Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 5.67 24 Issues per Year Indexed in MEDLINE
 
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Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50431J, Paper
We present a smartphone based platform for rapid and accurate colorimetric detection of biomarkers in sweat and saliva.
 
David J. Collins, Tuncay Alan, Kristian Helmerson and Adrian Neild
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50372K, Paper
Surface acoustic waves (SAW) are shown to produce individual water-in-oil droplets on-demand, with additional controlled pre-concentration and encapsulation of cells.
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50151E, Paper
We have used a suspended MT–kinesin assay to compare the effect of different tau isoforms and mutations on the kinesin velocity.
 
Trieu Nguyen, Yanbo Xie, Lennart J. de Vreede, Albert van den Berg and Jan C. T. Eijkel
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC41232F, Paper
We show an experimental demonstration of the effect of high concentrations of polymer added to the working solution in a microchannel and how it greatly enhances the energy conversion efficiency from the pressure induced streaming current.
 
Ashutosh Agarwal, Josue Adrian Goss, Alexander Cho, Megan L. McCain and Kevin Kit Parker
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50350J, Paper
We present the design of a higher throughput “heart on a chip” which utilizes a semi-automated fabrication technique to process sub millimeter sized thin film cantilevers of soft elastomers. Anisotropic...
 
Tzer Hwai Gilbert Thio, Fatimah Ibrahim, Wisam Al-Faqheri, Jacob Moebius, Noor Sakinah Khalid, Norhayati Soin, Maria Kahar Bador Abdul Kahar and Marc Madou
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC00004D, Paper
We present a novel push and pull bi-directional pumping mechanism on a centrifugal microfluidic CD platform. The thermally actuated pumping mechanism allows for implementation of advanced applications such as valveless switch pumping.
 
Ling Yu, Shu Rui Ng, Yang Xu, Hua Dong, Ying Jun Wang and Chang Ming Li
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC00052D, Tutorial Review
This review surveys and discusses the progresses of nanotechnologies-based techniques to achieve isolation and characterization of viable circulating tumor cells.
 
John Wikswo, Erica Curtis, Zachary Eagleton, Brian Evans, Ayeeshik Kole, Lucas Hofmeister and William Matloff
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50243K, Critical Review
This is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available.
 
Krzysztof Churski, Michal Nowacki, Piotr M Korczyk and Piotr Garstecki
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50340B, Paper
This report provides practical guidelines for the use of inexpensive electromagnetic valves characterized by large (tens to hundreds of uL) dead volumes for generation of small (nL) droplets on demand...
 
Brendon Baker, Britta Trappmann, Sarah C Stapleton, Esteban Toro and Christopher S. Chen
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50493J, Paper
Gradients of diffusive molecules within 3D extracellular matrix (ECM) are essential in guiding many processes such as development, angiogenesis, and cancer. The spatial distribution of factors that guide these processes...
 
Sarah Louise Perry, Sudipto Guha, Ashtamurthy Pawate, Amrit Bhaskarla, Vinayak Agarwal, Satish Nair and Paul Kenis
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50276G, Communication
We report a microfluidic approach for de novo protein structure determination via crystallization screening and optimization, as well as on-chip X-ray diffraction data collection. The structure of phosphonoacetate hydrolase (PhnA)...
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50332A, Paper
This article demonstrates the use of silver/silver chloride electrodes in a salt-bridge system for bubble-free actuation in chip-based electrophoresis systems.
 
Fumisato Ozawa, Kosuke Ino, Toshiharu Arai, Javier Ramón-Azcón, Yasufumi Takahashi, Hitoshi Shiku and Tomokazu Matsue
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50455G, Paper
In this study, we developed a novel method for fabricating microwell arrays constructed from alginate gels. The alginate gel microwells were used for three-dimensional (3D) cell culture.
 
Brett Kirkland, Zhibin Wang, Peipei Zhang, Shin-ichiro Takebayashi, Steven Lenhert, David M. Gilbert and Jingjiao Guan
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50562F, Paper
We report development of a low-cost method to generate a centimetre-scale periodic array of single plasmid DNA of 11 kilobase pairs. The arrayed DNA is amenable to enzymatic and physical...
 
Ye Wang, Yang Gao, Hans M. Wyss, Patrick Anderson and Jaap den Toonder
Lab Chip, 2013, Accepted Manuscript
DOI: 10.1039/C3LC50458A, Paper
Micro-sized hair-like structures, such as cilia, are abundant in nature and have various functionalities. Many efforts have been made to mimic the fluid pumping function of cilia, but most of...
 
Kelly S. Burke, Dzmitry Parul, Michael J. Reddish and R. Brian Dyer
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50497B, Paper
We present a simple, yet flexible microfluidic mixer with a demonstrated mixing time as short as 80 μs that is widely accessible because it is made of commercially available parts.
 
Martina Viefhues, Sonja Wegener, Anja Rischmüller, Martin Schleef and Dario Anselmetti
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50475A, Paper
Dielectrophoresis at two nanoslits is exploited for the in-production continuous-flow quality control of gene vaccines.
 
Blanca del Rosal, Chen Sun, Despina Nelie Loufakis, Chang Lu and Daniel Jaque
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50382H, Paper
Fluorescence thermal imaging has been used to evaluate thermal loading effects in flow-through electroporation microfluidic devices.
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50413A, Paper
A two-stage hydrodynamic focusing channel shapes and sizes complex polymer fibers.
 
Narendra Kurra and Giridhar U. Kulkarni
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50406A, Focus
A pencil-trace on paper is a simple way of defining conducting tracks which have potential in making inexpensive paper based electronic devices.
 
Arnab Kundu, Liesbeth Micholt, Sarah Friedrich, Danielle R. Rand, Carmen Bartic, Dries Braeken and Andre Levchenko
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50174D, Paper
Using a novel microfabricated analysis platform, we investigate the response of primary mouse embryonic hippocampal neurons to superimposed topographic and soluble chemical cues.
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50275A, Technical Innovation
We present a novel antenna reconfiguration mechanism relying on electrowetting based digital microfluidics to implement a frequency reconfigurable antenna.
 
Hao-Ting Huang, Tzong-Rong Ger, Ya-Hui Lin and Zung-Hang Wei
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50457C, Paper
A magnetic zigzag nanowire device was designed for single cell biosensing.
 
Xu Zhang, Qian Wang, Brian Gablaski, Xiaojin Zhang, Pamela Lucchesi and Yi Zhao
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50414J, Paper
Intercellular electromechanical transduction in adult cardiac myocytes plays an important role in regulating heart function.
 
Lab Chip, 2013, Advance Article
DOI: 10.1039/C3LC50343G, Paper
Using circular travelling electroosmosis, a particle-separation microfluidic device with low-volume and low-voltage can be implemented.
 

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