Jump to main content
Jump to site search

Themed collection Integrative Biology 2016 Most Downloaded Articles

10 items
Review Article

Three-dimensional models for studying development and disease: moving on from organisms to organs-on-a-chip and organoids

Organ-on-a-chip and organoid culture models present complementary approaches in studying development and disease by balancing experimental tractability and the ability to mimic physiological complexity.

Graphical abstract: Three-dimensional models for studying development and disease: moving on from organisms to organs-on-a-chip and organoids
From the themed collection: Integrative Biology Recent HOT Articles
Review Article

A morphospace for synthetic organs and organoids: the possible and the actual

Guiding synthetic organ exploration through acknowledging self-organisation and evolutionary constraints in the morphospace of the possible and the actual.

Graphical abstract: A morphospace for synthetic organs and organoids: the possible and the actual
From the themed collection: Biological Insights from Synthetic Biology
Open Access Review Article

The appeasement of Doug: a synthetic approach to enhancer biology

In this review, we discuss how we can use synthetic approaches to study animal enhancers, as well as the importance of both positive and negative results for advancing the field of developmental gene regulation.

Graphical abstract: The appeasement of Doug: a synthetic approach to enhancer biology
Open Access Review Article

Genetically modified bacteriophages

Applications of genetically modified bacteriophages.

Graphical abstract: Genetically modified bacteriophages
From the themed collection: Biological Insights from Synthetic Biology
Open Access Paper

Mechanical phenotyping of primary human skeletal stem cells in heterogeneous populations by real-time deformability cytometry

Mechanical measurements of skeletal stem cells using RT-DC reveal a distinct sub-population within the human bone marrow.

Graphical abstract: Mechanical phenotyping of primary human skeletal stem cells in heterogeneous populations by real-time deformability cytometry
Open Access Paper

Chemical communication between bacteria and cell-free gene expression systems within linear chains of emulsion droplets

Using 1D arrangements of microdroplets to exchange chemical messages between cell-free systems and bacteria.

Graphical abstract: Chemical communication between bacteria and cell-free gene expression systems within linear chains of emulsion droplets
Paper

Modeling type 2 diabetes-like hyperglycemia in C. elegans on a microdevice

A microdevice to model type 2 diabetes-like hyperglycemia in C. elegans and examine several aspects of this disease in C. elegans.

Graphical abstract: Modeling type 2 diabetes-like hyperglycemia in C. elegans on a microdevice
From the themed collection: Integrative Biology Recent HOT Articles
Open Access Paper

Mimicking the topography of the epidermal–dermal interface with elastomer substrates

Micro-scale topography mimics stem cell patterning in human interfollicular epidermal stem cells.

Graphical abstract: Mimicking the topography of the epidermal–dermal interface with elastomer substrates
From the themed collection: Integrative Biology Recent HOT Articles
Paper

Time series modeling of live-cell shape dynamics for image-based phenotypic profiling

Live-cell imaging can be used to capture spatio-temporal aspects of cellular responses that are not accessible to fixed-cell imaging.

Graphical abstract: Time series modeling of live-cell shape dynamics for image-based phenotypic profiling
Technical Innovation

Microfluidic device for simultaneous analysis of neutrophil extracellular traps and production of reactive oxygen species

Simultaneous analysis of the production of reactive oxygen species and formation of extracellular traps from neutrophils isolated from a drop of blood using a novel microfluidics based approach.

Graphical abstract: Microfluidic device for simultaneous analysis of neutrophil extracellular traps and production of reactive oxygen species
From the themed collection: Integrative Biology Recent HOT Articles
10 items

About this collection

This web collection features the top 10 most downloaded articles published in Integrative Biology in 2016. Congratulations to all of the authors whose articles have been featured!

Spotlight

Advertisements