Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
 
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Charles A Cartier, Aaron M Drews and Kyle Bishop
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00811A, Paper
We present a simple and effective ratcheted microfluidic mixer that uses contact charge electrophoresis (CCEP) of a micron-scale particle to rapidly mix nonpolar liquids. CCEP combines contact charging and electrostatic...
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00828F, Tutorial Review
Microfluidic or microchannel artificial lungs promise to enable a new class of truly portable, therapeutic artificial lungs through feature sizes and blood channel designs that closely mimic those found in...
 
Ruben Soares, Pedro Novo, Ana Azevedo, Pedro Fernandes, Maria Raquel Aires-Barros, Virginia Chu and João Pedro Conde
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00695J, Paper
Immunoassays are fast and sensitive techniques for analyte quantification and their use in point-of-care devices for medical, environmental, and food safety applications have potential benefits of cost, portability, and multiplexing....
 
Kelvin M. Frazier, Katherine A. Mirica, Joseph J. Walish and Timothy M. Swager
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00864B, Paper
Mechanical abrasion is an extremely simple, rapid, and low-cost method for deposition of carbon-based materials onto a substrate.
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00801D, Technical Innovation
Insulator-based dielectrophoresis enables contact-less separation and analysis of biosystems, but it is unable to operate effectively in the MHz frequency range, which is necessary for the manipulation of biological cells...
 
Ahmed Alfadhel, Bodong Li, Amir Omar Zaher, Omar Yassine and Jurgen Kosel
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00821A, Paper
A magnetic nanocomposite has been implemented as artificial hair on a giant magneto-impedance (GMI) thin film sensor for flow sensing. The 500 μm long and 100 μm in diameter pillars...
 
Lukas C Gerber, Liat Rosenfeld, Yunhan Chen and Sindy K Y Tang
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00640B, Communication
We describe the use of chemical diffusion and reaction to record temporally-varying chemical information as spatial patterns without the need for external power. Diffusion of chemicals acts as a clock,...
 
João Tiago S. Fernandes, Sandra Tenreiro, Andreia Gameiro, Virginia Chu, Tiago F. Outeiro and João P. Conde
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00756E, Paper
We report a novel platform combining a gradient generator with single-cell traps to study the expression of alpha-synuclein under different stimuli in a yeast model to investigate the mechanisms behind Parkinson's disease.
 
Gungun Lin, Denys Makarov, Michael Melzer, Wenping Si, Chenglin Yan and Oliver G. Schmidt
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00751D, Paper
A highly flexible GMR-based microfluidic analytic device was demonstrated to analyze droplets of various dimensions and different concentrations of magnetic contents.
 
Bin-Da Chan, Kutay Icoz, Wanfeng Huang, Chun-Li Chang and Cagri A. Savran
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00765D, Paper
A method to weigh individually selected biological microparticles over a dynamic range of 30 pg to 2.4 μg. The figure shows a single pollen grain specifically picked and placed on the left-hand cantilever for weighing; on the right-hand cantilever is a bead used as a reference.
 
Roman Gerbers, Wilke Foellscher, Hong Chen, Constantine Anagnostopoulos and Mohammad Faghri
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00786G, Paper
A paper-based immunosensor incorporating a microfluidic valve technology which autonomously manipulates multiple fluids to sequentially flow over a detection area.
 
Baichen Li, Lin Li, Allan Guan, Quan Dong, Kangcheng Ruan, Ronggui Hu and Zhenyu Li
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00227J, Paper
Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip infrastructures...
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00560K, Paper
Pressure-tolerant polymer-glass microfluidic reactors with excellent bonding strength have been fabricated by simultaneous solidification-bonding (SSB) method, in which a viscous and reactive matrix polymer was cast on the glass substrate...
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00804A, Paper
Abnormal DNA methylation has been associated with the development and progression of several human cancers and is a potential target for treatment. Thus, myriad technologies for the analysis of DNA...
 
Yan Pang, Hyoungsoo Kim, Zhaomiao Liu and Howard A. Stone
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00871E, Paper
We study the effect of softness of the microchannel on the process of droplet generation in two-phase flows in a T-junction microchannel.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00716F, Paper
A simple paper fluidic device provides a visual indication of blood coagulation status.
 
Joshua J. Cardiel, Ya Zhao, Lige Tonggu, Liguo Wang, Jae-Hyun Chung and Amy Q. Shen
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00610K, Communication
Schematics of microfluidic-assisted GOx immobilization in a nanogel scaffold with chronoamperometric studies for glucose sensing.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00587B, Paper
An integrated microfluidic system was developed for automatic, high-throughput screening of multiple cell lines to competitively select aptamer-based biomarkers for ovarian cancer cells.
 
Wuzhou Song, Demetri Psaltis and Kenneth B. Crozier
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00477A, Communication
We present a micro-patterned silicon structure that enables the preparation of a SERS substrate and pre-concentration of the analyte molecules.
 
YongAn Huang, Yezhou Wang, Lin Xiao, Huimin Liu, Wentao Dong and Zhouping Yin
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00762J, Paper
This paper describes the design and characterization of microfluidic serpentine antennas with reversible stretchability and designed mechanical frequency modulation (FM).
 
S. Focaroli, S. Mazzitelli, M. Falconi, G. Luca and C. Nastruzzi
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00679H, Paper
The present paper describes the production of microfluidic chips using an approach based on shrinkable biocompatible polymers (i.e. agarose) for the production of size controlled microfluidic channels.
 
Yuanjun Yan, Li Fang Ng, Li Theng Ng, Kwan Bum Choi, Jan Gruber, Andrew A. Bettiol and Nitish V. Thakor
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00494A, Paper
We present a high-throughput continuous-flow C. elegans sorting device that works based on integrated optical fiber detection and laminar flow switching.
 
Cheuk-Wing Li, Guodong Yu, Jingyun Jiang, Simon Ming-Yuen Lee, Changqing Yi, Wanqing Yue and Mengsu Yang
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00779D, Paper
Through utilizing streamline reversibility, we developed a microfluidic device for the continuous separation of free ligands from a protein–ligand complex for off-chip detection.
 
Hidehiro Oana, Kaori Nishikawa, Hirotada Matsuhara, Ayumu Yamamoto, Takaharu G. Yamamoto, Tokuko Haraguchi, Yasushi Hiraoka and Masao Washizu
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC90085E, Correction
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00424H, Paper
We present a unique method to instruct in the specific art of droplet formation using a hand-operated pressure pumping system and simple droplet generators, allowing students to form monodisperse picoliter to nanoliter droplet streams at low cost.
 

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