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The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
Impact Factor 3.906 24 Issues per Year Indexed in MEDLINE
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Haseong Kim, Hyo Sang Kim, Jae-Seok Ha and Seung-Goo Lee
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN02195A, Paper
The fluorescence resonance energy transfer (FRET) is widely used as core process in biometric sensors to detect small molecules such as sugars, calcium ions, or amino acids. However, FRET based...
Lorena Diéguez, Marnie Alyce Winter, Kyall John Pocock, Kristen E Bremmell and Benjamin Thierry
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN01768D, Paper
Efficient isolation strategies not based on epithelial biomarker expression are required to enable non-biased enrichment of circulating tumor cells (CTCs). CTCs undergoing epithelial-mesenchymal transition (EMT) may be prognostically relevant, and...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN02136C, Paper
We suggest a new and general model to describe the effects of temperature (T) and pH on the catalytic activity of enzymes. Despite the abundance of models to describe those...
Kyung Ho Cho, Mohd Husri, Anowarul Amin, Kamil Gotfryd, Ho Jin Lee, Juyeon Go, Jin Woong Kim, Claus J. Loland, Lan Guan, Bernadette Byrne and Pil Seok Chae
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00240K, Paper
The hydrophobic variants of the original MNG (MNG-3-C10) were evaluated with a few membrane proteins. The optimal MNG was variable for different membrane proteins, indicative of importance of match/mismatch between detergent hydrophobicity and membrane protein propensity to aggregate and denature.
Nivedita Natarajan, Padma Ramakrishnan, Vairavan Lakshmanan, Dasaradhi Palakodeti and Kannan Rangiah
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02037E, Paper
Methods were developed for the absolute quantification of metabolites from intact, regenerating planaria and from the day 3 blastema.
Chao Liang, Defang Li, Guangxian Zhang, Hui Li, Ningsheng Shao, Zicai Liang, Lingqiang Zhang, Aiping Lu and Ge Zhang
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00244C, Paper
Size separation derived from unequal primers with chemical modification (right) achieved an almost equivalent recovery rate when compared to magnetic separation (left).
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00178A, Critical Review
This review provides an update on coherent Raman scattering microscopy of cells and tissues since 2008 including CARS and SRS.
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02366H, Paper
We present a new NIR fluorescent probe for the biosynthetic pathways of H2Sn in living cells and in vivo.
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00250H, Paper
This works reports detection of electric field and hydrodynamic stress induced deformation of sub-100 nm liposomes during translocation through solid-state nanopore.
DaBin Yim, Homan Kang, Su-Ji Jeon, Hye-In Kim, Jin-Kyoung Yang, Tae Wook Kang, Sangyeop Lee, Jaebum Choo, Yoon-Sik Lee, Jin Woong Kim and Jong-Ho Kim
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02382J, Paper
A SERRS nanoprobe, GONS, is able to produce a SERRS signal strong enough to be detected at a single particle level.
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00426H, Paper
The study reported herein focused on the development and optimization of a versatile analytical methodology for characterization of intracellular distribution of protein-bound species of ruthenium originating from an anticancer Ru-based...
Liangyuan Cai, Ji Nie, Yi-Wei Zhang, Fangting Zhang, Yinglin Zhou and Xinxiang ZHANG
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00281H, Communication
Taking advantage of intrinsic characteristic of G-triplet-containing sequence, a pioneering tailor-made clip-like reporter containing three-fourths of a G-quadruplex is established. The reporter can clip the G triplet in the target...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00251F, Paper
We developed a novel protein-based bioassay platform utilizing metal-enhanced fluorescence (MEF), which is a hydrogel microarray entrapping silica-coated silver nanoparticles (Ag@SiO2). As a model system, different concentrations of glucose were...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00230C, Paper
Low-level cadmium ion (Cd2+) exposure contributes much toward the causation of chronic disease. Due to its low permissible exposure limit, overexposures may occur even in situations where trace quantities of...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00221D, Paper
Fully understanding and easy construction of specific biosensing principle is necessary for disease diagnostics and therapeutics in the hope to create new types of biosensors. Herein, we developed a new...
Sabine Schulz, Sebastian Wagner, Stefanie Gerbig, Herbert Waechter, Detlef Sielaff, Dieter Bohn and Bernhard Spengler
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00338E, Paper
Phthalates are used as plasticizes in many everyday items, but some of them are known as hormone disruptors, being especially harmful during childhood. The European Union therefore restricted their application...
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02139H, Paper
Simultaneous imaging of the topography and electrochemical activity using a dual functional L-shaped nanoprobe.
Leilei Xu, Jiajia Chen, Jun Gao, Hongxiu Yu and Pengyuan Yang
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02355B, Paper
Homocysteinylation on histone H3 was first identified by LC-MS/MS, which affects methylation and acetylation levels of histone H3.
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN01507J, Paper
Liver cancer is the fifth most common cancer in men and seventh most common cancer in women worldwide. Intoxicant induced liver injury is one of the major causes for severe...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00235D, Paper
The structural characterization of proteins using electrospray ionization mass spectrometry (ESI-MS) has become an important method for understanding protein structural dynamics. The correlation between the structures of proteins in solution...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN02400A, Paper
Water-soluble fluorescent silver nanoclusters (NCs) formed on biomolecule ligands have been extensively studied due to their great potential as new biocompatible fluorescent materials for biosensors. As synthetic ligands, proteins in...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00196J, Paper
Gas-diffusion microextraction (GDME) was applied in the extraction of vicinal diketones in bread samples aiming the determination of these compounds by high-performance liquid chromatography with UV-Vis detection (HPLC-UV). For the...
K. Don D. Gunaratne, Venkateshkumar Prabhakaran, Yehia M. Ibrahim, Randolph V. Norheim, Grant E. Johnson and Julia Laskin
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00220F, Communication
A high-flux electrospray source enables deposition of micrograms of mass-selected ions for studies in catalysis and materials science.
Holly J. Butler, Simon W. Fogarty, Jemma G. Kerns, Pierre L. Martin-Hirsch, Nigel J. Fullwood and Francis L. Martin
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01899K, Paper
From themed collection Optical Diagnosis
“Large” nanoparticles potentially are a good starting point in order to derive informative NIR/IR SERS analysis of biological samples.
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN02297A, Critical Review
From themed collection Analytical Sciences in the UK
Nanomaterials are revolutionising analytical applications with low-cost tests that enable detecting a target molecule in a few steps and with the naked eye.

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