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Journal cover: Analyst


The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
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Jeremy Pivetal, Filipa M. Pereira, Ana I. Barbosa, Ana P. Castanheira, Nuno M. Reis and Alexander D. Edwards
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02622B, Paper
Antibodies immobilised covalently within Teflon-FEP microcapillary devices allow sensitive fluorescent enzyme immunoassay.
O. Bibikova, J. Haas, A. I. López-Lorente, A. Popov, M. Kinnunen, I. Meglinski and B. Mizaikoff
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02596J, Paper
We report the development of plasmonic chip-based systems comprising self-assembled gold nanostars at silicon substrates that enable concomitantly enhanced Raman (surface enhanced Raman spectroscopy; SERS) and mid-infrared (surface enhanced infrared reflection or absorption spectroscopy; SEIRA) spectral signatures.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02693A, Critical Review
In this review we present the state of the art and the most recent advances in the field of optical sensing with hybrid plasmonic–photonic whispering gallery mode (WGM) resonators.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02722A, Paper
A novel colorimetric immunoassay is designed for the ultrasensitive detection of the human prostate-specific antigen (PSA) by using a unique type of nanolabel – high-index {hk0} faceted platinum concave nanocubes.
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02286C, Paper
The rise in popularity of electronic cigarettes and the associated new legislation concerning e-liquids has created a requirement for a rapid method for determining the nicotine content of e-liquids in...
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C7AN00019G, Paper
Inspired by the primitive role of lipopolysaccharide (LPS) and taking advantage of the membrane-philic property of amphiphilic gold nanoparticles (AuNPs), we established a facile and efficient fluorescence turn-on detection strategy...
Solène Cherre, Elisabete Fernandes, José Germano, Tomas Dias, Susana Cardoso, Moisés Piedade, Noemi Rozlosnik, Marta Oliveira and Paulo Peixeiro Freitas
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02651F, Paper
Microvesicles (MVs) are a promising source of diagnostic biomarkers which have gained a wide interest in the biomedical and biosensing field. They can be interpreted as a “fingerprint” of various...
James B. Sheppard, Bradley Hambly, Bradford Pendley and Erno Lindner
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02671K, Paper
The diffusion-controlled transport of ions and molecules through polymer membranes utilized in chemical and biosensors is often the key factor determining the response characteristics of these sensors. A simple voltammetric method utilizing a planar electrochemical cell allows the rapid determination of diffusion coefficients in resistive polymer membranes.
Valentina M. Farzan, Mikhail L. Markelov, Alexander Yu. Skoblov, German A. Shipulin and Timofei S. Zatsepin
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02441F, Paper
Dissection of stem and loop regions in molecular beacons by nucleotide or non-nucleotide linkers minimizes nonspecific recognition in SNP discrimination.
Rupesh K. Mishra, A. M. Vinu Mohan, Fernando Soto, Robert Chrostowski and Joseph Wang
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02625G, Paper
A microneedle array based biosensor for minimally invasive electrochemical monitoring of organophosphate (OP) nerve agents under the skin.
Jen-Kuei Wu, Peng-Chun Chen, Yu-Nan Lin, Chia-Woei Wang, Li-Chern Pan and Fan-Gang Tseng
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02420C, Paper
In this paper, we propose a microfluidic device capable of generating a retarding flow field for the sorting and separation of human motile sperm in a high-throughput manner.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02445A, Critical Review
A critical review on the development of microfluidic tests capable of the high-sensitivity measurement of protein biomarkers at the point-of-care.
Ebrahim Aboualizadeh, Mahsa Ranji, Christine M. Sorenson, Reyhaneh Sepehr, Nader Sheibani and Carol J. Hirschmugl
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02603F, Paper
A mechanistic understanding of oxidative damage in the retina and the significance of photoreceptors at the onset of diabetic retinopathy are reported.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02608G, Critical Review
Nanomaterials are, in analytical science, used for a broad range of purposes, covering the area of sample pretreatment as well as separation, detection and identification of target molecules.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02744J, Critical Review
This review provides a general overview of the recent trends for the preparation of nanocomposites and their applications in microextraction techniques.
Meltem Elitaş, Meral Yüce and Hikmet Budak
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02643E, Minireview
The development of microfabricated devices that will provide high-throughput quantitative data and high resolution in a fast, repeatable and reproducible manner is essential for plant biology research.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02666D, Communication
Mutual chiral recognition of four stereoisomers of tadalafil and three pairs of enantiomers of proton pump inhibitors (PPIs), as well as enantiomers excess analysis are achieved on the basis of the competitive fragmentation of doubly charged trimeric NiII cluster ion.
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C7AN00083A, Paper
G-quadruplex sequences exist in eukaryotic organisms and prokaryotes, and the investigation of interactions between G-quadruplexes and small molecule ligands is important for gene therapy, biosensor fabrication, fluorescence imaging and so...
Daohong Zhang, David Broyles, Eric A. Hunt, Emre Dikici, Sylvia Daunert and Sapna K. Deo
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02452A, Paper
Viral detection presents a host of challenges for even the most sensitive analytical techniques, and the complexity of common detection platforms typically preclude portability.
Ievgen Kurylo, Mathieu Dupré, Sonia Cantel, Christine Enjalbal-Goubet, Hervé Drobecq, Sabine Szunerits, Oleg Melnyk, Rabah Boukherroub and Yannick Coffinier
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02588A, Paper
In this paper, we report an original method to immobilize a model peptide on silicon nanowires (SiNWs) via a photolinker attached to the silicon surface. The silicon nanostructures were fabricated...
J. W. Martin, M. K. Nieuwoudt, M. J. T. Vargas, O. L. C. Bodley, T. S. Yohendiran, R. N. Oosterbeek, D. E. Williams and M. Cather Simpson
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN00874G, Paper
Novel open-channel centrifugal microfluidic disc design affords measurement of high quality Raman spectra of milk for detecting adulterants at point-of-collection.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02757A, Minireview
Novelty: Recent advances in real-time and in situ monitoring of an electrode–electrolyte interface by mass spectrometry are reviewed.
Lorna Ashton, Victoria L. Brewster, Elon Correa and Royston Goodacre
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02516A, Paper
We have used Raman spectroscopy and chemometrics to determine protein modification as a result of glycosylation and iron binding.
Josh Smith, Stefan Mittermayr, Csaba Váradi and Jonathan Bones
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02715F, Critical Review
Current state of the art technologies in the field of quantitative glycomics using liquid phase separations and mass spectrometry and associated informatics strategies are reviewed.
Joey G. Sheff, Morgan Hepburn, Yaping Yu, Susan P. Lees-Miller and David C. Schriemer
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02707E, Communication
An in-source column chiller supports nanoHX-MS workflows for analyzing proteins from cellular extracts.

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40 citations
Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the area of biological sensing, labelling, imaging and therapy due to their unique physical and chemical properties, such as ultrasmall size, HOMO–LUMO transition, strong luminescence together with good photostability and biocompatibility.
DOI: 10.1039/C6AN00773B
Published: 21 Apr 2016
43 citations
The development of fluorescent and colorimetric sensing strategies for environmental mercury is described.
DOI: 10.1039/C5AN00389J
Published: 01 Jun 2015
34 citations
Aptamers are target specific ssDNA, RNA or peptide sequences generated by an in vitro selection and amplification method called SELEX (Systematic Evolution of Ligands by EXponential Enrichment), which involves repetitive cycles of binding, recovery and amplification steps.
DOI: 10.1039/C5AN00954E
Published: 09 Jun 2015

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