Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
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Micheal Leser, Jonathan Pegan, Mohammed El Makkaoui, Joerg C. Schlatterer, Michelle Khine, Matt Law and Michael Brenowitz
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01288G, Technical Innovation
The structure of macromolecules and their complexes dictate their biological function. In “footprinting”, the solvent accessibility of the residues that constitute proteins, DNA and RNA can be determined from their...
Frank Schwemmer, Steffen Zehnle, Daniel Mark, Felix von Stetten, Roland Zengerle and Nils Paust
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01269K, Paper
Accurate timing of microfluidic operations is essential for the automation of complex laboratory workflows, in particular for the supply of sample and reagents. Here we present a new unit operation...
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01266F, Paper
This paper describes an underwater micro propulsion principle where a gaseous bubble trapped in a suspended microchannel and oscillated by an external acoustic excitation generates a propelling force. The propelling...
R. E. Gerver, R. Gómez-Sjöberg, B. C. Baxter, K. S. Thorn, P. M. Fordyce, C. A. Diaz-Botia, B. A. Helms and J. L. DeRisi
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90018B, Correction
Hyunjoo Jenny Lee, Yoojin Son, Jeongyeon Kim, Changjoon Justin Lee, Eui-Sung Yoon and Il-Joo Cho
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01321B, Paper
Multi-functional neural probes integrated with various stimulation modalities are becoming essential tools in neuroscience to study brain more effectively. In this paper, we present a new multi-functional neural probe that...
Kyoung G. Lee, Sujeong Shin, Byeong Il Kim, Nam Ho Bae, Moon-Keun Lee, Seok-Jae Lee and Tae Jae Lee
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01473A, Technical Innovation
Perfect sealing of heterogeneous microstructures in plastic-based microfluidic devices is significant and urgent challenges to apply them in various microfluidic-based applications including biosensing, biofiltering, chemical reactors and lab-on-a-chip. In this...
Robert Lin, Arunan Skandarajah, Rachel E. Gerver, Hector D. Neira, Daniel A. Fletcher and Amy E. Herr
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01370K, Paper
Antibodies against the hepatitis C virus are detected in human sera using the CellScope-enabled electrophoretic barcode assay.
Miao Yu, Youmin Hou, Hongbo Zhou and Shuhuai Yao
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01480D, Paper
Preconcentration of biomolecules by electrokinetic trapping at the nano/microfluidic interface has been extensively studied due to its significant concentration efficiency. Conventionally, the sample preconcentration takes place in continuous flow and...
N. Gopalakrishnan, R. Hannam, G. P. Casoni, D. Barriet, J. M. Ribe, M. Haug and Ø. Halaas
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01438C, Paper
Immunity on a chip: modeling and designing immune reactions in vitro to study immune responses on a chip as well as unraveling physiological processes under a microscope.
Hsieh-Fu Tsai, Yi-Ching Tsai, Sharon Yagur-Kroll, Noa Palevsky, Shimshon Belkin and Ji-Yen Cheng
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01189A, Paper
This is a portable system for water contamination monitoring. Using live bacterial cells as bioreporters, we integrate temperature control, microfluidic sample introduction, bioluminescence detection, and recording software into a complete system.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01127A, Paper
A stacking flow platform for single-step detection of a target antibody in salivary fluid with improved flow uniformity and reduced background.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01070A, Paper
Microfluidic platform for generating dynamic profile of cell stimuli for non-adherent cells.
S. Durán, S. Novo, M. Duch, R. Gómez-Martínez, M. Fernández-Regúlez, A. San Paulo, C. Nogués, J. Esteve, E. Ibañez and J. A. Plaza
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01299B, Paper
We develop chip-on-a-cell barcodes featuring silicon nanowires as nanoscale attachment to label living mouse embryos.
Bhushan J. Toley, Jessica A. Wang, Mayuri Gupta, Joshua R. Buser, Lisa K. Lafleur, Barry R. Lutz, Elain Fu and Paul Yager
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01155D, Paper
A versatile, powerless, valving and automation toolkit for paper microfluidic devices that uses absorbent expanding elements as actuators is presented.
Susan H. Roelofs, Bumjoo Kim, Jan C. T. Eijkel, Jongyoon Han, Albert van den Berg and Mathieu Odijk
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01410C, Paper
We demonstrate capacitive deionization in a microfluidic chip and monitor the salt concentration between the desalination electrodes in real-time.
S. Xiong, L. K. Chin, K. Ando, T. Tandiono, A. Q. Liu and C. D. Ohl
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01184H, Paper
The transformation process of a bubble to a droplet is experimentally demonstrated by focusing a pulse laser near a gas–liquid interface in a nanofluidic channel.
Seungjeong Song, Minseok S. Kim, Jaeyeon Lee and Sungyoung Choi
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01417K, Communication
This communication presents a microfluidic method for size-based cell sorting, which provides a simple and robust approach for cell cycle synchronization by manual and stand-alone operation.
Tie Yang, Petra Paiè, Giovanni Nava, Francesca Bragheri, Rebeca Martinez Vazquez, Paolo Minzioni, Manuela Veglione, Maira Di Tano, Chiara Mondello, Roberto Osellame and Ilaria Cristiani
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01496K, Communication
We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism, based on optical forces, does not hamper...
Daniela Gallerano, Eva Wollmann, Christian Lupinek, Thomas Schlederer, Daniel Ebner, Christian Harwanegg, Katarzyna Niespodziana, Klaus Schmetterer, Winfried Pickl, Elisabeth Puchhammer-Stöckl, Elopy N Sibanda and Rudolf Valenta
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01510J, Paper
We used the microarray technology to develop chips containing a comprehensive set of proteins and peptides covering the proteome of HIV-1 clade C, which is the HIV-1 subtype that causes...
Radin Tahvildari, Eric Beamish, Vincent Tabard-Cossa and Michel Godin
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01366B, Technical Innovation
Nanopore arrays are fabricated by controlled dielectric breakdown (CBD) in solid-state membranes integrated within polydimethylsiloxane (PDMS) microfluidic devices. This technique enables the scalable production of independently addressable nanopores. By confining...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01246A, Critical Review
This review surveys the leading approaches for sorting cells in microfluidic devices and organizes those technologies by the many physical mechanisms exploited for sorting.
Hao Wang, Chia-Hung Chen, Zhuolin Xiang, Ming Wang and Chengkuo Lee
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01451K, Paper
We developed a novel gradient generator to achieve long range and linear chemical gradients with a dynamic control function.
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C4LC01384K, Paper
The nematode Caenorhabditis elegans is an important model organism in research on neuroscience and development because of its stereotyped anatomy, relevance to human biology, and ease of culture and genetic...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90011E, Commentary
Tony Jun Huang provides a commentary to accompany the article by Whitesides et al. (DOI: 10.1039/C4LC01161A).
K. M. Kovach, M. A. LaBarbera, M. C. Moyer, B. L. Cmolik, E. van Lunteren, A. Sen Gupta, J. R. Capadona and J. A. Potkay
Lab Chip, 2015, Advance Article
DOI: 10.1039/C4LC01284D, Paper
We describe the first microfluidic artificial lung featuring a hemocompatible surface coating and a biomimetic blood path and its application in an in vitro and in vivo model.

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