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Journal cover: Lab on a Chip

Lab on a Chip

Devices and applications at the micro- and nanoscale
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Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01354F, Paper
Manipulation of a liquid droplet on a structured shape memory polymer surface with thermal Marangoni and morphological gradient forces.
Chengzhi Hu, Hannes Vogler, Marianne Aellen, Naveen Shamsudhin, Bumjin Jang, Jan T. Burri, Nino Läubli, Ueli Grossniklaus, Salvador Pané and Bradley J. Nelson
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC90041D, Correction
Shang Song, Charles Blaha, Willieford Moses, Jaehyun Park, Nathan Wright, Joey Groszek, William Fissell, Shant Vartanian, Andrew M. Posselt and Shuvo Roy
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00096K, Paper
The SNM-based iBAP demonstrates viability and functionality at clinically relevant cell density and hemocompatibility under convective transport in a porcine model.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00251C, Paper
A centrifugal microfluidic method with pre-stored reagents for automation of particle based immunoassays controlled by the spinning frequency only.
Dongha Tahk, Sang-Min Paik, Jungeun Lim, Seokyoung Bang, Soojung Oh, Hyun Ryul Ryu and Noo Li Jeon
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00363C, Paper
There are many proposed mechanisms by which single cells can be trapped, among them is the through-hole membrane for the characterization of individual microorganisms. Due to the small scale of...
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00198C, Communication
G protein-coupled receptors (GPCRs) are important targets in medical and pharmaceutical research fields, because they play key roles in a variety of biological processes. Recently, intracellular trafficking of GPCRs involving...
Fang Qian, Chao Huang, Yi-Dong Lin, Anna Ivanovskaya, Ross Booth, Tom O'hara, Cameron Creek, Heather Ann Enright, David Soscia, Anna Belle, Ronglih Liao, Felice C. Lightstone, Kristen Kulp and Elizabeth Wheeler
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00210F, Paper
Prevailing commercialized cardiac platforms for in vitro drug development utilize planar microelectrode arrays to map action potentials, or impedance sensing to record contraction in real time, but cannot record both...
Li Wang, Tingting Tao, Wentao Su, Hao Yu, Yue Yu and Jianhua Qin
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00134G, Paper
A biomimetic glomerulus-on-a-chip microdevice was created to recapitulate a disease model of diabetic nephropathy.
Qiangyuan Zhu, Yanan Xu, Lin Qiu, Congcong Ma, Bingwen Yu, Qi Song, Wei Jin, Qinhan Jin, Jinyu Liu and Ying Mu
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00267J, Paper
A scalable self-priming fractal branching microchannel net chip for digital PCR is developed for the first time.
Peter Loskill, Thiagarajan Sezhian, Kevin M. Tharp, Felipe T. Lee-Montiel, Shaheen Jeeawoody, Willie Mae Reese, Peter-James H. Zushin, Andreas Stahl and Kevin E. Healy
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01590E, Paper
Organs-on-a-chip possess a promising future as drug screening assays and testbeds for disease modeling in the context of both single-organ systems and multi-organ-chips.
Philip Hong-Sean Chao, Jeffrey Collins, Joseph P Argus, Wei-Yu Tseng, Jason T Lee and Michael van Dam
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01569G, Paper
Short-lived radiolabeled tracers for positron emission tomography (PET) must be rapidly synthesized, purified, and formulated into injectable solution just prior to imaging. Current radiosynthesizers are generally designed for clinical use,...
Javier Alejandro Hernández-Castro, Kebin Li, Anne Meunier, David Juncker and Teodor Veres
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C6LC01525E, Paper
A vacuum assisted UV micro-molding (VAUM) process is proposed for the fabrication of freestanding and defect-free polymer membranes based on UV-curable methacrylate polymer (MD 700). VAUM is a highly flexible...
Sentayehu F. Wondimu, Sebastian von der Ecken, Ralf Ahrens, Wolfgang Freude, Andreas E. Guber and Christian Koos
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01556E, Paper
WGM biosensor arrays are integrated with a DMF system. The viability of the system is demonstrated by refractive-index and biosensing experiments.
Wei Zhou, Jingjing Wang, Kaiyue Wang, Bin Huang, Lili Niu, Fei Li, Feiyan Cai, Yan Chen, Xin Liu, Xiaoyan Zhang, Hankui Cheng, Lijun Kang, Long Meng and Hairong Zheng
Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00163K, Paper
Ultrasound neuro-modulation has gained increasing attention as a non-invasive method. In this paper, we present an ultrasound-neuromoduation chip, capable of initiating reversal behaviour and activating neurons of C. elegans under...
Xuan Li, Yinglei Tao, Do-Hyun Lee, Hemantha K. Wickramasinghe and Abraham P. Lee
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00133A, Paper
mRNA probing from single cells within microfluidic arrays, combining the non-destructive and precise-control of a single-cell mRNA probe with sealed microfluidic systems' multifunctional capability.
Zachary Estlack, Devasier Bennet, Ted Reid and Jungkyu Kim
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00112F, Critical Review
Recent developments in the eye-on-a-chip platforms for ocular drug testing and possible prospective directions highlight the potential integrations.
M. Alberti, Y. Dancik, G. Sriram, B. Wu, Y. L. Teo, Z. Feng, M. Bigliardi-Qi, R. G. Wu, Z. P. Wang and P. L. Bigliardi
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01574C, Paper
We validated a novel microfluidic permeation array for high-precision and high-throughput skin penetration and toxicity testing or screening of chemicals.
David J. Collins, Bee Luan Khoo, Zhichao Ma, Andreas Winkler, Robert Weser, Hagen Schmidt, Jongyoon Han and Ye Ai
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00215G, Paper
Selective capture of biological cells using acoustic streaming vortices generated by a high-frequency, narrow-beam focused surface acoustic wave.
Shunbo Li, Johannes Ihli, William J. Marchant, Muling Zeng, Li Chen, Katia Wehbe, Gianfelice Cinque, Oscar Cespedes, Nik Kapur and Fiona C. Meldrum
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01393G, Paper
Synchrotron FTIR using a calcium fluoride microfluidic chip provides new tools for investigating mineralization process in solution in a spatial and temporal resolved manner.
Iago Pereiro, Sanae Tabnaoui, Marc Fermigier, Olivia du Roure, Stéphanie Descroix, Jean-Louis Viovy and Laurent Malaquin
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00063D, Paper
Fluidization of micromagnetic beads in microfluidics for flow-through bioanalytical operations at low driving pressures, high clogging resistance and favorable binding kinetics.
Sara Abdulwahab, Alphonsus H. C. Ng, M. Dean Chamberlain, Hend Ahmado, Lucy-Ann Behan, Hala Gomaa, Robert F. Casper and Aaron R. Wheeler
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00170C, Paper
A new regime is proposed for aromatase inhibitor therapy (AIT) in which the patient is welcomed, a core needle biopsy (CNB) sample is collected, the estradiol level in the CNB is measured, and personalized AIT is prescribed.
Marco Adamo, Andreas S. Poulos, Ruhina M. Miller, Carlos G. Lopez, Anne Martel, Lionel Porcar and João T. Cabral
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00179G, Paper
We report a microfluidic approach to perform small angle neutron scattering (SANS) measurements of contrast variation and matching, extensively employed in soft and biological matter research.
Kyuhwan Na, Mingyu Lee, Hyun-Woo Shin and Seok Chung
Lab Chip, 2017, Advance Article
DOI: 10.1039/C6LC01564F, Paper
The emergence of microfluidic epithelial models using diverse types of cells within a physiologically relevant microenvironment has the potential to be a powerful tool for preclinical drug screening and pathophysiological studies.
Rahim Rahimi, Wuyang Yu, Manuel Ochoa and Babak Ziaie
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00074J, Paper
We demonstrate a facile approach for integrating highly flexible and stretchable microfluidics into textile-based substrates by directly embroidering surface-functionalized micro-tubing.
Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00221A, Paper
Recognition-mediated high-sensitivity particle detection is a critical prerequisite to the development of effective integrated photonic virus sensors. Here, we demonstrate that 2D slab-PhC structures are able to fill this role.

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80 citations
In this paper, a review is carried out of how 3D printing helps to improve the fabrication of microfluidic devices, the 3D printing technologies currently used for fabrication and the future of 3D printing in the field of microfluidics.
DOI: 10.1039/C5LC00685F
Published: 22 Jul 2015
82 citations
We established a microfluidic four-organ-chip for interconnected long-term co-culture of human intestine (1), liver (2), skin (3) and kidney (4) equivalents.
DOI: 10.1039/C5LC00392J
Published: 13 May 2015
36 citations
3D printing has the potential to significantly change the field of microfluidics.
DOI: 10.1039/C6LC00284F
Published: 25 Apr 2016

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