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Journal cover: Analyst


The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
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Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01515H, Paper
From themed collection In memory of Craig Lunte
A novel fibre-based microfluidic methodology was developed to move and isolate charged solutes, biomolecules, and intact bacterial cells, based upon a novel multi-functional 3D printed platform.
Pavithra Pathirathna, Thushani Siriwardhane, Stephen L. Morgan, Shawn P McElmurry and Parastoo Hashemi
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01807F, Paper
From themed collection In memory of Craig Lunte
Speciation controls the chemical behavior of trace metals. Thus, there is great demand for rapid speciation analysis in a variety of fields. In this study, we describe the application of...
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02063A, Paper
Imaging with the use of Raman spectroscopy enables the characterization and distinction of live cells that were freshly isolated from murine livers.
Md. Almostasim Mahmud, Eric J.M. Blondeel, Moufeed Kaddoura and Brendan David MacDonald
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02208A, Paper
In this work we describe a fabrication method to create compact and microscale features on paper based microfluidic devices using a CO2 laser cutting/engraving machine. Using this method we are...
Kisoo Kim, Junemo Koo, Sang Joon Moon and Won Gu Lee
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01506A, Paper
In this study, we present a role of arrayed micropillar structures in cell rolling dynamics. Cell rolling on a ligand coated surface as a means of cell separation was demonstrated...
Erin A. Henslee, Ruth M. Torcal Serrano, Fatima H. Labeed, Rita I. Jabr, Christopher H. Fry, Michael P. Hughes and Kai F. Hoettges
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01596D, Paper
A rapid, low-cost and label-free method of cell analysis compares favorably to Annexin-V, MTT and trypan blue for assessment of apoptosis and IC50.
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN02254E, Paper
Electrochemical determination and quantification of gingerol species by adsorptive stripping voltammetry.
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01717G, Paper
Confocal Raman microscopy has been used to measure the depth-dependent profiles of hydrogen bound water molecule types in human SC in vivo using the Gaussian function-based deconvolution procedure of the HWN region. The hydrogen bonding state of the water profile in the SC has been determined.
Michael G. Wolfe, Qiang Zhang, Christy Hui, Katherine Radford, Parameswaran Nair and John D. Brennan
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01563H, Paper
A paper-based analytical device was developed to rapidly detect myeloperoxidase in processed sputum for diagnosis of neutrophilic bronchitis.
Pavel Damborský, Katarzyna M. Koczula, Andrea Gallotta and Jaroslav Katrlík
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01746K, Paper
We present the innovative concept of a LFA using lectins in the role of the biorecognition element for glycoprofiling of biomarkers.
Frank Timmermans, Aufried T.M. Lenferink, Henk van Wolferen and Cees Otto
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01648K, Paper
An integrated Raman microscope with scanning electron microscope was used to investigate plasmonic structures by correlative SEM – SERS analysis. The integrated Raman – SEM microscope combines high resolution electron...
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN00909C, Communication
A method to produce multiple ligated primers without PCR for a target DNA containing a single point mutation is presented. A strand displacing hairpin was introduced into the reaction, enabling...
Ryan Stables, Graeme Clemens, Holly J. Butler, Katherine M. Ashton, Andrew Brodbelt, Timothy P. Dawson, Leanne M. Fullwood, Michael D. Jenkinson and Matthew J. Baker
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01583B, Paper
Spectroscopic diagnostics have been shown to be an effective tool for the analysis and discrimination of disease states from human tissue.
Yongkang Yue, Fangjun Huo, Songyi Lee, Caixia Yin and Juyoung Yoon
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01942K, Tutorial Review
Intracellular pH values are some of the most important factors that govern biological processes and the acid–base homeostasis in cells, body fluids and organs sustains the normal operations of the body.
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01086E, Paper
Large samples of semi-crystalline polymer can be rapidly visualized by polarization sensitive discrete frequency infrared (DFIR) spectroscopic imaging using a quantum cascade laser (QCL).
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01878E, Communication
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01155A, Paper
The Development of moelcularly imprinted polymer nanoparticles (MIP-NPs), which specfically bind biomolecules, is of great interest in the area of biosensors, sample purification, therapeutic agents and biotechnology. Polymerisation techniques such...
Longjiang Ding, Minggang Zhao, Sisi Fan, Hui Li, Ye Ma, Jingjing Liang and Shougang Chen
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01856D, Paper
A novel theory of employing the potential barrier to controllably adjust the electrochemical signal is demonstrated. When the redox occurs, the operation of the sensors is largely controlled by the characteristics of the p–p junction potential barrier.
Yahui Guo, Lijun Xu, Shanni Hong, Qingqing Sun, Weirong Yao and Renjun Pei
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01958G, Minireview
Label-free biosensors (LFBs) have demonstrated great potential in cost-effective applications, and most of DNA-based LFBs are based on the principle of binding-induced structural transformation. This review collected the latest reported...
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01904H, Paper
Here we describe novel covalent conjugates of antibody–phage for the detection of multiple cancer biomarkers using real time immuno-polymerase chain reaction (immuno-PCR).
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01753C, Critical Review
Advances in liquid chromatography-mass spectrometry (LC-MS) instruments and analytical strategies have brought about great progress in targeted metabolomics analysis.
O. J. Old, G. R. Lloyd, J. Nallala, M. Isabelle, L. M. Almond, N. A. Shepherd, C. A. Kendall, A. C. Shore, H. Barr and N. Stone
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01871H, Paper
Barrett's oesophagus (BE) is a premalignant condition that can progress to oesophageal adenocarcinoma. Fourier transform infrared (FTIR) mapping can be used to identify neoplastic Barrett's with high accuracy in a clinically applicable timeframe.
Karin Ortmayr, Verena Charwat, Cornelia Kasper, Stephan Hann and Gunda Koellensperger
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01342B, Paper
Uncertainty budgeting provides error intervals for fold change values and complements significance testing in non-targeted metabolomics.
William F. Siems, Larry A. Viehland and Herbert H. Hill
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01353H, Paper
Cross sections measured by ion mobility spectrometry are corrected for collision frequency and cooling/heating-controlled momentum transfer.
R. Asri, B. O'Neill, J. C. Patel, K. A. Siletti and M. E. Rice
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN01758D, Paper
From themed collection In memory of Craig Lunte
The study of transmitter interactions in the brain requires methodology to detect stimulus-driven neurotransmitter release. This report introduces an enzyme-coated 7 μm carbon-fiber microelectrode used with fast-scan cyclic voltammetry to detect evoked acetylcholine release in mouse brain slices.

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61 citations
This paper presents a critical review of recent research progress in plasmonic sensors, plasmon-enhanced fluorescence sensors, and surface-enhanced Raman scattering sensors. It places emphasis on the sensor design strategies, and highlights the applications of sensors in healthcare, homeland security, food safety and environmental monitoring.
DOI: 10.1039/C4AN01079E
Published: 06 Oct 2014
22 citations
Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the area of biological sensing, labelling, imaging and therapy due to their unique physical and chemical properties, such as ultrasmall size, HOMO–LUMO transition, strong luminescence together with good photostability and biocompatibility.
DOI: 10.1039/C6AN00773B
Published: 21 Apr 2016
28 citations
The development of fluorescent and colorimetric sensing strategies for environmental mercury is described.
DOI: 10.1039/C5AN00389J
Published: 01 Jun 2015

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