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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.586 24 Issues per Year Indexed in Medline
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Yu-Chih Chen, Zhixiong Zhang, Shamileh Fouladdel, Yadwinder Deol, Patrick N Ingram, Sean McDermott, Ebrahim Azizi, Max S Wicha and Euisik Yoon
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00062B, Paper
Considerable evidence suggests that cancer stem-like cells (CSCs) are critical in tumor pathogenesis, but their rarity and transience has led to much controversy about their exact nature. Although CSCs can...
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00751A, Paper
Here, we introduce a simple and fast method for bonding poly(dimethylsiloxane) (PDMS) silicone elastomer to different plastics. In this technique, surface modification and subsequent bonding processes are performed at room...
Quang D. Tran, Tian Fook Kong, Dinglong Hu, Marcos and Raymond H. W. Lam
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00615A, Paper
Isolation of rare cells, such as circulating tumor cells, has been challenging because of their low abundance and limited timeframes of expressions of relevant cell characteristics. In this work, we...
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00473C, Paper
From themed collection 2016 Lab on a Chip Emerging Investigators
Rapid liquid switching on a microfluidic probe enables localized multi-step surface reactions.
Yukun Ren, Jiangwei Liu, Weiyu Liu, Qi Lang, Ye Tao, Qingming Hu, Likai Hou and Hongyuan Jiang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00485G, Paper
We propose a novel continuous-flow microfluidic particle concentrator with a specified focusing-particle number ratio (FR) at different channel outlets using induced-charge electroosmosis (ICEO).
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00289G, Paper
Low-cost, ultraflexible microfluidic cloth-based analytical devices (μCADs) for wireless electrochemiluminescence based on closed bipolar electrodes.
David Conchouso, Garret McKerricher, Armando Arpys Arevalo Carreno, David Agustin Castro, Atif Shamim and Ian G. Foulds
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00693K, Technical Innovation
Scaled-up production of microfluidic droplets, through the parallelization of hundreds of droplet generators, has received a lot of attention to bring novel multiphase microfluidics research to industrial applications. However, apart...
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00737F, Tutorial Review
This review shows the recent advances and state-of-the-art in paper-based analytical devices (PADs) through the analysis of their integration with microfluidics and LOC micro and nanotechnologies, electrochemical / optical detections...
Dolors Pla, Marc Salleras, Alex Morata, Iñigo Garbayo, Marta Gerbolès, Neus Sabaté, Nuria J. Divins, Albert Casanovas, Jordi Llorca and Albert Tarancon
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00583G, Paper
A novel design of a silicon-based micro-reformer for onboard hydrogen generation from ethanol is presented in this work. The micro-reactor is fully fabricated with mainstream MEMS technology and consists of...
Kaitlyn Hood, Soroush Kahkeshani, Dino Di Carlo and Marcus Roper
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00314A, Paper
We experimentally measured the trajectories of particles undergoing microfluidic inertial focusing, and show that they can be predicted by an asymptotic theory with no unmeasured parameters.
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00703A, Paper
The following is a report on an experimental technique that allows one to quantify and map the velocity field with very high resolution and simple equipment in large 2D devices.
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00561F, Paper
Here we developed an integrated volumetric bar-chart chip (IV-Chip) technology by integration of our previous V-Chip with a fluid handling design to generate an instrument-free POC device and greatly reduce...
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00518G, Paper
The lateral-flow immunoassay (LFA) is a well-established diagnostic technology that has recently seen significant advancements due in part to the rapidly expanding fields of paper diagnostics and paper-fluidics. As LFA-based...
Pamuditha N. Silva, Zaid Atto, Romario Regeenes, Uilki Tufa, Yih Yang Chen, Warren Che Wor Chan, Allen Volchuk, Dawn M. Kilkenny and Jonathan V. Rocheleau
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00345A, Paper
Tissues are challenging to genetically manipulate due to limited penetration of viral particles resulting in low transduction efficiency. We are particularly interested in expressing genetically-encoded sensors in ex vivo pancreatic...
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00477F, Paper
Using a single primitive (A., B.) we created an algorithmically scalable (D.) reconfigurable routing fabric (E.) for continuous-flow microfluidic devices capable of arbitrary routing.
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00619A, Technical Innovation
This is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available.
Nuno M Reis, Jeremy Pivetal, Ana Luisa Loo-Zazueta, Joao Barros and Alexander Daniel Edwards
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00332J, Paper
A new microfluidic concept for multi-analyte testing in a dipstick format is presented, termed “Lab-on-a-Stick”, that combines the simplicity of dipstick tests with the high performance of microfluidic devices. Lab-on-a-Stick...
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00647G, Paper
Investigation of cell signaling pathways is important for the study of pathogenesis of cancer. However, the related operations used in these studies are time consuming and labor intensity. Thus, it...
Shwathy Ramesan, Amgad R. Rezk, Kai Wei Cheng, Peggy P. Y. Chan and Leslie Y. Yeo
Lab Chip, 2016, Advance Article
DOI: 10.1039/C5LC00937E, Paper
Dynamically tuneable concentration gradients are demonstrated in a thread-based microfluidic network that can be embedded in a three-dimensional hydrogel construct to mimic in vivo tissue microenvironments.
Leila Montazeri, Shahin Bonakdar, Mojtaba Taghipour, Philippe Renaud and Hossein Baharvand
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00437G, Communication
We present an easy, durable method to generate a partially hydrophilic/hydrophobic poly(dimethylsiloxane) (PDMS) microfluidic device.
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00461J, Paper
We have developed an expandable modular body-on-a-chip design that allows for a plug-and-play approach.
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00662K, Critical Review
From themed collection Lab on a Chip Recent HOT Articles
Microfluidic technologies have miniaturized a variety of biomedical applications, and these chip-based systems have several significant advantages over their large-scale counterparts. Recently, this technology has been used for automating labor-intensive...
Kejie Chen, Mengxi Wu, Feng Guo, Peng Li, Chung Yu Chan, Zhangming Mao, Sixing Li, Liqiang Ren, Rui Zhang and Tony Jun Huang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00444J, Paper
A 3D acoustic tweezers platform is developed to fabricate size-controllable multicellular spheroids in a rapid and high-throughput manner, utilizing the acoustic Gor'kov potential field and microstreaming.
Gabriella Lestari, Alinaghi Salari, Milad Abolhasani and Eugenia Kumacheva
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00597G, Paper
Liquid–liquid extraction is an important separation and purification method; however, it faces a challenge in reducing the energy consumption and the environmental impact of solvent (extractant) recovery. An oscillatory microfluidic platform is proposed to study reactive liquid–liquid extraction involving switchable solvents and carbon dioxide gas.
Mehdi Rafeie, Jun Zhang, Mohsen Asadnia, Weihua Li and Majid Ebrahimi Warkiani
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00713A, Paper
Blood and blood products are critical components of health care. Blood components perform distinct functions in human body and thus the ability to efficiently fractionate blood into its individual components...

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29 citations
DOI: 10.1039/C5LC00685F
Published: 22 Jul 2015
71 citations
DOI: 10.1039/C4LC00128A
Published: 28 May 2014

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