Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in MEDLINE
 
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Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00784K, Critical Review
Stimulus-responsive polymers are particularly promising candidates to tackle the remaining challenges in nanofluidic devices regarding addressable ‘smart’ switches and actuators.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00910J, Paper
The pumping-lid method enables equipment-free, controlled generation of pressures using disposable parts that can be integrated with existing microfluidic devices.
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00785A, Paper
The number of microfluidic strategies aimed at separating particles or cells of a specific size within a continuous flow system continues to grow. The wide array of biomedical and other...
 
Tadej Kokalj, Younggeun Park, Matjaž Vencelj, Monika Jenko and Luke P. Lee
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00920G, Technical Innovation
We report disposable, autonomous, easy to use and fabricate, self-powered microfluidic pump suitable for POC devices.
 
Qiang Zhang, Peiran Zhang, Yetian Su, Chunbo Mou, Teng Zhou, Menglong Yang, Jian Xu and Bo Ma
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00833B, Technical Innovation
We develop an easy-to-use, low-cost and on-demand microfluidic flow controlling method based on capillary-tuned solenoid valve suction without any pressure source.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00645C, Communication
We have developed a versatile and facile microfluidic method for forming magnetic decentered core–shell microcapsules, which are temperature-responsive and could burst release directly toward a target point.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00879K, Paper
Particle counting finds many industrial applications especially in medical healthcare. Cell differentiation in coincidence occurrences is essential for accurate cell enumeration for specific cell type counting. In this paper, we have characterized the coincidence detection with cell differentiation using a microfluidic impedance biochip.
 
Martin Dean Brennan, Megan L. Rexius, Laura Jane Elgass and David T Eddington
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00853G, Critical Review
Cellular function and behavior are affected by the partial pressure of O2, or oxygen tension, in the microenvironment. The level of oxygenation is important, as it is a balance of...
 
R. R. G. Soares, P. Novo, A. M. Azevedo, P. Fernandes, M. R. Aires-Barros, V. Chu and J. P. Conde
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00695J, Paper
We present a device consisting of two modules integrated in series: the first performs an aqueous two-phase extraction (ATPE) of matrix contaminants and analyte pre-concentration, and the second an immunoassay for quantification of the analyte.
 
Vahid Farmehini, Ali Rohani, Yi-Hsuan Su and Nathan S. Swami
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00801D, Technical Innovation
To enable contact-less dielectrophoretic manipulation of biosystems in the MHz range, we present the design principles for a wideband power amplifier that eliminates parasitic DC and harmonic distortions.
 
A. Alfadhel, B. Li, A. Zaher, O. Yassine and J. Kosel
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00821A, Paper
We present a permanent magnetic nanocomposite cilia sensor for flow detection with high sensitivity and low power consumption.
 
Séverine Le Gac, Johan Bomer, Alexander Prokofyev and Albert van den Berg
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00921E, Technical Innovation
We report a wafer-scale fabrication process for the production of glass-FEP-glass microdevices using UV-curable adhesive (NOA81) as gluing material, which is applied using a novel “spin & roll” approach. Devices...
 
C. Witte, J. Reboud, R. Wilson, J. M. Cooper and S. L. Neale
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00749B, Paper
Acoustophoretic particle manipulation system consisting of surface acoustic waves coupled into a disposable superstrate that facilitates simple assembly.
 
Jin-Oh Kim, Heejin Kim, Dong-Hyeon Ko, Kyoung-Ik Min, Do Jin Im, Soo-Young Park and Dong-Pyo Kim
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00748D, Paper
A photocurable and viscous fluoropolymer with chemical stability is a highly desirable material for fabrication of microchemical devices.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00730A, Paper
This paper details a method of fabricating nonplanar 3D paper microfluidic circuits utilizing patterned aerosol adhesives.
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00939H, Tutorial Review
A tutorial review focusing on the theory, design, application and progress of deterministic lateral displacement since invention ten years ago.
 
Alvaro Jose Conde, Milena Batalla, Belén Cerda, Olga Mykhaylyk, Christian Plank, Osvaldo Podhajcer, Juan Martín Cabaleiro, Rossana Madrid and Lucia Policastro
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00839A, Paper
We present a low-cost, portable microfluidic platform that uses laminated poly-methylmethacrylate chips, peristaltic micropumps and LEGO® Mindstorms components for the generation of magnetoliposomes that does not require extrusion steps. Combinations...
 
Shashi Ranjan, Kerwin Kwek Zeming, Roland Jureen, Dale Fisher and Yong Zhang
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00578C, Paper
Microfluidic devices with different shape pillar arrays were designed for separation of spherical and non-spherical bioparticles such as red blood cells (RBC) and bacteria, based on deterministic lateral displacement (DLD).
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00895B, Technical Innovation
In this work we describe a novel and simple self-assembly of colloidal silica beads to create nanofluidic junction between two microchannels. The nanoporous membrane was used to induce ion concentration...
 
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00608A, Paper
We present a real-rock micromodel approach whereby microfluidic channels are fabricated in a naturally occurring mineral substrate. The method is applied to quantify calcite dissolution which is relevant to oil/gas...
 
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00560K, Paper
Polymer-glass microreactors fabricated by the simultaneous solidification-bonding technique are transparent and pressure-tolerant for flash chemistry under high pressure conditions.
 
Hardik J Pandya, Wenjin Chen, Lauri A Goodell, David J Foran and Jaydev Desai
Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00594E, Paper
The mechanical properties of tissue change significantly during the progression from healthy to malignant. Quantifying the mechanical properties of breast tissue within the tumor microenvironment can help to delineate benign...
 
Wonmo Kang, Juan P. Giraldo-Vela, S. Shiva P. Nathamgari, Tammy McGuire, Rebecca L. McNaughton, John A. Kessler and Horacio D. Espinosa
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00721B, Paper
A novel microfluidic device for long term on-chip cell culture to support stem cell differentiation and transfection of postmitotic neurons in vitro utilizing localized electroporation.
 
A. A. P. Trichet, J. Foster, N. E. Omori, D. James, P. R. Dolan, G. M. Hughes, C. Vallance and J. M. Smith
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00817K, Paper
This article presents the open-access optical microcavities as a novel label-free optofluidic refractive index sensor with femtoliter detection volume.
 
P. Y. Liu, L. K. Chin, W. Ser, T. C. Ayi, P. H. Yap, T. Bourouina and Y. Leprince-Wang
Lab Chip, 2014, Advance Article
DOI: 10.1039/C4LC00783B, Paper
An on-chip optofluidic imaging system is innovated to measure the biophysical signatures of single waterborne bacteria.
 

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