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Journal cover: Analyst


The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
Impact Factor 4.107 24 Issues per Year Indexed in Medline
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Meijuan Liang, Yonglei Chen, Haijuan Zhang, Xiaoying Niu, Laifang Xu, Cuiling Ren and Xingguo Chen
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01378J, Paper
A novel and effective ratiometric fluorescence strategy was developed for rapidly, sensitively and selectively probing sulfide anions (S2−).
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00688K, Paper
As a type of secreted membrane vesicle, exosomes are an emerging mode of cell-to-cell communication. Yet as exosome samples are commonly contaminated with other extracellular vesicles, the biological roles of...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01294E, Paper
Herein we report on a rapid and highly sensitive scheme to detect trichloroethylene (TCE), an environmental contaminant, by surface enhanced Raman scattering (SERS) with multifunctional Au/TiO2 core-shell nanocomposites as SERS...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C4AN02124J, Paper
Authentic standards of known concentrations serve as authentic references for absolute quantification of plant metabolites using liquid chromatography/mass spectrometry (LC/MS). However, often such standards are not commercially available or not...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01079A, Paper
Mass spectrometry imaging (MSI) provides high spatial resolution information that is unprecedented in traditional metabolomics analyses; however, the molecular coverage is often limited to a handful of compounds and is...
Tatsuya Yoshimi, Shinichiro Kawabata, Shu Taira, Alato Okuno, Ryuta Mikawa, Shigeo Murayama, Koichi Tanaka and Osamu Takikawa
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01381J, Paper
A novel screening system, using affinity imaging mass spectrometry (AIMS), has been developed to identify protein aggregates or organ structures in unfixed human tissue. Frozen tissue sections are positioned on...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01095K, Paper
From themed collection Ion Mobility Mass Spectrometry
The direct determination of the overall topology and inter-subunit contacts of protein complexes plays an integral role in understanding how different subunits assemble into biologically relevant multisubunit complexes. Mass spectrometry...
Julie Docherty, Samuel Mabbott, W. Ewen Smith, John Reglinski, Karen Faulds, Christine Davidson and Duncan Graham
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01525A, Paper
SERS of bipyridyl complexes for the discrimination of six different metal ions.
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00838G, Paper
From themed collection Ion Mobility Mass Spectrometry
Separation and identification of isomeric species is a major challenge in lipidomics. Herein, we demonstrate that lipid isomers that differ only in position of the acyl chain, position of the double bond or double bond geometry can be distinguished using drift-tube ion mobility-mass spectrometry, even in complex biological samples.
Kevin C. Hewitt, Javad Ghassemi Rad, Hanna C. McGregor, Erin Brouwers, Heidi Sapp, Michael A. Short, Samia B. Fashir, Haishan Zeng and Ian P. Alwayn
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01080B, Paper
A high throughput Raman fiber probe system provides accurate and rapid biochemical assessment of the hepatic fat content of livers.
Qing Zheng, Hao Wu, Zongxu Shen, Wenyu Gao, Yu Yu, Yuehui Ma, Weijun Guang, Quangui Guo, Rui Yan, Junzhong Wang and Kejian Ding
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01088H, Paper
In the platform constructed by a polyaniline/graphene composite, double-stranded DNA, resulting from hybridization of a DNA probe, was escaping from or remaining on the sensor surface.
Deok-Hoon Kong, Se-Hui Jung, Hye-Yoon Jeon, Woo-Jin Kim, Young-Myeong Kim and Kwon-Soo Ha
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01151E, Paper
Protein kinase A (PKA) plays a crucial role in several biological processes; however, there is no assay with sufficient sensitivity and specificity to determine serological PKA (sPKA) activity.
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01288K, Minireview
This review summarizes the state of the art in taste, olfactory, and neural tissue- and cell-based biosensors.
Tomohiko Ikeuchi, Wilfred Espulgar, Eiichi Shimizu, Masato Saito, Jong-Kook Lee, Xiaoming Dou, Yoshinori Yamaguchi and Eiichi Tamiya
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01144B, Paper
Quantitative diagnosis of pharmacological chronotropic reactions on mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs) was successfully performed by utilizing derivative imaging analysis on recorded videos.
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN00840A, Paper
From themed collection Ion Mobility Mass Spectrometry
Fragmentation of melezitose by IMS-CID-IMS-MS.
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01700A, Communication
A novel concept of Brillouin Imaging and Sensing via Time-Resolved Optical (BISTRO) Measurements is introduced for flow cytometry applications. The system affords robust, maintenance-free and high-speed elasticity-sensitive measurements.
Long Pang, Shaofei Shen, Chao Ma, Tongtong Ma, Rui Zhang, Chang Tian, Lei Zhao, Wenming Liu and Jinyi Wang
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00799B, Paper
Cell sorting by filtration technique offers a label-free approach for cell separation on the basis of size and deformability. However, the filtration is always limited by the unpredictable variation of...
liansheng ling, Zhiyou Xiao, Houya Zhu, Aiping Xin and Yubin Li
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01371B, Paper
The formation of intramolecular triplex DNA can be regualated by Ag+ and Cys (cysteine), which switch off / on the fluorescence of Oligonucleotides, 5’-TAMRA- TTC TCT TCC TCT TCC TTC...
Martin Pengton Seah, Steve Spencer, Rasmus Havelund, Ian Gilmore and Alex G Shard
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01473E, Paper
An analysis is presented of the effect of experimental parameters such as energy, angle and cluster size on the depth resolution in depth profiling organic materials using Ar gas cluster...
Satoshi Arai, Ferdinandus, Shinji Takeoka, Shin'ichi Ishiwata, Hirotaka Sato and Madoka Suzuki
Analyst, 2015, Advance Article
DOI: 10.1039/C5AN01287B, Paper
Temperature mapping inside a fruit fly larva that was orally dosed with fluorescent nanoparticle thermosensors.
Nameera F. Baig, Sage J.B. Dunham, Nydia Morales-Soto, Joshua Shrout, Jonathan Sweedler and Paul W Bohn
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01149C, Paper
Abstract Two label-free molecular imaging techniques, Confocal Raman microscopy (CRM) and secondary ion mass spectrometry (SIMS), are combined for in situ characterization of the spatiotemporal distributions of quinolone metabolites and...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN00845J, Paper
From themed collection Ion Mobility Mass Spectrometry
Differential ion mobility spectrometry (DIMS) separations are described using similar terminology to liquid chromatography, capillary electrophoresis, and drift tube ion mobility spectrometry. The characterization and comparison of all these separations...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01402F, Paper
In this contribution, multicommutated flow analysis (MCFA) system for immunoprecipitation assays is presented. The developed bioanalytical system constructed of microsolenoid devices coupled with optoelectronic flow-through nephelometric detector is sufficient to...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01251A, Paper
Besides a crucial parameter for surgery and clinical diagnosis, hematocrit tends to affect the analytical result of point-of-care analytical devices. Therefore, an accurate and quick method for measuring hematocrit was...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01075F, Paper
Aptamers are short single-stranded oligonucleotides that fold into unique three-dimensional structures, facilitating selective and high affinity binding to their cognate targets. It is not well understood how aptamer-target interactions affect...

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