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The home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences
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Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02705A, Communication
Two BODIPY-carbazole dye based fluorescent probes BCA and BCAS were designed, synthesized and encapsulated by liposomes to obtain fluorescent nanoparticles BCA-FNP and BCAS-FNP. The fluorescence imaging showed that BCA-FNP was...
Catherine Rui Jin Findlay, Jason Morrison, C. J. Mundy, Julia Sedlmair, Carol Hirschmugl and Kathleen Margaret Gough
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02056A, Paper
We present here the first demonstration of thermal source Fourier Transform Infrared (FTIR) microtomographic imaging. A prototype tomography accessory was designed with sufficient degrees of freedom to align any tilted...
Jinsong Han, Benhua Wang, Markus Bender, Kai Seehafer and Uwe H. F. Bunz
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02387H, Paper
A simple optoelectronic tongue, consisting of two charged, fluorescent poly(p-phenyleneethynylene)s at different pH-values, discriminates fruit juices after processing the quenching data by linear discriminant analysis.
V. Pirro, A. K. Jarmusch, C. M. Alfaro, E. M. Hattab, A. A. Cohen-Gadol and R. Graham Cooks
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02645A, Communication
Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection.
Ana M. Cubillas, Xin Jiang, Tijmen G. Euser, Nicola Taccardi, Bastian J. M. Etzold, Peter Wasserscheid and Philip St. J. Russell
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02144A, Paper
A single-ring hollow-core photonic crystal fibre (HC-PCF), guided by anti-resonant reflection, is investigated as a highly efficient and versatile microreactor for liquid-phase photochemistry and catalysis.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02339H, Paper
Matrix metalloproteinases (MMPs) have been considered to contribute to the progression of tumorigenesis and invasion; MMP-9 in particular, has been regarded as a priority target in cancer treatment due to its up-regulation in malignant tissues.
R. D. Arrua, A. Peristyy, P. N. Nesterenko, A. Das, D. M. D'Alessandro and E. F. Hilder
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02344D, Paper
Microparticles decorated with metal–organic frameworks exhibited a unique flow-dependent separation selectivity (FDSS) effect for the isocratic separation of small molecules.
Shangwang Le, Hui Zhou, Jinfang Nie, Chaohong Cao, Jiani Yang, Hongcheng Pan, Jianping Li and Yun Zhang
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02422J, Paper
This work reports a laser-heating-wax-printing method to fabricate paper devices for developing paper-based ELISAs that use pen-type pH meters for quantitative readout.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02239A, Paper
The first electrochemical analysis of molecular cancer biomarker hYKL-40 in blood serum samples of breast and brain tumor patients via capacitive immunosensing.
Jinhua Dong, Mototada Shichiri, Chan-I Chung, Takahiro Shibata, Koji Uchida, Yoshihisa Hagihara, Yasukazu Yoshida and Hiroshi Ueda
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02437H, Paper
Lipid peroxidation is involved in many disorders and diseases such as cardiovascular disease, cancers, neurodegenerative diseases, and even aging. Lipid peroxidation products existing in the blood or bodily fluids are...
Michael B. Hicks, Leah Salituro, Ian Mangion, Wes Schafer, Rong Xiang, Xiaoyi Gong and Christopher J. Welch
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02432G, Paper
A novel approach for the absolute quantitation of pharmaceuticals without standards using a flow-through coulometric array detector and the known electrochemical redox conversion applying Faraday's law, Q = N/Fn.
Monica Araya-Farias, Szymon Dziomba, Benjamin Carbonnier, Mohamed Guerrouache, Ichraf Ayed, Nacera Aboud, Myriam Taverna and N. Thuy Tran
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02324J, Paper
A real μTAS integrating monolith-based IMAC enrichment, electrophoresis separation and fluorescence detection of phosphopeptides is reported for the first time.
Otto Hertzberg, Alexander Bauer, Arne Küderle, Miguel A. Pleitez and Werner Mäntele
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02278B, Paper
Photothermal depth profiling is applied to total internal reflection enhanced photothermal deflection spectroscopy (TIR-PTDS) in order to study skin characteristics in vivo and to improve the sensing technique for non-invasive glucose monitoring.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN01916A, Paper
Mid-infrared microscopy has become a key technique in the field of biomedical science and spectroscopy. In this current study, we explore the use of a QCL infrared microscope to produce high definition, high throughput chemical images useful for the screening of biopsied colorectal tissue.
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02378A, Perspective
Aerosol mass spectrometry has become an indispensable technique for characterizing the chemistry of one of the world's deadliest air pollutants.
Hongmei Yang, Wenbin Yao, Yihan Wang, Lei Shi, rui Su, Debin Wan, Niusheng Xu, Wenhui Lian, Changbao Chen and Shuying Liu
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN01974A, Paper
Conventional strategies for screening of DNA triplex binders cannot be used for complicated samples such as ligand libraries created by combinatorial chemistry or from natural product extracts. In the current...
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02165D, Communication
Interest in using mesoporous materials for peptidomic research has increased recently. The present study reports a new type of matrix assisted laser desorption/ionization (MALDI) plate which is derived from electrochemically...
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02538B, Paper
In this work, highly monodispersed Cu2SnZnS4 NCs with a quasi-spherical structure are prepared to construct a sandwich-type electrochemical immunosensor for alpha fetoprotein detection. Quaternary Cu2SnZnS4 NCs as novel biomimetic catalysts...
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02584F, Paper
A 3D N-doped hierarchically porous carbon modified electrode enables simultaneous sensitive detection of ascorbic acid, dopamine and uric acid.
Yuan Zhang, xianliang Ke, Yan Liu, Zhen-Hua Zheng, Jin Meng and Han-Zhong Wang
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02479C, Communication
Herein a convenient strategy was developed to quantify protein SUMOylation. The amount of target proteins and SUMO proteins conjugated to them could be quatified through luciferase-based bioluminance detection and the...
Wei-Xian Wang, Yee-Wai Cheung, Roderick Dirkzwager, Wai-Chung Wong, Julian Alexander Tanner, Hong-Wei Li and Yuqing Wu
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02417C, Paper
Innovative nanomaterials offer significant potential for diagnosis of severe diseases of the developing world such as malaria. Small sized silver nanoclusters have shown promise for diagnostics due to their intense...
Miguel Ossandon, Joshua Balsam, Hugh a Bruck, Kostas Kalpakis and Avraham Rasooly
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02517J, Paper
Streak mode imaging flow cytometry for rare cell detection involves imaging moving fluorescently labeled cells in video mode with a CCD camera. The path of the moving cells results in...
Analyst, 2017, Accepted Manuscript
DOI: 10.1039/C6AN02599D, Paper
In this work, a simple and sensitive electrochemical aptasensor for protein (thrombin-TB used as the model) was developed by using cubic Cu2O nanocages (Cu2O-NCs) loaded with Au nanoparticles (AuNPs@Cu2O-NCs) as...
Kristin E. Burnum-Johnson, Jennifer E. Kyle, Amie J. Eisfeld, Cameron P. Casey, Kelly G. Stratton, Juan F. Gonzalez, Fabien Habyarimana, Nicholas M. Negretti, Amy C. Sims, Sadhana Chauhan, Larissa B. Thackray, Peter J. Halfmann, Kevin B. Walters, Young-Mo Kim, Erika M. Zink, Carrie D. Nicora, Karl K. Weitz, Bobbie-Jo M. Webb-Robertson, Ernesto S. Nakayasu, Brian Ahmer, Michael E. Konkel, Vladimir Motin, Ralph S. Baric, Michael S. Diamond, Yoshihiro Kawaoka, Katrina M. Waters, Richard D. Smith and Thomas O. Metz
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02486F, Communication
The continued emergence and spread of infectious agents is of great concern, and systems biology approaches to infectious disease research can advance our understanding of host–pathogen relationships and facilitate the development of new therapies and vaccines.
Elaine Spain, Kellie Adamson, Mohammad Elshahawy, Isabella Bray, Tia E. Keyes, Raymond L. Stallings and Robert J. Forster
Analyst, 2017, Advance Article
DOI: 10.1039/C6AN02609E, Paper
Novel electrochemical detection based on regioselective functionalised electrocatalytic nanoparticles suitable for the detection of low-abundance molecular biomarkers, miR-132 of neuroblastoma.

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38 citations
Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the area of biological sensing, labelling, imaging and therapy due to their unique physical and chemical properties, such as ultrasmall size, HOMO–LUMO transition, strong luminescence together with good photostability and biocompatibility.
DOI: 10.1039/C6AN00773B
Published: 21 Apr 2016
39 citations
The development of fluorescent and colorimetric sensing strategies for environmental mercury is described.
DOI: 10.1039/C5AN00389J
Published: 01 Jun 2015
33 citations
Current existing variants of ion mobility spectrometry.
DOI: 10.1039/C4AN01100G
Published: 03 Dec 2014

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