Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
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Christopher L. Cassano, Andrew J. Simon, Wei Liu, Carl Fredrickson and Z. Hugh Fan
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00927D, Technical Innovation
Vacuum bagging technique has been adapted for fabricating thermoplastic microfluidics devices, yielding strong bonding with little channel deformation.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC01031K, Paper
In this paper, an efficient microplatform based on reverse electrodialysis, which enables high ionic flux through three dimensional nanochannel networks for high power energy generation, is demonstrated.
Marie-Eve Myrand-Lapierre, Xiaoyan Deng, Richard R. Ang, Kerryn Matthews, Aline T. Santoso and Hongshen Ma
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC01100G, Paper
Mechanism for multiplexed measurement of single red blood cell deformability to evaluate pathological cells in a heterogeneous sample.
Mais J. Jebrail, Ronald F. Renzi, Anupama Sinha, Jim Van De Vreugde, Carmen Gondhalekar, Cesar Ambriz, Robert J. Meagher and Steven S. Branda
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00703D, Paper
Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications.
Gui-Ping Zhu, Majid Hejiazan, Xiaoyang Huang and Nam-Trung Nguyen
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00885E, Paper
We investigated the phenomenon of magnetophoresis of diamagnetic microparticles suspended in a ferrofluid in a weak uniform magnetic field. No high field gradient is required for particle migration.
Hongyan Song, Ten It Wong, Anton V. Sadovoy, Lin Wu, Ping Bai, Jie Deng, Shifeng Guo, Yi Wang, Wolfgang Knoll and Xiaodong ZHOU
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00978A, Paper
We designed and fabricated two new nanostructured biosensing chips, with which the sensitive detection of prostate specific antigen (PSA) as low as 100 pg/ml can be achieved, by measuring the...
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01218F, Paper
Micropipette aspiration measures the mechanical properties of single cells. A traditional micropipette aspiration system requires a bulky infrastructure, and has a low throughput and limited potential for automation. We have...
Mayuree Chanasakulniyom, Andrew Glidle and Jonathan M Cooper
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00774C, Paper
Cell proliferation and migration are fundamental processes in determining cell and tissue behaviour. In this study we show the design and fabrication of a new single cell microfluidic structure, called...
Jan Behrens, Sean Langelier, Amgad Rezk, Gerhard Lindner, Leslie Yeo and James R. Friend
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00704B, Communication
We present a versatile and very low-power traveling SAW microfluidic sorting device able to displace and separate particles of different diameter in aqueous suspension; the travelling wave propagates through the...
Andrea Lamberti, Angelo Angelini, Serena Ricciardi and Francesca Frascella
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01027B, Technical Innovation
Herein we have proposed for the first time the exploitation of holed-designed PDMS membrane as innovative passive microarray spotter. The elastomeric membrane was fabricated taking advantage of very simple technological...
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00472H, Technical Innovation
An LED-based UV-light source producing collimated uniform illumination over a large area is built and used to fabricate PDMS microchannels with near-rectangular profiles and depths up to 300 μm.
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC01009D, Paper
A microfluidic device for studies on the germination of bacterial spores (e.g. Bacillus subtilis) based on non-specific interactions in nanoscale is presented. A decrease in the population of spores during...
zhixiong Hu, Andrew Glidle, Charles Ironside, Jonathan M Cooper and Huabing Yin
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00952E, Paper
We describe the development of an integrated, lensed Arrayed Waveguide Grating (AWG) microspectrometer for localized multiplexing fluorescence measurements. The device, which has a footprint of only 1mm wide and 1cm...
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00877D, Paper
We demonstrate that a fluorinated elastomer, called perfluoropolyether (PFPE), can be an alternative oxygen permeable elastomer for stop flow lithography (SFL) microfluidic channels. The PFPE channels can allow for the solvent-based synthesis of complex anisotropic particles, greatly enhancing the synthesis capabilities of SFL.
Megan L. Rexius-Hall, Gerardo Mauleon, Asrar B. Malik, Jalees Rehman and David T. Eddington
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC01168F, Paper
An open-well microfluidic platform generates an oxygen landscape using gas-perfused networks which diffuse across a membrane.
A. Kasukurti, C. D. Eggleton, S. A. Desai, D. I. Disharoon and D. W. M. Marr
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00863D, Paper
Non-destructive isolation of single-cells has become an important need for many biology research laboratories; however, there is a lack of easily employed and inexpensive tools.
JiSoo Park, Bo Kyeong Lee, Gi Seok Jeong, Jung Keun Hyun, C. Justin Lee and Sang-Hoon Lee
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00962B, Paper
In this paper, we developed a three-dimensional brain-on-a-chip with an interstitial level of flow. The chip contains an osmotic micropump system for providing interstitial flow and a concave microwell array for mimicking the brain's 3D cytoarchitecture.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00990H, Paper
On-chip stretching and aligning of single DNA molecules were demonstrated using microfluidic transfer of liquid interface in zigzag-shaped microgrooves.
Zhuoqing Yang, Yi Zhang, Toshihiro Itoh and Ryutaro Maeda
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00997E, Technical Innovation
We present a novel lab-on-a-tube technology, which is a combination of three-dimensional (3D) cylindrical photolithography and nanoimprint processes, for fabricating microfunctional structures on a tiny tube substrate directly.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00928B, Paper
We create a patterned structured surface in a microfluidic channel to protect supported lipid bilayers from being destroyed by air bubbles.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00798K, Paper
The shear dependence of the viscosity of shear-thinning fluids changes the dynamics of jet breakup, necessitating new approaches for its control.
Qiushu Chen, Michael Ritt, Sivaraj Sivaramakrishnan, Yuze Sun and Xudong Fan
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00872C, Communication
An optofluidic laser with a single molecular layer of gain.
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00819G, Paper
We have developed a miniaturized fluorescence detection platform for droplet based assays that can monitor multiple channels using only a single photodetector and no lenses. To accomplish this, we take advantage of the high bandwidth of electronics and encode the signal from each channel using distinct micropatterned masks.
E. Ortiz-Ortega, Marc-Antoni Goulet, Jin Wook Lee, M. Guerra-Balcázar, N. Arjona, Erik Kjeang, J. Ledesma-García and L. G. Arriaga
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC01010H, Communication
Configuration of a flow-through air-breathing nanofluidic fuel cell operated with formic acid as fuel.
Ghulam Destgeer, Byung Hang Ha, Jin Ho Jung and Hyung Jin Sung
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00868E, Paper
Submicron separation is the segregation of particles having a diameter difference of less than one micrometre.

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