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Themed collection Supramolecular Medicine

11 items
Editorial

Supramolecular medicine

Guest editors Honggang Cui and Bing Xu introduce the supramolecular medicine issue of Chemical Society Reviews. In a broader context, Supramolecular Medicine can be defined as the supramolecular formulation of diagnostic and therapeutic agents for the diagnosis, treatment, and prevention of disease.

Graphical abstract: Supramolecular medicine
From the themed collection: Supramolecular Medicine
Review Article

Self-assembling prodrugs

Covalent modification of therapeutic compounds is a clinically proven strategy to devise prodrugs with enhanced treatment efficacies. Self-assembly of prodrugs expands the functional space of conventional prodrug design, providing a possible pathway to more effective therapies.

Graphical abstract: Self-assembling prodrugs
From the themed collection: Supramolecular Medicine
Open Access Review Article

From supramolecular polymers to multi-component biomaterials

This review features the translation of supramolecular fibers into elastomers and hydrogels for regenerative medicine.

Graphical abstract: From supramolecular polymers to multi-component biomaterials
From the themed collection: Supramolecular Medicine
Review Article

Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application

This review highlights the recent advances in the chemical design, supramolecular assembly, and biomedical application of synthetic polypeptides from N-carboxyanhydrides.

Graphical abstract: Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application
From the themed collection: Supramolecular Medicine
Review Article

Molecular engineering solutions for therapeutic peptide delivery

This review discusses self-assembled vehicles as nanoparticles to carry and protect therapeutic peptides through their journeys in the body.

Graphical abstract: Molecular engineering solutions for therapeutic peptide delivery
From the themed collection: Supramolecular Medicine
Review Article

Drug delivery by supramolecular design

Principles rooted in supramolecular chemistry have empowered new and highly functional therapeutics and drug delivery devices. This general approach offers elegant tools rooted in molecular and materials engineered to address the many challenges faced in treating disease.

Graphical abstract: Drug delivery by supramolecular design
From the themed collection: Supramolecular Medicine
Review Article

Spatiotemporal hydrogel biomaterials for regenerative medicine

This review highlights recent efforts in using photochemistry to exert dynamic control over the properties of hydrogel biomaterials.

Graphical abstract: Spatiotemporal hydrogel biomaterials for regenerative medicine
From the themed collection: Supramolecular Medicine
Review Article

Implications of peptide assemblies in amyloid diseases

We highlight the role of molecular self-assembly in eliciting the mesoscopic and pathological properties of amyloid proteins. This knowledge is pivotal for the development of theranostics against amyloid diseases.

Graphical abstract: Implications of peptide assemblies in amyloid diseases
From the themed collection: Supramolecular Medicine
Tutorial Review

Advancing porphyrin's biomedical utility via supramolecular chemistry

Enhancing existing porphyrin functionality and introducing new capabilities via supramolecular chemistry.

Graphical abstract: Advancing porphyrin's biomedical utility via supramolecular chemistry
From the themed collection: Supramolecular Medicine
Tutorial Review

Guanidinium-based “molecular glues” for modulation of biomolecular functions

This tutorial review highlights “molecular glues” designed for manipulation of biomolecular assemblies, drug delivery systems, and modulation of biomolecular functions.

Graphical abstract: Guanidinium-based “molecular glues” for modulation of biomolecular functions
From the themed collection: Supramolecular Medicine
Tutorial Review

Supramolecular catalysis and dynamic assemblies for medicine

This review provides new insights into supramolecular catalysis and dynamic regulation of molecular assemblies for biomedical applications.

Graphical abstract: Supramolecular catalysis and dynamic assemblies for medicine
From the themed collection: Supramolecular Medicine
11 items

About this collection

We are pleased to present our Chemical Society Reviews themed issue on supramolecular medicine. Guest edited by Professor Honggang Cui (Johns Hopkins University, USA) and Professor Bing Xu (University of Pennsylvania, USA), this issue aims to provide an overview of recent developments in the expanding field of supramolecular medicine, an area focusing on the utilization of supramolecular structures to address emerging issues in healthcare. This themed issue in supramolecular medicine brings together leading experts working on supramolecular chemistry, biomaterials, molecular engineering, and pharmaceutical sciences, to review the recent progress in utilizing supramolecular nanostructures and materials to address emergent issues in health and disease, and to share their visions for future research directions in supramolecular design, non-covalent synthesis, biomaterial fabrication, and important medical applications.

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