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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.748 24 Issues per Year Indexed in Medline
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Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00294J, Paper
We reveal a method to transport, disperse and order dense assemblies of magnetically responsive colloids on a surface within seconds and with velocities of mm s−1.
W. Zhang, Y. Gu, Y. Hao, Q. Sun, K. Konior, H. Wang, J. Zilberberg and W. Y. Lee
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00341E, Paper
We present a multipurpose 96-well plate-based perfusion culture device for tissue and tumor microenvironment replication.
Carlos Escobedo, Sebastian C Bürgel, Simon Kemmerling, Nora Sauter, Thomas Braun and Andreas Hierlemann
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00552C, Paper
On-chip lysis is required in many lab-on-chip applications involving cell studies. In these applications, the complete disruption of the cellular membrane and a high lysis yield is essential. Here, we...
Nicholas J. Mozdzierz, Kerry R. Love, Kevin S. Lee, Harry L. T. Lee, Kartik A. Shah, Rajeev Ram and J Christopher Love
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00443H, Communication
We present an integrated microfluidic bioreactor for fully continuous perfusion cultivation of suspended microbial cell cultures. This system allowed continuous and stable heterologous protein expression by sustaining the cultivation of...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00326A, Paper
We present an on-chip liquid routing technique intended for application in well-based microfluidic systems that require long-term active pumping at low to medium flowrates.
Evgeny S. Asmolov, Alexander L. Dubov, Tatiana V. Nizkaya, Alexander J. C. Kuehne and Olga I. Vinogradova
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00310E, Paper
We propose a concept of fractionation of micron-sized particles in a microfluidic device with a bottom wall decorated by superhydrophobic stripes.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00342C, Technical Innovation
We report a novel reversible bonding method for microfluidic devices using gecko-inspired dry adhesives that result in an instant high-strength bond suitable for pressure driven flows. The concept also provides for viable stick and play interconnections.
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00265F, Frontier
Recent advances in microfluidic actuation and micro-object manipulation by surface acoustic waves have been reviewed.
Youchun Xu, He Yan, Yan Zhang, Kewei Jiang, Ying Lu, Yonghong Ren, Hui Wang, Shan Wang and Wanli Xing
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00244C, Paper
A reversible centrifugation-based multiplex PCR chip is constructed and applied to identify 8 pathogenic bacteria and 13 drug-resistance genes.
Xiaohua Huang, Matthew T Walsh, Alexander Hsiao, Ho Suk Lee and Zhixia Liu
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00445D, Paper
Accurate measurement of RNA transcripts from single cells will enable the precise classification of cell types and characterization of the heterogeneity in cell populations that play key roles in normal...
Daniel Czurratis, Yvonne Beyl, Alexander Grimm, Thomas Brettschneider, Sven Zinober, Franz Laermer and Roland Zengerle
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00510H, Paper
Liquids on-chip describes a reagent storage concept for disposable pressure driven Lab-on-Chip (LoC) devices, which enables liquid storage in reservoirs without additional packaging. On-chip storage of liquids can be considered...
Hongbo Zhu, Robert Nidetz, Menglian Zhou, Jiwon Lee, Sanketh Buggaveeti, Katsuo Kurabayashi and Xudong Fan
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00328H, Paper
This is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available.
Detlev Belder, Tim Arne Meier, Elisabeth Poehler, Heinz-Georg Jahnke, Andrea Robitzki, Erik Beckert, Oliver Pabst and Falk Kemper
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00397K, Technical Innovation
A microfluidic chip approach utilising integrated electrically connected stationary SERS targets based on inkjet-printed silver nanoparticles is presented. It enables multiple interference-free consecutive surface-enhanced Raman measurements inside chip channels by...
Russell Cole, Niek de Lange, Zev Gartner and Adam Ross Abate
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00333D, Technical Innovation
Multicolour fluorescence detection is often necessary in droplet microfluidics, but typical detection systems are complex, bulky, and expensive. We present a compact and modular detection system capable of sub-nanomolar sensitivity...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00285K, Paper
Instantaneous and robust bonding of various non-silicon substrates with PDMS was realized at room temperature within 12 to 17 min by mercaptosilane coating.
Jinzhou Yuan, Jessie Zhou, David M. Raizen and Haim H. Bau
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00305A, Paper
This paper describes the design, fabrication, characterization, and applications of a high-throughput motility-based sorter for microswimmers such as C. elegans.
Justin D. Besant, Edward H. Sargent and Shana O. Kelley
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00375J, Paper
Concentrating bacteria in nanoliter culture chambers enables rapid electrochemical antibiotic susceptibility testing on-chip.
David M. Cate, Scott D. Noblitt, John Volckens and Charles S. Henry
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00364D, Paper
Multiplexed detection of Ni, Cu, and Fe from particulate air pollution with paper-based microfluidic devices is described. Analysis is simple, inexpensive, and does not require any external instrumentation.
Mun-Bum Song, Hyou-Arm Joung, Young Kyoung Oh, Young Deok Ahn, Kwonyoung Jung and Min-Gon Kim
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00521C, Paper
This article describes a new method, referred to as "tear-off patterning," for patterning nitrocellulose (NC) membranes in order to fabricate NC-based point-of-care (POC) diagnostic devices. Paper-based microfluidic sensors usually employ...
Nitesh Nama, Rune Barnkob, Zhangming Mao, Christian J. Kähler, Francesco Costanzo and Tony Jun Huang
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00231A, Paper
We present a numerical study of the acoustophoretic motion of particles suspended in a liquid-filled PDMS microchannel on a lithium niobate substrate acoustically driven by surface acoustic waves.
Ching-Hui Lin, Yi-Hsing Hsiao, Hao-Chen Chang, Chuan-Feng Yeh, Cheng-Kun He, Eric M. Salm, Chihchen Chen, Ing-Ming Chiu and Chia-Hsien Hsu
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00541H, Paper
In vitro culture of single cells facilitates biological studies by deconvoluting complications from cell population heterogeneity. However, there is still a lack of simple yet high-throughput method to perform single...
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00503E, Paper
A user-friendly microfluidic chamber produces a passive, stable gradient of soluble cues for imaging and quantification of axon turning.
Ramya Veerubhotla, Aditya Bandopadhyay, Debabrata Das and Suman Chakraborty
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC00211G, Communication
We present a low-cost, disposable microbial fuel cell fabricated on a paper based platform, having a start-up time of 10 s.
Majid Hejazian and Nam-Trung Nguyen
Lab Chip, 2015, Accepted Manuscript
DOI: 10.1039/C5LC00427F, Paper
We report magnetic manipulation of non-magnetic particles suspended in diluted ferrofluid. Diamagnetic particles were introduced into a circular chamber to study the extent of their deflection under the effect of...
Andy K. Tay, Manjima Dhar, Ivan Pushkarsky and Dino Di Carlo
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC90060C, Highlight
Acoustic separation of circulating tumor cells – BLAST-ing large cargo into cells at high-throughput – Magnetic control of intracellular protein distribution.

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