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Journal cover: Lab on a Chip

Lab on a Chip

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Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01223J, Communication
An impedance spectroscopy-based cell/particle position detection method in microfluidic systems is presented. A single pair of non-parallel surface microelectrodes was utilized to detect the transverse positions of particles/cells flowing in...
Gergana G. Nestorova, Karl Hasenstein, Nam Nguyen, Mark A. DeCoster and Niel D. Crews
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01421F, Paper
We report a lab-on-a-chip method for integrated extraction and analysis of mRNA from 3D cells using 130 μm in diameter stainless steel needles.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01544A, Technical Innovation
Sorting droplets on electric rails significantly improves robustness and enables multiplexing.
Helen N. Schwerdt, Min Jung Kim, Satoko Amemori, Daigo Homma, Tomoko Yoshida, Hideki Shimazu, Harshita Yerramreddy, Ekin Karasan, Robert Langer, Ann M. Graybiel and Michael J. Cima
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01398H, Paper
Cellular-scale (<10 μm) probes were developed for minimally invasive, subsecond, and multi-site monitoring of neurochemicals in rat brain.
Koen J.H.G. de Wijs, Chengxun Liu, Alexandra Dusa, Dries Vercruysse, Bivragh Majeed, Deniz Sabuncuoglu Tezcan, Kamil Blaszkiewicz and Liesbet Lagae
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01560C, Paper
Safe, high-rate and cost-effective cell sorting is important for clinical cell isolation. However, commercial fluorescence-activated cell sorters (FACS) are expensive and prone to aerosol-induced sample contamination. Here we report a...
Thomas F Scherr, Sparsh Gupta, David Wright and frederick haselton
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01580H, Paper
Many countries are shifting their efforts from malaria control to disease elimination. New technologies will be necessary to meet the more stringent demands of elimination campaigns, including improved quality control...
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01489E, Paper
The microdroplet megascale detector (μMD) generates and detects the fluorescence of millions of droplets per second using a cellphone camera.
Khashayar Khoshmanesh, Shi-Yang Tang, Jiu Yang Zhu, Samira Schaefer, Arnan Mitchell, Kourosh Kalantar-zadeh and Michael D. Dickey
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00046D, Tutorial Review
This review discusses the opportunities provided by gallium liquid metal alloys for making various microfluidic components.
Collin B. Eaker, Ishan D. Joshipura, Logan R. Maxwell, Jason Heikenfeld and Michael D. Dickey
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01500J, Paper
Electrowetting uses voltage to manipulate small volumes of fluid for applications including lab-on-a-chip and optical devices.
Adele De Ninno, Vito Errico, Francesca Romana Bertani, Luca Businaro, Paolo Bisegna and Federica Caselli
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01516F, Paper
We present an original five-electrode coplanar chip enabling accurate particle sizing without the need for focusing.
Jinsoo Park, Jin Ho Jung, Ghulam Destgeer, Husnain Ahmed, Kwangseok Park and Hyung Jin Sung
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01405D, Paper
Precise control over droplet position within a microchannel is fundamental to droplet microfluidic applications. This article proposes acoustothermal tweezer for the control of droplet position, which is based on thermocapillary...
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01577H, Critical Review
Microfluidic paper-based analytical devices (μPADs) have emerged as a promising diagnostic platform a decade ago. In contrast to highly active academic developments, their entry into real-life applications is still very...
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01583B, Tutorial Review
Chemical communication leading to synchronization and collective behaviour of dynamic elements, such as cell colonies, is a widespread phenomenon with biological, physical and chemical importance. Such synchronization between elements proceeds...
Yi Zhang and Nam-Trung Nguyen
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00025A, Critical Review
A magnetic digital microfluidic platform manipulates droplets on an open surface.
Zhiming Zhai, Fengqiu Zhang, Xiang-Yu Chen, Jie Zhong, Gang Liu, Yang-Chao Tian and Qing Huang
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00053G, Paper
This paper reports synthesis and application of biocompatible and sensitive SERS nanoparticles for the study of uptake of nanoparticles into living cells in a microfluidic chip through surface enhanced Raman...
Gang Zhao, Zhiguo Zhang, Yuntian Zhang, Zhongrong Chen, Dan Niu, Yunxia Cao and Xiaoming He
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01532H, Paper
Accurate characterization of the cell membrane transport properties of human oocytes is of great significance to reproductive pharmacology, fertility preservation, and assisted reproduction. However, the commonly used manual method for...
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00006E, Paper
Fundamental and critical unit operations (creating, transporting, splitting and merging of droplets) for digital (droplet-based) microfluidic circuits have been established using dielectrowetting.
Adrian M. Nightingale, Gareth W. H. Evans, Peixiang Xu, Byung Jae Kim, Sammer-ul Hassan and Xize Niu
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01479H, Paper
We describe a highly robust method to generate droplets using peristaltically-pumped anti-phased oil/aqueous flows with droplet size, frequency and composition specifiable in the pump design.
Ali K. Yetisen, Nan Jiang, Ali Tamayol, Guillermo U. Ruiz-Esparza, Yu Shrike Zhang, Sofía Medina-Pando, Aditi Gupta, James S. Wolffsohn, Haider Butt, Ali Khademhosseini and Seok-Hyun Yun
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01450J, Paper
This article describes a paper-based microfluidic system that quantifies the concentrations of tear electrolytes using a smartphone-based reader.
Thomas H. Linz, W. Hampton Henley and J. Michael Ramsey
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01415A, Paper
Encoding beads with dyes of differing photobleaching properties adds a novel dimension to bead encoding schemes.
J. Park, M. L. Salmi, W. W. A. Wan Salim, A. Rademacher, B. Wickizer, A. Schooley, J. Benton, A. Cantero, P. F. Argote, M. Ren, M. Zhang, D. M. Porterfield, A. J. Ricco, S. J. Roux and J. L. Rickus
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01370H, Paper
A device designed for space flight measures the longest continuous observation of a plant cell's calcium response to hypergravity made to date.
Timothy Quang Vu, Ricardo Miguel Bessa de Castro and Lidong Qin
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01367H, Critical Review
From themed collection Lab on a Chip: Recent Review Articles
This review will cover how cell–cell microfluidic devices have made advancements in fields like immunology, neuroscience, ophthalmology, cancer research, and more.
Adam L. Nekimken, Holger Fehlauer, Anna A. Kim, Sandra N. Manosalvas-Kjono, Purim Ladpli, Farah Memon, Divya Gopisetty, Veronica Sanchez, Miriam B. Goodman, Beth L. Pruitt and Michael Krieg
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01165A, Paper
A new microfluidic tool for simultaneous immobilization, force delivery and high resolution imaging of neuronal activity in living Caenorhabditis elegans.
Claudiu A. Stan, Audrey K. Ellerbee, Laura Guglielmini, Howard A. Stone and George M. Whitesides
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC90014G, Correction
From themed collection Open access articles recently published in Lab on a Chip
Yahui Yang, Siyuan Xing, Zecong Fang, Ruya Li, Helen Koo and Tingrui Pan
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01522K, Paper
Here we show for the first time a wearable microfluidic platform, named as digital droplet flowmetry (DDF), implemented on all-textile materials for real-time measurement of perspiration rates, via converting continuous flow into discrete droplets with identical volumes and assessing the flow rates by an electronic counting circuitry.

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69 citations
In this paper, a review is carried out of how 3D printing helps to improve the fabrication of microfluidic devices, the 3D printing technologies currently used for fabrication and the future of 3D printing in the field of microfluidics.
DOI: 10.1039/C5LC00685F
Published: 22 Jul 2015
67 citations
We established a microfluidic four-organ-chip for interconnected long-term co-culture of human intestine (1), liver (2), skin (3) and kidney (4) equivalents.
DOI: 10.1039/C5LC00392J
Published: 13 May 2015
25 citations
3D printing has the potential to significantly change the field of microfluidics.
DOI: 10.1039/C6LC00284F
Published: 25 Apr 2016

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