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Themed collection Most accessed Food & Function articles in 2016

30 articles
Editorial

Dietary polysaccharides and polyphenols can promote health by influencing gut microbiota populations

Guest editors Michael Conlon and David Topping introduce this themed collection on foods, the large bowel microbiota and health outcomes.

Graphical abstract: Dietary polysaccharides and polyphenols can promote health by influencing gut microbiota populations
From the themed collection: Probiotics, Prebiotics and Gut Health
Review Article

Probiotics in early life: a preventative and treatment approach

Microbial colonization of the infant gut plays a key role in immunological and metabolic pathways impacting human health.

Graphical abstract: Probiotics in early life: a preventative and treatment approach
From the themed collection: Probiotics, Prebiotics and Gut Health
Review Article

Diet, microbiota, and dysbiosis: a ‘recipe’ for colorectal cancer

The food we consume feeds not only us, but also a vast and diverse community of microbiota within our gastrointestinal tract.

Graphical abstract: Diet, microbiota, and dysbiosis: a ‘recipe’ for colorectal cancer
From the themed collection: Recent HOT articles
Review Article

The absorption, distribution, metabolism and excretion of procyanidins

This review summarizes research on the in vivo and in vitro ADME of procyanidins (PAs), including the degradation of PAs in gastric digestion, their absorption in the small intestine and the pathway of their metabolism by colonic microflora. A systematic comparative analysis of published data is performed to elucidate the pharmacokinetics of PAs in vivo.

Graphical abstract: The absorption, distribution, metabolism and excretion of procyanidins
Open Access Review Article

Dietary protein intake and human health

A protein consists of amino acids (AA) linked by peptide bonds.

Graphical abstract: Dietary protein intake and human health
From the themed collection: Recent HOT articles
Review Article

Cardiovascular benefits of probiotics: a review of experimental and clinical studies

The microbiota inhabiting the human gastro-intestinal tract is reported to have a significant impact on the health of an individual.

Graphical abstract: Cardiovascular benefits of probiotics: a review of experimental and clinical studies
From the themed collection: Probiotics, Prebiotics and Gut Health
Review Article

Relevant pH and lipase for in vitro models of gastric digestion

Expressing gastric pH as a function of gastric emptying instead of time makes it possible to reduce the inter-individual variability and highlight the pH values that are the most relevant for testing meal digestion in the stomach.

Graphical abstract: Relevant pH and lipase for in vitro models of gastric digestion
Review Article

Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation

In 1985 carboxymethyl-lysine (CML), the first glycoxidation product, was discovered by Dr Ahmed while trying to identify the major products formed in reactions of glucose with lysine under physiological conditions.

Graphical abstract: Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation
Open Access Review Article

Edible oil structuring: an overview and recent updates

The recent updates in the field of edible oil structuring is reviewed with the help of suitable examples of structuring agents and edible applications.

Graphical abstract: Edible oil structuring: an overview and recent updates
Open Access Paper

Food-grade Pickering emulsions stabilised with solid lipid particles

Aqueous dispersions of tripalmitin particles (with a minimum size of 130 nm) were produced, via a hot sonication method, with and without the addition of food-grade emulsifiers.

Graphical abstract: Food-grade Pickering emulsions stabilised with solid lipid particles
Paper

High pressure processing of meat: effects on ultrastructure and protein digestibility

The effects of high pressure processing (HPP, at 175 and 600 MPa) on the ultrastructure and in vitro protein digestion of bovine longissimus dorsi muscle meat were studied.

Graphical abstract: High pressure processing of meat: effects on ultrastructure and protein digestibility
Open Access Paper

In vitro bioaccessibility of proteins and lipids of pH-shift processed Nannochloropsis oculata microalga

The present study demonstrates that cell disruption is necessary to make Nannochloropsis proteins and lipids accessible to mammalian digestive enzymes used in the applied in vitro digestion model.

Graphical abstract: In vitro bioaccessibility of proteins and lipids of pH-shift processed Nannochloropsis oculata microalga
Paper

Impact of increasing fruit and vegetables and flavonoid intake on the human gut microbiota

Plant-derived dietary fibre and/or flavonoids may mediate the protective effects of fruits and vegetables (F&V) in lowering the risk of developing cardiovascular diseases (CVD) and cancers particularly through their interaction with the gut microbiota.

Graphical abstract: Impact of increasing fruit and vegetables and flavonoid intake on the human gut microbiota
From the themed collection: Probiotics, Prebiotics and Gut Health
Open Access Paper

Formation of reactive aldehydes (MDA, HHE, HNE) during the digestion of cod liver oil: comparison of human and porcine in vitro digestion models

Higher levels of reactive lipid oxidation products are formed during the digestion of cod liver oil when using human compared to porcine in vitro digestion models.

Graphical abstract: Formation of reactive aldehydes (MDA, HHE, HNE) during the digestion of cod liver oil: comparison of human and porcine in vitro digestion models
Paper

Intactness of cell wall structure controls the in vitro digestion of starch in legumes

Increasing the level of starch that is not digested by the end of the small intestine and therefore enters the colon (‘resistant starch’) is a major opportunity for improving the nutritional profile of foods.

Graphical abstract: Intactness of cell wall structure controls the in vitro digestion of starch in legumes
Open Access Paper

Formation of malondialdehyde (MDA), 4-hydroxy-2-hexenal (HHE) and 4-hydroxy-2-nonenal (HNE) in fish and fish oil during dynamic gastrointestinal in vitro digestion

Reactive lipid peroxidation products (MDA, HHE and HNE) are formed during dynamic gastrointestinal in vitro digestion of fish and fish oil.

Graphical abstract: Formation of malondialdehyde (MDA), 4-hydroxy-2-hexenal (HHE) and 4-hydroxy-2-nonenal (HNE) in fish and fish oil during dynamic gastrointestinal in vitro digestion
Paper

Extrusion of barley and oat influence the fecal microbiota and SCFA profile of growing pigs

The effect of extrusion of barley and oat on the fecal microbiota and the formation of SCFA was evaluated using growing pigs as model system. The pigs were fed a diet containing either whole grain barley (BU), oat groat (OU), or their respective extruded samples (BE and OE).

Graphical abstract: Extrusion of barley and oat influence the fecal microbiota and SCFA profile of growing pigs
Open Access Paper

Pro198Leu polymorphism affects the selenium status and GPx activity in response to Brazil nut intake

Selenoproteins play important roles in antioxidant mechanisms, but it is hypothesised that single polymorphism nucleotides (SNPs) may affect their function.

Graphical abstract: Pro198Leu polymorphism affects the selenium status and GPx activity in response to Brazil nut intake
From the themed collection: Alzheimer's Research Month 2016
Paper

Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro

Mulberry fruit polysaccharide fractions with different structural characteristics showed different antioxidant and hypoglycemic activities.

Graphical abstract: Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro
Paper

Enhancement of carotenoid bioaccessibility from carrots using excipient emulsions: influence of particle size of digestible lipid droplets

The influence of initial lipid droplet size on the ability of excipient emulsions to increase carotenoid bioaccessibility from carrots was investigated using a simulated gastrointestinal tract (GIT).

Graphical abstract: Enhancement of carotenoid bioaccessibility from carrots using excipient emulsions: influence of particle size of digestible lipid droplets
Open Access Paper

Acutely administered grape-seed proanthocyanidin extract acts as a satiating agent

Grape-seed proanthocyanidins could be useful as a satiating agent under defined conditions.

Graphical abstract: Acutely administered grape-seed proanthocyanidin extract acts as a satiating agent
Open Access Paper

Glycemic index and microstructure analysis of a newly developed fiber enriched cookie

A diet with a high glycemic index (GI) is associated with an elevated risk for obesity or type 2 diabetes.

Graphical abstract: Glycemic index and microstructure analysis of a newly developed fiber enriched cookie
Open Access Paper

The role of plant cell wall encapsulation and porosity in regulating lipolysis during the digestion of almond seeds

Intact cell walls of almond prevent lipase penetration thus hindering lipid digestion.

Graphical abstract: The role of plant cell wall encapsulation and porosity in regulating lipolysis during the digestion of almond seeds
Open Access Paper

The decrease in the IgG-binding capacity of intensively dry heated whey proteins is associated with intense Maillard reaction, structural changes of the proteins and formation of RAGE-ligands

Heat treatment is the most common way of milk processing, inducing structural changes as well as chemical modifications in milk proteins.

Graphical abstract: The decrease in the IgG-binding capacity of intensively dry heated whey proteins is associated with intense Maillard reaction, structural changes of the proteins and formation of RAGE-ligands
Paper

Formulation and characterization of nanoencapsulated curcumin using sodium caseinate and its incorporation in ice cream

The preparation and characterization of a curcumin nanoemulsion with milk protein (sodium caseinate) were undertaken. The findings suggest that ice cream is a suitable dairy product for the delivery of lipophilic bioactive components which can be used for therapeutic purposes.

Graphical abstract: Formulation and characterization of nanoencapsulated curcumin using sodium caseinate and its incorporation in ice cream
Paper

In vitro starch digestibility and in vivo glycemic response of foxtail millet and its products

Foxtail millet, as a leading variety in arid and semi-arid areas of Asia and Africa, can provide broad potential benefits to human health.

Graphical abstract: In vitro starch digestibility and in vivo glycemic response of foxtail millet and its products
Paper

Food matrix and processing influence on carotenoid bioaccessibility and lipophilic antioxidant activity of fruit juice-based beverages

Food matrix and food processing are factors of importance in designing food and beverages with a high content of bioaccessible carotenoids.

Graphical abstract: Food matrix and processing influence on carotenoid bioaccessibility and lipophilic antioxidant activity of fruit juice-based beverages
Paper

Long-chain polyunsaturated fatty acids amend palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes

Long-chain PUFAs inhibit inflammation and insulin resistance in mouse C2C12 myotubes.

Graphical abstract: Long-chain polyunsaturated fatty acids amend palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes
Paper

Curcumin prevents cisplatin-induced decrease in the tight and adherens junctions: relation to oxidative stress

Curcumin decreases cisplatin-induced nephrotoxicity by decreasing oxidative stress and loss of intercellular junctions.

Graphical abstract: Curcumin prevents cisplatin-induced decrease in the tight and adherens junctions: relation to oxidative stress
Paper

Mulberry anthocyanin extract regulates glucose metabolism by promotion of glycogen synthesis and reduction of gluconeogenesis in human HepG2 cells

We suggest that a mulberry anthocyanin extract regulates glucose metabolism by activating the PI3K/AKT pathway in HepG2 cells.

Graphical abstract: Mulberry anthocyanin extract regulates glucose metabolism by promotion of glycogen synthesis and reduction of gluconeogenesis in human HepG2 cells
30 articles

About this collection

This themed collection features the top 30 most downloaded articles published in Food & Function in 2016. Congratulations to all of the authors whose articles have been featured.

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