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Themed collection Chemical signaling at the eukaryotic/prokaryotic interface

7 items
Review Article

Chemical strategies to unravel bacterial–eukaryotic signaling

This review highlights the use of advanced chemical biology methods to decipher the language of bacterial–plant and bacterial–mammalian interactions.

Graphical abstract: Chemical strategies to unravel bacterial–eukaryotic signaling
Review Article

Chemical signaling involved in plant–microbe interactions

Plant and microorganisms actively communicate through chemical entities.

Graphical abstract: Chemical signaling involved in plant–microbe interactions
Review Article

Engineering chemical interactions in microbial communities

Microbes can be engineered to participate in chemical signaling within host-associated microbial communities (microbiotas).

Graphical abstract: Engineering chemical interactions in microbial communities
Review Article

Secondary metabolism in the lichen symbiosis

Lichens, which are defined by a symbiosis between a mycobiont (fungal partner) and a photobiont (photoautotrophic partner), are in fact complex assemblages of microorganisms that constitute a largely untapped source of bioactive secondary metabolites.

Graphical abstract: Secondary metabolism in the lichen symbiosis
Review Article

Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential

We review action mechanisms and therapeutic potential of natural products that modulate human sensations and mood through specific molecular receptors.

Graphical abstract: Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential
Review Article

Defense contracts: molecular protection in insect-microbe symbioses

Insects frequently host microbes that produce defensive molecules: a successful protective strategy and also an opportunity for antibiotic discovery

Graphical abstract: Defense contracts: molecular protection in insect-microbe symbioses
Tutorial Review

An integrative omics perspective for the analysis of chemical signals in ecological interactions

All living organisms emit, detect, and respond to chemical stimuli, thus creating an almost limitless number of interactions by means of chemical signals.

Graphical abstract: An integrative omics perspective for the analysis of chemical signals in ecological interactions
7 items

About this collection

We are pleased to present our Chemical Society Reviews themed issue on Chemical signaling at the eukaryotic/prokaryotic interface, guest edited by Pieter Dorrestein (University of California, San Diego, USA) and Emily Balskus (Harvard University, USA). Organisms do not live in isolation and have co-evolved to interact. One of the main modes of interactions is through chemical signals. Such signals initiate how insects are attracted to crops, how corals are attracted to microbes to colonize and even define who we are as a human where signals from gut microbes affect our neuro-circuitry. There are many success stories but also technological advancements. The aim of this special issue is not only to describe the chemistries that have been described in the literature but also emerging advances as well as lay out a vision for the future in chemical analysis applicable to the investigations chemical signaling. In this special issue we highlight not only the state-of-the-art knowledge about signaling but also highlight the emerging advances.

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