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The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
Impact Factor 4.107 24 Issues per Year Indexed in Medline
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Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01619C, Paper
A proposed 3D HFNE was used to generate a wrapped electrospray to achieve the inhibition of sample ion expansion, thus restraining injection loss in electrospray ionization.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01864A, Paper
Aβ samples incubated alone or with modulators were serially flowed over the two channels preimmobilized with A11 and OC antibodies, and the SPR signals reflecting the distribution of the oligomers and fibrils were determined.
Xiuyun Wang, Min Xi, Mengmeng Guo, Fangmeng Sheng, Guang Xiao, Shuo Wu, Shunichi Uchiyama and Hiroaki Matsuura
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02098K, Paper
A simple strategy based on the easy modification of GCE by pre-electrolyzing it in ammonium carbamate aqueous solution was employed for the simultaneous determination of HQ and CC.
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01642H, Paper
Ischemia stroke turn out when blood flow to brain is stopped and is a major cause of death and long term disability across the globe. Excessive release of neurotransmitters is...
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01743B, Communication
Here, we demonstrate that by using a training set approach principal components analysis (PCA) can be performed on large 3D ToF-SIMS images of neuronal cell cultures.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02255J, Communication
We report a highly sensitive strategy for UDG activity detection by combining HCR amplification and a GO-based fluorescence quenching platform.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02206A, Communication
A new platform of ion-selective optodes is presented here to detect cations under thermodynamic equilibrium via ratiometric analysis.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02053K, Paper
The common drawbacks of most traditional electrochemiluminescence (ECL) immunoassays are the strict storage conditions for the ECL electrode and the steric hindrance caused by bovine serum albumin and antigen.
Xia Fu, Hongting Xiao, Shuang Liang, James J. Bao, Tianxiang Li and Yong Zhang
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01680K, Paper
A velocity gap mode of capillary electrophoresis (VGCE) method is proposed for the fractionation of mixed proteins which shows great potential to couple with MS for the top-down analysis of complex mixtures.
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01996F, Paper
The chromatographic system which is independent of organic solvents is a very important analytical method from green chemistry point of view. Temperature-responsive chromatography utilizing functional polymer based on poly (N-isopropylacrylamide)...
Kuang-Li Lee, Meng-Lin You, Cheng-Lin Tsai, Chia-Yu Hung, Shu-Yi Hsieh and Pei-Kuen Wei
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN02063H, Paper
This is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01959A, Tutorial Review
RNA binding proteins (RBP) regulate the editing, localization, stabilization, translation, and degradation of ribonucleic acids (RNA) through their interactions with specific cis-acting elements within target RNAs.
Jakub Chudziak, Deborah J. Burt, Sumitra Mohan, Dominic G. Rothwell, Bárbara Mesquita, Jenny Antonello, Suzanne Dalby, Mahmood Ayub, Lynsey Priest, Louise Carter, Matthew G. Krebs, Fiona Blackhall, Caroline Dive and Ged Brady
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02156A, Paper
Evaluation of a novel microfluidic device for epitope-independent enrichment of circulating tumour cells using clinical samples from patients with SCLC.
Eric Waidely, Abdul-Rahman Obaid Al-Yuobi, A. S. Bashammakh, Mohammad S. El-Shahawi and Roger M. Leblanc
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01884F, Critical Review
Hepatocellular carcinoma (HCC) is one of the most recurrent and lethal cancers worldwide.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01804H, Paper
Location-dependent NO/Ca2+ levels of a rat kidney are measured simultaneously using a dual amperometric/potentiometric NO/Ca2+ microsensor.
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN02159F, Paper
Serum transferrin is a key player in iron homeostasis, and its ability to deliver iron to cells via the endosomal pathway critically depends on the presence of carbonate that binds...
Huashan Wang, Juanjuan Li, Xiaoqing Zhang, Binfeng Hu, Yang Liu, Lin Zhang, Ruitao Cha, Jiashu Sun and Xingyu Jiang
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01835H, Communication
We demonstrate a microfluidics-based indirect competitive chemiluminescenceenzyme immunoassay (MIC) for multiple, sensitive, reliable and rapid detection of testosterone in human serum and urine samples. As MIC can detect biomarkers in...
E. Patel, P. Cicatiello, L. Deininger, M. R. Clench, G. Marino, P. Giardina, G. Langenburg, A. West, P. Marshall, V. Sears and S. Francese
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02016F, Paper
Blood evidence is frequently encountered at the scene of violent crimes and can provide valuable intelligence in the forensic investigation of serious offences.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01819F, Paper
Characterization of all gas-phase charge sites of natively sprayed proteins and peptides is demonstrated using 193 nm UVPD.
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN02140E, Paper
Raman optical activity (ROA) spectroscopy has been applied for the first time to study the interaction of cisplatin with DNA.
Saroj Kumar, Gloria Milani, Hideyo Takatsuki, Tobia Lana, Malin Persson, Chiara Frasson, Geertruy te Kronnie and Alf Månsson
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN02377G, Paper
Lab-on-a-chip systems with molecular motor driven transport of analytes attached to cytoskeletal filament shuttles (actin filaments, microtubules) circumvent challenges with nanoscale liquid transport. However, the filaments have limited cargo-carrying capacity...
Malcolm Burns, Gordon Wiseman, Angus Knight, P. M. Bramley, Lucy Foster, Sophie Rollinson, Andrew Paul Damant and Sandy Primrose
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01392E, Critical Review
Following a report on a significant amount of horse DNA being detected in a beef burger product on sale to the public at a supermarket in early 2013, the Elliott...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN01636C, Communication
From themed collection Ion Mobility Mass Spectrometry
We present EM∩IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the validation of structures...
Analyst, 2015, Accepted Manuscript
DOI: 10.1039/C5AN02322J, Paper
The study presents proof-of-concept for development of an impedimetric biosensor for ultrasensitive glycoprofiling of PSA. The biosensor exhibits three unique characteristics: 1) analysis of PSA with LOD down to 4...
Analyst, 2016, Advance Article
DOI: 10.1039/C5AN01840D, Paper
A rapid and inexpensive method for fetal genetic diagnosis using amniotic fluid (AF) as the starting material was demonstrated in this study.

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