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Analyst

The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
Impact Factor 3.969 24 Issues per Year Indexed in MEDLINE
 
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Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00344F, Paper
Non-label detection of zeptomole quantities of nonfluorescent molecules in 101 nm space by DIC-TLM.
 
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00215F, Paper
We have examined real-time, in situ hybridization detection of target DNA (tDNA) in a buffer solution and in urine using 8 μm-thick lead magnesium niobate–lead titanate (PMN–PT) piezoelectric plate sensors (PEPSs) with improved 3-mercaptopropyltrimethoxysilane (MPS) insulation and a new multiple-parabola (>50) resonance peak position fitting algorithm.
 
Kevin S. Kerian, Alan K. Jarmusch and R. Graham Cooks
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00548A, Paper
Touch spray, a spray-based ambient in situ ionization method, uses a small probe, e.g. a teasing needle to pick up sample and the application of voltage and solvent to cause field-induced droplet emission.
 
Donghyuk Kim, Antonio R. Campos, Ashish Datt, Zhe Gao, Matthew Rycenga, Nathan D. Burrows, Nathan G. Greeneltch, Chad A. Mirkin, Catherine J. Murphy, Richard P. Van Duyne and Christy L. Haynes
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00357H, Paper
Microfluidic sensing platforms facilitate parallel, low sample volume detection using various optical signal transduction mechanisms.
 
Ewa Rozniecka, Martin Jonsson-Niedziolka, Anna Celebanska, Joanna Niedziolka-Jonsson and Marcin Opallo
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02207B, Paper
A simple microfluidic device for the sensitive and selective determination of dopamine in the presence of interfering substances is reported.
 
Ian Lyle Gunsolus, Dehong Hu, Cosmin Mihai, Samuel E Lohse, changsoo Lee, Marco D Torelli, Robert Hamers, Catherine Murphy, Galya Orr and Christy Haynes
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00574K, Paper
A method to fluorescently stain the surfaces of both gram-negative and gram-positive bacterial cells compatible with super-resolution fluorescence microscopy is presented. This method utilizes a commercially-available fluorescent probe to label...
 
David Mayerich, Thomas van Dijk, Michael Walsh, Matthew Schulmerich, paul carney and Rohit Bhargava
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C3AN01687K, Paper
Infrared spectroscopic imaging provides micron-scale spatial resolution with molecular contrast. While recent work demonstrates that sample morphology affects the recorded spectrum, considerably less attention has been focused on the effects...
 
Chia-Chen Chang, Chen-Yu Chen, Xihong Zhao, Tzu-Heng Wu, Shih-Chung Wei and Chii-Wann Lin
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00253A, Communication
The development of simple and low-cost approaches for the detection of immunoglobulin E (IgE) would provide a means for the early diagnosis and prevention of atopic diseases. However, the current...
 
Qiao Song, Angela M Bamesberger, Lingyun Yang, Haley Houtwed and Haishi Cao
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00522H, Paper
A N-aryl-1,8-naphthalimide based sensor (ES-1) bearing a trimethylsilyl ether has been synthesized by a two-step reaction for quantitative detection of fluoride (F-). ES-1 exhibited monomer/excimer emissions at 410 and 524...
 
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00479E, Paper
Analysts are always interested in finding new functional nanomaterials and devices with good properties for electrochemical sensor applications. In this paper, hyperbranched polyester nanoparticles with carboxylic acid functional groups (HBPE-CA...
 
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00471J, Paper
Hydroxyl radicals (•OH) play an important role in human diseases. Traditional detection methods are time consuming and require expensive instruments. Here, we present a simple and sensitive method for hydroxyl...
 
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00329B, Paper
A novel human papillomavirus (HPV) typing assay for cervical cancer screening and prognosis was developed on combination of restriction fragment length polymorphism (RFLP) and microchip electrophoresis (MCE) to achieve higher...
 
Karen A. Esmonde-White, Francis W. L. Esmonde-White, Michael D. Morris and Blake J. Roessler
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02175K, Paper
Sessile drop formation, also called drop deposition, has been studied as a potential medical diagnostic, but the effects of complex biofluid rheology on the final deposition pattern are not well understood.
 
Vitalijs Zubkovs, Frédéric Jamme, Slavka Kascakova, Franck Chiappini, François Le Naour and Matthieu Réfrégiers
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00203B, Communication
Single photon ultraviolet microscopy is complementary to two-photon microscopy for tissue diagnosis.
 
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00389F, Paper
A sensitive and label-free DNA detection method was developed based on cascade amplification combining exonuclease-III recycling with rolling circle amplification.
 
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00183D, Paper
This paper presents a facile and highly sensitive label free electrochemical immunosensor for detection of a breast cancer biomarker using antiHER2–Fe3O4 NP bioconjugates.
 
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00250D, Paper
This work shows that different biochemical information can be obtained from the local and global Raman spectra of a single cell.
 
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02379F, Critical Review
This review article summarizes the advances in fluorescent probes on the basis of the photoinduced electron transfer (PET) mechanism towards diverse biomacromolecule targets, as well as their applications in fluorescent imaging.
 
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02279J, Paper
A new type of parallel, label-free target detection based on the combination of chip electrophoresis and a nanoparticle optical biosensor is reported.
 
Keersten Michelle Davis, Lauren Elizabeth Gibson, Frederick Haselton and David Wright
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00338A, Paper
Lateral flow immunochromatographic rapid diagnostic tests (RDTs) are the primary form of medical diagnostic used for malaria in underdeveloped nations. Unfortunately, many of these tests do not detect asymptomatic malaria...
 
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00058G, Paper
Spatial and temporal resolution of single cell exocytosis study with multiple microelectrodes.
 
Xiaojing Wang, Qingqing Miao, Tingjie Song, Qingpan Yuan, Jinhao Gao and Gaolin Liang
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00410H, Communication
Herein, we report the development of a new fluorescence switch for sequentially and selectively sensing Cu2+ and L-Histidine (L-His) in vitro and in living cells for the first time. In...
 
Boris Duran, Ricardo F. Brocenschi, Marion France, James J Galligan and Greg M. Swain
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00506F, Paper
The electrochemical pretreatment of diamond microelectrodes was investigated for the purpose of learning how an anodic, cathodic or a combined anodic + cathodic polarization affects the charge-transfer kinetics for two...
 
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00204K, Paper
Tau–tau binding induced electrostatic and conformational changes on the surface modulating the charge transfer resistance.
 
Xiaofang Niu, Dong Xu, Yunhui Yang and Yan He
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02164E, Communication
We utilized Cu2+ induced gold nanorod shortening in the presence of Na2S2O3 and NH3 for colorimetric sensing of copper ions. Compared with conventional methods, this method has good reproducibility, fast response time and very high sensitivity to Cu2+.
 

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