and motile photocatalysts are discussed.
Shaohua Ma, Joseph M. Sherwood, Wilhelm T. S. Huck and Stavroula Balabani
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00346F, Paper
The flow environment in inner cores of water-in-oil-in-water (w/o/w) microfluidic double emulsions has a significant impact on industrial applications of such systems.
K. C. Hribar, D. Finlay, X. Ma, X. Qu, M. G. Ondeck, P. H. Chung, F. Zanella, A. J. Engler, F. Sheikh, K. Vuori and S. C. Chen
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00159E, Paper
Nonlinear 3D projection printing is developed to generate concave hydrogel microstructures for 3D cell spheroid and embryoid body formation and long-term culture.
Edinson Lucumi Moreno, Siham Hachi, Kathrin Hemmer, Sebastiaan J. Trietsch, Aidos S. Baumuratov, Thomas Hankemeier, Paul Vulto, Jens C. Schwamborn and Ronan M. T. Fleming
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00180C, Paper
Differentiation of hNESC into functional dopaminergic neurons in phase-guided 3D microfluidic cell culture.
Mikael Evander, Olof Gidlöf, Björn Olde, David Erlinge and Thomas Laurell
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00290G, Paper
Microparticles (MP) are small (100-1000 nm) membrane vesicles shed by cells as a response to activation, stress or apoptosis. Platelet-derived MP (PMP) has been shown to reflect the pathophysiological processes...
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00139K, Paper
A handheld flow genetic analysis system (FGAS) is proposed for rapid, sensitive, multiplex, real-time quantification of nucleic acids at the point-of-care (POC) level. The FGAS includes a helical thermal-gradient microreactor...
Matthew Myles Shindel and Eric M Furst
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00351B, Paper
Coupling analog frequency modulation (FM) to the driving stimulus in active microrheology measurements conducted with optical tweezers effectively parallelizes numerous single-frequency experiments. Consequently, frequency modulated microrheology (FMMR) can efficiently characterize...
Robert Raimund Niedl and Carsten Beta
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00276A, Paper
Paper-based microfluidics provide an inexpensive, easy to use technology for point-of-care diagnostics in developing countries. Here, we combine paper-based microfluidic devices with responsive hydrogels to add an entire new class...
Cong Xue, Chen Yang, Tiegang Xu, Jing Zhan and Xinxin Li
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00361J, Paper
A magneto-elastic resonant ‘micro-diver’ system (MER-μDS) is proposed and developed for rapid liquid-phase detection of pathogens in a wireless way.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00182J, Paper
We present an automated microfluidic co-culture system that allows us to study spatiotemporal signal propagation from a single activated cell to a population of cells.
Mohamed Lemine Youba Diakite, Jérôme Rollin, Dorothée Jary, Jean Berthier, Chantal Mourton-Gilles, Didier Sauvaire, Cathy Philippe, Guillaume Delapierre and Xavier Gidrol
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00178A, Paper
We established a gene expression profile resulting from ricin exposure and demonstrated its ability to classify exposed vs. non-exposed mice with a drop of blood using an integrated microfluidic cartridge.
Han Wei Hou, Roby P. Bhattacharyya, Deborah T. Hung and Jongyoon Han
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00311C, Paper
Isolation of low-abundance bacteria from whole blood for direct pathogen identification and antibiotic susceptibility determination using hybridization-based RNA detection.
M. A. Modestino, M. Dumortier, S. M. Hosseini Hashemi, S. Haussener, C. Moser and D. Psaltis
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00259A, Paper
Water-splitting devices that operate with humid air feeds are an attractive alternative for hydrogen production as the required water input can be obtained directly from ambient air.
Antonella Zacheo, alessandra zizzari, elisabetta perrone, Luigi Carbone, Gabriele Giancane, Ludovico Valli, Ross Rinaldi and Valentina Arima
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01419G, Technical Innovation
Glass micromachining is a basic technology to achieve microfluidic networks for lab-on-a-chip applications. Among several methods to microstructure glass, the simplest and widely applied is the wet chemical etching (WE)....
Xi Qin, Sunyoung Park, Simon P. Duffy, Kerryn Matthews, Richard R. Ang, Tilman Todenhöfer, Hamid Abdi, Arun Azad, Jenny Bazov, Kim N. Chi, Peter C. Black and Hongshen Ma
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00226E, Paper
Separation of CTCs using resettable cell traps followed by single-cell spectral analysis.
Liviu Clime, Daniel Brassard, Matthias Geissler and Teodor Veres
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01490A, Paper
Active pneumatic pumping of liquids on lab-on-a-chip platforms by combining centrifugal fields and electromechanically controlled external pressure.
Mandy B. Esch, Jean-Matthieu Prot, Ying I. Wang, Paula Miller, Jose Ricardo Llamas-Vidales, Brian A. Naughton, Dawn R. Applegate and Michael L. Shuler
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00237K, Paper
We have developed a low-cost liver cell culture device that creates fluidic flow over a 3D primary liver cell culture that consists of multiple liver cell types, including hepatocytes and non-parenchymal cells (fibroblasts, stellate cells, and Kupffer cells).
Vincent Chan, Devin M. Neal, Sebastien G. M. Uzel, Hyeonyu Kim, Rashid Bashir and H. Harry Asada
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00222B, Paper
We demonstrate a novel technique to construct parallel assemblies of smaller muscle strips that maximize the volume of active muscle layers. In tandem with multiple muscle strips, external control through the use of optogenetics can selectively recruit muscle strips for the gradation of these forces.

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