Themed collection Recent HOT articles

Plasma-based ambient mass spectrometry (AMS) exhibits great potential in the direct analysis of raw samples with minimum pretreatment.

The risks posed by viral diseases have been recognised as critical threats to mankind.

Improved design of sampling microplastic waste is necessary. Important problems are identified and suggestions for improvements are made.

Using commercially available personal glucose meters for the determination of hexokinase activity.

A novel pyrene-based fluorescent probe (3-methyl-2-(pyren-1-yl)benzo[d]thiazol-3-ium iodide) (PBT) was found to be a fast-responsive and highly selective towards G-quadruplexes. PBT exhibited an opposite fluorescent variation tendency on binding with G-quadruplexes and ds-DNAs.

An alternative method using MBTH as a spectrophotometric probe for the determination of total phenolic compounds in samples of wines (red and white), coffees (instant and brewed), teas and infusions.

A simple dispersive solid-phase extraction method coupled with atomic absorption spectrometry detection was developed for selective separation of ultra-trace of lead ion using graphene oxide modified such as the pseudo imprinted polymer sorbent in real samples.

An all-graphene-based disposable sensor with a ‘built in’ internal reference was applied for the stripping analysis of heavy metals.

Analytical centrifugation in sedimentation and flotation modes is used to measure both the size and density of polystyrene nanoparticles.

We have designed and synthesized a polyfluorene probe with side-chain terminals functionalized with Boc-NH– units (PF6-Boc) for ultrasensitive RDX explosive vapor detection.

Salicylidene Schiff bases (SASBs) have attracted significant attention because they have unique properties and can be simply synthesized by the condensation reactions; however, their poor fluorescence in solution makes them unable to be used as a fluorescent turn-off probe and limits their application fields.

Quantitative comparison of three representative staining methods for developing multichannel colorimetric biochips, which allow visual detection of multiple cancer markers.

A simple Pt and Pd bimetal nanowire based stereoselective sensor for the recognition of ascorbic acid and isoascorbic acid.

N-Nitrosamines (NAs) are potent carcinogens and have been found in food products.

A new analytical method was developed to quantify cocaine and some adulterants using nuclear magnetic resonance spectroscopy without the use of deuterated solvents.

Despite changes in the analytical methodology and the population of participant laboratories, there was remarkably little change in the consensus values.

In this contribution, an ultra-sensitive electrochemiluminescence (ECL) sensor was proposed for dopamine (DA) detection based on ruthenium(II) complex (tris(2,2-bipyridyl)dichlororuthenium(II) hexahydrate, Ru(bpy)₃²⁺) functionalized Zn(II) metal–organic frameworks (Ru-MOFs).

DNA–Cu(II) complexes lose their peroxidase-like activities after the cleavage of DNA scaffolds by S1 nuclease.

In this work, a new mode of dispersive solid-phase extraction named syringe to syringe magnetic dispersive micro-solid phase extraction is presented as an efficient and eco-friendly sample extraction method.

An analytical technique that employs in situ methanation with flame ionization detection for the measurement of carbon dioxide in various matrices has been developed and implemented.

In this experimental study, we developed lateral flow immunoassay strips for the detection of Escherichia coli.

In this work, samples of natural polyphenolic extracts, representing six commercially available types, were analysed by visible, ultraviolet and Fourier transform infrared (FTIR) spectroscopy using a classification technique.

Phthalates are a group of compounds widely used in consumer products and they are ubiquitous in the environment due to their widespread commercial use.

A LAMP-based method for the visual detection of Listeria monocytogenes has been developed by employing DNAzyme-catalyzed cascade amplification of the colorimetric signal.

A central composite design was applied to evaluate different sorbents in BAμE for the determination of emerging contaminants in water by UHPLC-MS/MS.

Brazilwood-derived pigments and dyes are found in many historical objects, from European paintings to North American First Nations textiles.

For the first time, a FRET nanosensor for AA was developed using GQDs as the energy donors and SQA-iron(III) as the energy acceptors.

In this study, we developed a lysosome-targeting fluorescent probe, 3-(2,4-dinitrophenoxy)-2-(4-morpholinophenyl)-4H-chromen-4-one (DMC), for the detection of hydrogen sulfide (H₂S) based on excited-state intramolecular proton transfer (ESIPT).

Graphene oxide enhanced SPR sensor for specific gravity detection of food analytes.

A polystyrene–PDMS device utilizing an embedded fused silica capillary and electrochemical detection was used for improved efficiency separations of catecholamines.

The analytical performances of a lateral flow immunoassay (AFLA-V AQUA™, Vicam a Waters Business) for the determination of aflatoxins in maize were evaluated according to Commission Regulation (EU) No. 519/2014.

Herein, an ultrasensitive and stereo-selective electrochemiluminescent (ECL) biosensor based on ECL signal amplification of luminol by the synergetic catalysis of a hemin-functionalized composite and gold–platinum nanowires (Au-PtNWs) has been designed for the detection of D-alanine (D-Ala).

Multi-functional hybrid nanoparticles are synthesized for fluorescence-SERS bimodal imaging of GPR120 in vitro.

A sensitive and selective photoelectrochemical sensor for the detection of Cu²⁺ in human serum samples based on the TiO₂/CdS nanorod array was reported.

Bimetallic gold/silver nanoclusters were synthesized in aqueous solution with lysozyme as a stabilizing and reducing agent.

A novel electrochemical sensor based on a poly-L-cysteine/graphene platform was developed for the simultaneous determination of dopamine and ascorbic acid.

A glassy carbon electrode surface was modified with a new combination of chitosan, single walled carbon nanotubes (SWCNT) and neodymium(III) oxide (NdOX) and was found to be effective in the detection of rutin (RU).

Selective alizarin red S detection based on the layered double hydroxides-improved chemiluminescence from hydrogen peroxide and luminol is presented.

Electrophoretic deposition (EPD) was hyphenated with electrochemical anodization for the fabrication of phenyl modified mesoporous silica (MPS-Ph) particles onto Nitinol (NiTi) wire as a solid-phase microextraction (SPME) fiber.

A forward interval variable selection algorithm combined with data fusion was developed to determine farinograph parameters of wheat flour.

Fenton-like reaction-mediated quenching of gold nanoclusters for ultrafast Cu²⁺ ion detection.

In this work, a NiO–CNT nanocomposite and 2-(3,4-dihydroxyphenethyl)isoindoline-1,3-dione (DPID) were used as modifiers for the modification of a carbon paste electrode (DPID/NiO–CNT/CPE) for the electro-catalytic analysis of glutathione (GSH).

Ultrasonic spectroscopy is a viable complement to current techniques used to analyze insulin stability due to its simplicity, lack of sample preparation, and non-destructive properties.

A novel colorimetric DMPD assay was developed for superoxide radicals generated by the NADH/PMS/O₂ system, and compared with conventional NBT assay.

The contribution of sampling to the combined uncertainty of measurement is assessed using a combination of literature review and experimental determination of sampling variability in a range of foodstuffs in order to determine whether there is a consistent relationship between analyte level and proportion of variation attributable to sampling.

The project aim was to identify differences in the metabolomic profiles in the serum of patients with multiple sclerosis (MS), those with neuropathic pain (NP) and those with both MS and NP compared with controls and to identify potential biomarkers of each disease state.

A novel ratiometric fluorescent nanosensor for visual sensing of Fe³⁺ has been developed by integrating yellow-emissive rhodamine derivatives (RhB) onto the surface of silica nanospheres embedded with red CdTe QDs.

Rapid detection and characterization of the major chemical constituents from Ardisia gigantifolia by HPLC-ESI-QTOF-MS/MS.

A FRET system was successfully constructed using supercharged green fluorescent protein as the energy donor and dye labelled heparin as the energy acceptor. The FRET sensing platform can be used to detect OSCS contaminant in heparin.

A novel strategy for the fabrication of a photoelectrochemical system, involving a duo-dye sensitized Au NPs composite, that displays a specific response to mercury.

Microfluidic equivalents of electrical resonant circuits exhibit predicted resonance behavior in both magnitude and phase of the harmonic flow as evidenced by two independent characterization techniques.

Sample pre-treatment by magnetic solid phase extraction based on a 3D reduced graphene oxide composite.

Cocoa beans were quality graded innovatively using a near-infrared chemo-dyes system as aroma sensor to capture and detect their volatiles.

This work reported a strategy of combining enzyme/DNAzyme amplification and guanine nanowires to develop a bioassay for Hg²⁺ detection.

Advantages of combined image analysis were demonstrated using infrared spectroscopy and mass spectrometry while characterizing biochemical changes occurring in tumor models.

An anthracene carboxyimide-based fluorescent probe was developed for rapid detection of formaldehyde in living cells with high sensitivity and selectivity.

A signal-off aptasensor for OTA detection at an apt/cDNA/AuNPs/cPC/NH₂–AuE electrode using methylene blue as an electrochemical probe.

A dual sensing probe for quantitation of NO₂⁻ and CN⁻ ions.

A new method has been developed for estimating relative oxygen metabolic activity microdistribution in biofilms based on catastrophe points during oxygen-infusion processes.

The LC-MS bioanalysis of protein kinetics assays is simplified by a data normalization strategy via internal proteolytic analyte utilized as a control standard.

Rapid and sensitive detection of E. coli O157:H7 based on antimicrobial peptide functionalized magnetic nanoparticles and label-free urease-catalyzed signal amplification.

Unexpected ionization processes were recently discovered for use in mass spectrometry in which no added energy is required to convert condensed-phase molecules to gas-phase ions with ESI-like charge states by simply introducing the matrix/analyte sample into the sub-atmospheric pressure of the mass spectrometer.

The temporal profiles of ion signals were measured for probe electrospray ionization (PESI) and nano-electrospray ionization (nESI) by changing the pulse width of the high voltage applied to the emitters.

We uncovered previously unknown metabolic differences between dorsal and ventral cells in the 8-cell vertebrate embryo using microprobe single-cell CE-ESI-MS.

Subcritical water extraction (SWE), a ‘green’ and efficient extraction technology, was applied to extract phenolic antioxidants from pomegranate peel in this study.

This work describes two novel validated HPLC methods for the separation and determination of potent antioxidant formulation.

In this study, third generation dendrimers covalently bonded to magnetic graphene oxide nanosheets (DMGO) were prepared.

A new sensor using a glassy carbon electrode modified with graphene and Au nanoparticles (Gr/Au/GCE) was designed to investigate the electrochemical behavior of furazolidone (FZD).

An FTIR-based multivariate approach is developed for monitoring molecular weight distribution during enzymatic protein hydrolysis of byproducts.

MIR microscopic imaging with subsequent PCA clustering is a very promising tool for the detection and identification of mucormycetes in pathology routine laboratories.