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Themed collection Emerging Investigators 2016: Novel design strategies for new functional materials

17 articles
Profile

Profile: Emerging Investigators 2016: novel design strategies for new functional materials

Journal of Materials Chemistry B profiles contributors to the Emerging Investigators issue.

Graphical abstract: Profile: Emerging Investigators 2016: novel design strategies for new functional materials
Review Article

Nano-engineered electro-responsive drug delivery systems

Nano-engineering is exploited to address the slow drug release and low drug loading of electro-responsive drug delivery systems.

Graphical abstract: Nano-engineered electro-responsive drug delivery systems
Review Article

Micro/nanostructured surfaces for self-powered and multifunctional electronic skins

We introduce recent advances in the design of bioinspired micro/nanostructures and 2D/3D structures for the enhancement of energy harvesting and multifunctional sensing properties of flexible electronic skins.

Graphical abstract: Micro/nanostructured surfaces for self-powered and multifunctional electronic skins
Communication

In vitro electrochemical characterization of polydopamine melanin as a tissue stimulating electrode material

The properties of redox active polydopamine melanin (PDM) films as a coating material for tissue stimulation electrodes were evaluated.

Graphical abstract: In vitro electrochemical characterization of polydopamine melanin as a tissue stimulating electrode material
Open Access Communication

Sensing a Bacillis anthracis biomarker with well-known OLED emitter EuTta3Phen

Dipicolinic acid (DPA) is a distinctive biomarker for bacterial spores. Here, we present the successful demonstration of dramatic Switch-OFF sensing of DPA using an easily synthesised Eu(III) phosphor applied primarily in light-emitting devices. The sensor shows excellent selectivites, and in the presence of water and phosphate is also demonstrated to be effective.

Graphical abstract: Sensing a Bacillis anthracis biomarker with well-known OLED emitter EuTta3Phen
Communication

Fluorinated smart micelles as enzyme-responsive probes for 19F-magnetic resonance

Labeling smart PEG–dendron hybrids with fluorine-containing groups transform their micelles into enzyme-responsive probes for 19F-magnetic resonance.

Graphical abstract: Fluorinated smart micelles as enzyme-responsive probes for 19F-magnetic resonance
Open Access Paper

Heparin-stabilised iron oxide for MR applications: a relaxometric study

Heparin stabilisation of Fe3O4 nanoparticles engenders exceptional stability, enhanced relaxation due to interparticle interactions, and prevention of protein-adsorption triggered thrombosis.

Graphical abstract: Heparin-stabilised iron oxide for MR applications: a relaxometric study
Open Access Paper

Evaluation of the direct effects of poly(dopamine) on the in vitro response of human osteoblastic cells

Functional poly(dopamine) coatings promise to become an efficient strategy to endow biomaterials with enhanced bioactive properties.

Graphical abstract: Evaluation of the direct effects of poly(dopamine) on the in vitro response of human osteoblastic cells
Open Access Paper

Silica core–shell particles for the dual delivery of gentamicin and rifamycin antibiotics

Increasing bacterial resistance calls for the simultaneous delivery of multiple antibiotics.

Graphical abstract: Silica core–shell particles for the dual delivery of gentamicin and rifamycin antibiotics
Open Access Paper

Controlling the ion release from mixed alkali bioactive glasses by varying modifier ionic radii and molar volume

Modifier ionic radius controls ion release from bioactive phospho-silicate glasses via silicate network compactness.

Graphical abstract: Controlling the ion release from mixed alkali bioactive glasses by varying modifier ionic radii and molar volume
Paper

Bacterial viability on chemically modified silicon nanowire arrays

Multi-functional silicon nanowires (SiNWs) arrays: (I) nanostructure topography in the form of SiNWs, (II) covalent chemical modification with APTES and (III) incorporation of chlorhexidine digluconate.

Graphical abstract: Bacterial viability on chemically modified silicon nanowire arrays
Paper

Near-infrared triggered generation of reactive oxygen species from upconverting nanoparticles decorated with an organoiridium complex

We developed an upconverting nanoparticle capable of (up)converting near-infrared excitation light to UV to sensitize an organoiridium complex for the production of reactive oxygen species.

Graphical abstract: Near-infrared triggered generation of reactive oxygen species from upconverting nanoparticles decorated with an organoiridium complex
Open Access Paper

Boronic acid-modified poly(amidoamine) dendrimers as sugar-sensing materials in water

High-affinity carbohydrate receptors were developed by appending boronic acids to the surface of PAMAM dendrimers. These multivalent hosts were used to discriminate simple sugars in neat water using pattern recognition and optical spectroscopy techniques.

Graphical abstract: Boronic acid-modified poly(amidoamine) dendrimers as sugar-sensing materials in water
Paper

Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers

We demonstrate an approach to fabricate microgels from self-assembled peptide nanofibers via desolvation. Proteins can be co-desolvated with nanofibers to create protein-loaded microgels. Modifying nanofibers with a protein-binding ligand provides tunable affinity-controlled protein release.

Graphical abstract: Microgels with tunable affinity-controlled protein release via desolvation of self-assembled peptide nanofibers
Open Access Paper

Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release

Novel amphiphilic microgels with hydrophobic and hydrophilic monomer units on the polymer chains were fabricated with an on-chip polymerisation methodology using a novel chip design.

Graphical abstract: Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release
Paper

Characterization and optimization of pH-responsive polymer nanoparticles for drug delivery to oral biofilms

Corona and core molecular weights of p(DMAEMA)-b-p(DMAEMA-co-BMA-co-PAA) block copolymer micelles can be tuned to enhance drug release in response to acidic milieus consistent with oral biofilms.

Graphical abstract: Characterization and optimization of pH-responsive polymer nanoparticles for drug delivery to oral biofilms
Open Access Paper

Glycosylated gold nanoparticle libraries for label-free multiplexed lectin biosensing

Glycosylated nanoparticle libraries are developed to enable ‘barcode’ sensing of lectins and toxins.

Graphical abstract: Glycosylated gold nanoparticle libraries for label-free multiplexed lectin biosensing
17 articles

About this collection

Journal of Materials Chemistry B is proud to present this themed issue highlighting 2016’s rising stars of materials chemistry research. This issue gathers the very best work from materials chemists in the early stages of their independent career, with a special focus on novel design strategies for new functional materials.

Each contributor was recommended by our prestigious Editorial Board as carrying out work with the potential to influence future directions in materials chemistry. Congratulations to all of those who feature on their important work so far in the field of materials for biology and medicine.

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