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The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
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Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02112C, Tutorial Review
Protein-stabilized gold nanoclusters (protein-Au NCs) have been an attractive frontier of nanoparticle research. Due to their unique fluorescence properties, high stability, environmentally friendly synthetic routes and nontoxicity, protein-Au NCs could...
Ying Zhou, kondapa naidu bobba, Xue Wei Lv, Dan Yang, Nithya Velusamy, Jun Feng Zhang and Sankarprasad Bhuniya
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02107G, Paper
We developed nitroreductase responsive theranostic probe 1; it comprises biotinylated rhodol in conjunction with p-nitrobenzyl functionality. The probe 1 showed remarkable fluorescence ‘turn-on’ signal in the presence of nitroreductase under...
Analyst, 2016, Advance Article
DOI: 10.1039/C6AN02119K, Communication
We present a new approach which enables lysis, extraction, and detection of inactivated Listeria monocytogenes cells from blood using isotachophoresis and recombinase polymerase amplification.
Jakub Maciej Surmacki, Laura Ansel-Bollepalli, Francesca Pischiutta, Elisa R. Zanier, Ari Ercole and Sarah Elizabeth Bohndiek
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02238C, Paper
Acute tissue biochemical response to traumatic brain injury is revealed using Raman spectroscopy.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02244H, Critical Review
This review highlights developments of FT-IR spectroscopy and imaging for applications of forensic science including fingerprints, counterfeit drugs and explosives.
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02269C, Paper
Herein, we proposed an enzyme-free strategy for amplified detection of DNA by combining the efficient fluorescence enhancement capability of β-cyclodextrin-tethered cationic polymer (cationic polyβ-CD) to pyrene with amplification capability of...
Ashley M. Smith, Kathryn A. Johnston, Scott E. Crawford, Lauren E. Marbella and Jill E. Millstone
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02206E, Critical Review
This review highlights current analytical methods for quantifying nanoparticle surface ligands and fundamental barriers to the accuracy of these techniques.
Ashley E. Ross, Maura C. Belanger, Jacob F. Woodroof and Rebecca R. Pompano
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02042A, Paper
We present the first microfluidic platform for local stimulation of lymph node tissue slices and demonstrate targeted delivery of a model therapeutic.
J. Tasseva, A. Taschin, P. Bartolini, J. Striova, R. Fontana and R. Torre
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02113A, Communication
Dry and wet drawing materials were investigated by THz time-domain spectroscopy in transmission mode.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN01699E, Communication
Nanoslits with a depth of ∼10 nm were manufactured on a germanium internal reflection element for attenuated internal reflection infrared spectroscopy.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN01939K, Tutorial Review
Microfluidic cell isolation and its applications in the biomedical field have been reviewed.
Michael J Pilling, Alex Henderson, Jonathan Shanks, Mick D Brown, Noel William Clarke and Peter Gardner
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02224C, Paper
Infrared spectral histopathology has shown great promise as an important diagnostic tool, with the potential to compliment current pathological methods. While promising, clinical translation has been hindered by the impracticalites...
Johannes Walter, Gary E. Gorbet, Tugce Akdas, Doris Segets, Borries Demeler and Wolfgang Peukert
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02236G, Paper
Accurate knowledge of size, density and composition of nanoparticles (NPs) is of major importance for their applications. In this work the hydrodynamic characterization of polydisperse core-shell NPs by means of...
Miguela Edith Sebastian Martin, David Perez-Guaita, Dean Andrew, Jack S. Richards, Bayden Robert Wood and Philip Heraud
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02075E, Paper
Attenuated Total Reflectance Infrared Spectroscopy (ATR-FTIR) has the potential to become a new diagnostic tool for malaria and other diseases. For point-of-care testing, the use of ATR-FTIR in malaria diagnosis...
Artur Dawid Surowka, Michael J Pilling, Alex Henderson, Herve Boutin, Lindan Christie, Magdalena Szczerbowska-Boruchowska and Peter Gardner
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01797E, Paper
Alzheimer's disease is one of the major causes of dementia in the elderly. The disease is caused by the misfolding of water soluble alpha-helical proteins, which leads to the accumulation...
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01896C, Paper
Broadband absorption spectroscopy integrated with microfluidics is widely used to measure the pH of samples available in small volumes. Single pass absorption spectroscopy, however, suffers from poor minimum detectable absorption...
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02006B, Paper
Dynamic alteration in the levels of cellular hydrogen peroxide (H2O2) is closely related to a variety of human diseases, as well as signal transduction pathways that regulate cell survive and...
Joëlle De Meutter, Julie Vandenameele, André Matagne and Erik Goormaghtigh
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02048H, Paper
We propose in this paper that protein microarrays could be analysed by infrared imaging in place of enzymatic or fluorescent labelling. This label-free method reports simultaneously a large series of...
Guonan Chen, Yanxia Li, Yiting Chen, Lu Huang and Benyong Lou
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02121B, Paper
A kind of protein imprinting over magnetic Fe3O4@Au multifunctional nano particles (NPs) with multiple binding sites was synthesized and investigated. Magnetic Fe3O4@Au NPs as the carrier materials were modified with...
Alexis C. Crawford, Lars Bjorn Laurentius, Timothy S. Mulvihill, Jennifer H Granger, John S. Spencer, Delphi Chatterjee, Kimberly E. Hanson and Marc Porter
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02110G, Paper
The ability to detect tuberculosis (TB) continues to be a global health care priority. This paper describes the development and preliminary assessment of the clinical accuracy of a heterogeneous immunoassay...
Lars Bjorn Laurentius, Alexis C. Crawford, Timothy S. Mulvihill, Jennifer H Granger, Ryan Robinson, John S. Spencer, Delphi Chatterjee, Kimberly E. Hanson and Marc Porter
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02109C, Paper
Patient care and prevention of disease outbreaks rely heavily on the performance of diagnostic tests. These tests are typically carried out in serum, urine, and other complex sample matrices, but...
Youlong Ma, Xiaoguang Dai, Tao Hong, Gary Munk and Matthew R. Libera
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02192A, Paper
Despite their many advantages and successes, molecular beacon (MB) hybridization probes have not been extensively used in microarray formats because of the complicating probe-substrate interactions that increase the background intensity....
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01919F, Paper
Upconversion nanoparticle (UCNP) has received increasing attention due to its unique optical properties. Recognizing that UCNPs are lanthanide-doped nanoparticles, we incorporated UCNPs into an immunoassay with inductively coupled plasma mass...
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN02135B, Paper
Breast cancer is a major public health issue among women in the world. Meanwhile new anticancer treatments struggle more and more to be accepted on the pharmaceutical market and research...
Analyst, 2016, Accepted Manuscript
DOI: 10.1039/C6AN01572G, Paper
Metered dose inhalers (MDI) and multidose powder inhalers (MPDI) are commonly used for the treatment of chronic obstructive pulmonary diseases and asthma. Currently, analytical tools to monitor particle/particle and particle/surface...

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64 citations
This paper presents a critical review of recent research progress in plasmonic sensors, plasmon-enhanced fluorescence sensors, and surface-enhanced Raman scattering sensors. It places emphasis on the sensor design strategies, and highlights the applications of sensors in healthcare, homeland security, food safety and environmental monitoring.
DOI: 10.1039/C4AN01079E
Published: 06 Oct 2014
28 citations
Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the area of biological sensing, labelling, imaging and therapy due to their unique physical and chemical properties, such as ultrasmall size, HOMO–LUMO transition, strong luminescence together with good photostability and biocompatibility.
DOI: 10.1039/C6AN00773B
Published: 21 Apr 2016
33 citations
The development of fluorescent and colorimetric sensing strategies for environmental mercury is described.
DOI: 10.1039/C5AN00389J
Published: 01 Jun 2015

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