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Journal cover: Lab on a Chip

Lab on a Chip

Miniaturisation for chemistry, physics, biology, materials science and bioengineering
Impact Factor 6.115 24 Issues per Year Indexed in Medline
 
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Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00265J, Technical Innovation
Many modern analytical assays, for example droplet digital PCR, or screening of the properties of single cells or single mutated genes, require splitting a liquid sample into a number of...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00307A, Paper
Electrochemical sensors are powerful analytical tools which possess the capacity for rapid detection of biomarkers in clinical specimens. While most electrochemical sensors are fabricated on rigid substrates, there is a...
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00355A, Critical Review
Dielectrophoresis is a powerful technique used to distinguish distinct cellular identities in heterogeneous cell populations, monitor changes in the cell state without the need for biochemical tags including live and...
 
Gabriel Gruionu, Despina Bazou, Nir Maimon, Mara Onita-Lenco, Lucian G. Gruionu, Peigen Huang and Lance L. Munn
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00237D, Paper
From themed collection Lab on a Chip Recent HOT Articles
Implantable tissue isolation chambers allow analyses of host–tumor interactions in vivo.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00292G, Paper
From themed collection 3D Printing
Rapid prototyping of a meter-mix device to accurately meter, lyse, and transfer urine samples for LRS and POC diagnostics.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C5LC01556A, Critical Review
From themed collection Lab on a Chip: Recent Review Articles
The synergy of novel super-resolution imaging techniques and microfluidic technology provides new biological and biomedical insights into sub-cellular processes.
 
Andy Kah Ping Tay, Felix E. Schweizer and Dino Di Carlo
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00349D, Critical Review
Biomechanical forces have been demonstrated to influence a plethora of neuronal functions across scales including gene expression, mechano-sensitive ion channels, neurite outgrowth and folding of the cortices in the brain....
 
Zuzana Tatarova, Jean-Paul Abbuehl, Sebastian Maerkl and Joerg Huelsken
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00236F, Paper
Functional analysis of primary tissue-specific stem cells is hampered by their rarity. Here we describe a greatly miniaturized microfluidic device for the multiplexed, quantitative analysis of the chemotactic properties of...
 
Jeonghun Nam, Yong Shin, Justin Kok Soon Tan, Bena Ying Lim, Chwee Teck Lim and Sangho Kim
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00162A, Paper
A novel microfluidic device for high-throughput particle separation using a viscoelastic fluid, which enables the rapid detection of extremely rare malaria parasites by using PCR analysis, is proposed. Our device...
 
Ayako Yamada, Maéva Vignes, Cécile Bureau, Alexandre Mamane, Bastien Venzac, Stephanie Descroix, Jean-Louis Viovy, Catherine Villard, Jean-Michel Peyrin and Laurent Malaquin
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00414H, Paper
Oriented neuronal networks with controlled connectivity are required for many applications ranging from studies of neurodegeneration to neuronal computation. To build such networks in vitro, an efficient, directed and long...
 
Iman Mirzaee, Minghao Song, Majid Charmchi and Hongwei Sun
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00040A, Paper
Capturing airborne particles from air into liquid is a critical process for the development of many sensors and analytical systems. A miniaturized airborne particle sampling device (microimpinger) has been developed...
 
Seung Jun Oh, Byung Hyun Park, Goro Choi, Ji Hyun Seo, Jae Hwan Jung, Jong Seob Choi, Do Hyun Kim and Tae Seok Seo
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00326E, Paper
This work describes fully automated and colorimetric foodborne pathogen detection on an integrated centrifugal microfluidic device, which is called a lab-on-a-disc.
 
Sidra Waheed, Joan-Marc Cabot Canyelles, Niall Macdonald, Rosanne Marieke Guijt, Trevor Lewis, Brett Paull and Michael C Breadmore
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00284F, Critical Review
From themed collection 3D Printing
3D printing has the potential to significantly change the field of microfluidics. The ability to fabricate a complete microfluidic device in a single step from a computer model has obvious...
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00173D, Critical Review
From themed collection Lab on a Chip: Recent Review Articles
The review highlights examples of the use of stimulus-responsive smart materials to design integral components in miniaturized-devices with specific focus on disease models and diagnostics.
 
Sungho Jang, Byungjin Lee, Heon-Ho Jeong, Si Hyung Jin, Sungyeon Jang, Seong Gyeong Kim, Gyoo Yeol Jung and Chang-Soo Lee
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00118A, Paper
From themed collection Open access articles from Lab on a Chip
We present a screening platform that couples a microfluidic static droplet array (SDA) and an artificial riboswitch to analyze intracellular metabolite concentration from single microbial cells.
 
Chao Zhou, Hua Zhang, Zeheng Li and Wei Wang
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00032K, Critical Review
From themed collection Lab on a Chip: Recent Review Articles
Lab-on-a-chip devices have over the recent years attracted a significant amount of attention in both academic circles and industry, due to their promise in delivering versatile functionalities with high throughput and low sample amount.
 
Andy K. S. Lau, Ho Cheung Shum, Kenneth K. Y. Wong and Kevin K. Tsia
Lab Chip, 2016, Advance Article
DOI: 10.1039/C5LC01458A, Critical Review
From themed collection Lab on a Chip Recent HOT Articles
Optical time-stretch imaging is now proven for ultrahigh-throughput optofluidic single-cell imaging, at least 10–100 times faster.
 
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00396F, Paper
From themed collection Lab on a Chip Recent HOT Articles
A compact microfludic device for perfusion culture of mammalian cells under in-situ metabolomic observation by NMR spectroscopy is presented. The chip is made from poly(methylmethacrylate) (PMMA), and uses a poly(dimethyl...
 
Aereas Aung, Jomkuan Theprungsirikul, Han Liang Lim and Shyni Varghese
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00184J, Paper
Chemotaxis-driven assembly of an endothelial barrier around tumor cells within a microfluidics device.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00229C, Paper
HacaT/U937 coculture-based in vitro microphysiological model of the human skin.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00416D, Paper
From themed collection Optofluidics
This paper introduces a novel nanofluidic crystal scheme by packing nanoparticles inside a well-designed confined space to improve the device-to-device readout consistency. The readout from different chips (n = 16) varied within 8.4% under the same conditions, which guaranteed a self-calibration-free biochemical sensing.
 
Nirveek Bhattacharjee, Arturo Urrios, Shawn Kang and Albert Folch
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00163G, Critical Review
From themed collection 3D Printing
A comprehensive exploration of the state-of-the-art and a critical outlook on the advantages, barriers and potential of 3D-printing in microfluidics.
 
Lab Chip, 2016, Advance Article
DOI: 10.1039/C6LC00293E, Paper
Light-driven 3D droplet manipulation on flexible single-sided optoelectrowetting (SCOEW) devices.
 
I. Schwarz, S. Zehnle, T. Hutzenlaub, R. Zengerle and N. Paust
Lab Chip, 2016, Advance Article
DOI: 10.1039/C5LC01525A, Paper
Advanced lumped element models for two phase flow in centrifugal microfluidics allow for fast layout of highly integrated centrifugal microfluidic Lab-on-a-Chip systems.
 
fu qiang qiang, Ze Wu, Fangxiang Xu, Xiuqing Li, cuize yao, Shiting Yu, Meng Xu, Yong Tang and Liangrong Sheng
Lab Chip, 2016, Accepted Manuscript
DOI: 10.1039/C6LC00083E, Paper
Plasmonic nanosensors may be used as tools for diagnostic testing in the field. However, quantification of plasmonic nanosensors often requires complex and bulky readout instruments. Here, we report the development...
 

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