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Hazardous Reagent Substitution: A Pharmaceutical Perspective Editors: Rakesh Kumar Sharma, Rakeshwar Bandichhor


About this book

In recent years, a significant amount of progress has been made using green chemistry in the synthesis of synthetically useful compounds and molecules by replacing hazardous chemicals with greener alternatives. However, there is still room for improvement, especially in the pharmaceutical sector where new drugs are being formulated. This book examines green approaches to overcoming hazardous organic transformations. Summarizing recent developments, the book features a detailed description of some of the high impact active pharmaceutical ingredients that have been developed considering green chemistry approaches. It explores the design, engineering and process development and the calculations to account for waste. The book includes strategies to further advance green approaches in the development of generic pharmaceutical industries and features novel, innovative approaches that promote waste-free organic synthesis. This book is of interest to industrialists working in pharmaceuticals and researchers working in green chemistry.

From the book series:
Green Chemistry Series

Book content

  • Introduction to Hazardous Reagent Substitution in Pharmaceutical Industry
  • Classifications of Reagents
  • Recyclability of reagents
  • Synthesis of Saxagliptin
  • Synthesis of Raloxifene
  • Synthesis of Montelukast
  • Synthesis of Gemcitabine
  • Synthesis of Clopidogrel
  • Synthesis of Ritonavir
  • Synthesis of Valsartan
  • Synthesis of Naproxen
  • New Directions from Academia.

The print version of this book is planned for release on 14 December 2017. Information about this book is subject to change without notice.

Pre-order hardback £149.00 *
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This book contains 183 pages.

Publication details

Copyright year: 2018
Print ISBN: 978-1-78262-050-1
Citation: