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Themed collection Modern Methods in Plant Natural Products

9 articles
Cover

Front cover

Graphical abstract: Front cover
From the themed collection: Modern Methods in Plant Natural Products
Editorial

Editorial: Modern Methods in Plant Natural Products themed issue

From the themed collection: Modern Methods in Plant Natural Products
Highlight

Bioinformatics challenges in de novo transcriptome assembly using short read sequences in the absence of a reference genome sequence

This Highlight article provides an overview of the bioinformatics challenges associated with transcriptome analyses using short read sequences and how to address these issues in plant species that lack a reference genome.

Graphical abstract: Bioinformatics challenges in de novo transcriptome assembly using short read sequences in the absence of a reference genome sequence
From the themed collection: Modern Methods in Plant Natural Products
Review Article

Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays

This review covers technologies which have been designed to generate pre-fractionated extract libraries and efficiently correlate biological data with chemo-analytical information.

Graphical abstract: Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays
From the themed collection: Modern Methods in Plant Natural Products
Review Article

Mass spectrometry and NMR spectroscopy: modern high-end detectors for high resolution separation techniques – state of the art in natural product HPLC-MS, HPLC-NMR, and CE-MS hyphenations

Natural product research is unthinkable without hyphenated instrumental analysis platforms as HPLC-MS, CE-MS, or HPLC-NMR. This review provides an overview of latest technological developments, discusses the assets and drawbacks of the available techniques, and describes typical analytical workflows and applications.

Graphical abstract: Mass spectrometry and NMR spectroscopy: modern high-end detectors for high resolution separation techniques – state of the art in natural product HPLC-MS, HPLC-NMR, and CE-MS hyphenations
From the themed collection: Modern Methods in Plant Natural Products
Review Article

21st Century natural product research and drug development and traditional medicines

21st century 'omics technologies linked with robust ethnobotanical and ethnomedical studies of traditional medicines can improve current treatments of malaria and TB and many chronic diseases. The Saffron Gatherers at Akrotiri-Santorini exemplifies the traditional uses of plants and natural products that also provide a foundation for new and improved medicines.

Graphical abstract: 21st Century natural product research and drug development and traditional medicines
From the themed collection: Modern Methods in Plant Natural Products
Review Article

A global approach to analysis and interpretation of metabolic data for plant natural product discovery

Discovering molecular functionality is key to development of hypotheses concerning the organization and regulation of metabolic networks. Here, we detail public metabolomics repositories, approaches for data analysis and integration with transcriptomics to explore natural product biochemistry.

Graphical abstract: A global approach to analysis and interpretation of metabolic data for plant natural product discovery
From the themed collection: Modern Methods in Plant Natural Products
Open Access Review Article

Natural product isolation – how to get from biological material to pure compounds

Methods used in the course of isolation of secondary compounds from higher plants, marine organisms and microorganisms are discussed, covering work published between 2008 and 2012.

Graphical abstract: Natural product isolation – how to get from biological material to pure compounds
From the themed collection: Modern Methods in Plant Natural Products
Review Article

Using NMR to identify and characterize natural products

The use of 2D NMR and selective 1D NMR experiments has helped to revolutionize natural product structure elucidation. This review focuses on the improvements in NMR pulse sequences and processing methods that have contributed to this revolution.

Graphical abstract: Using NMR to identify and characterize natural products
From the themed collection: Modern Methods in Plant Natural Products
9 articles

About this collection

NPR is delighted to publish a collection of reviews focussing on modern methods in plant natural products. Guest Edited by Simon Gibbons and Sarah O’Connor, this collection brings insight into how the rapid advances in analytical technique seen in recent years have revolutionised the field.

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