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Chapter 11

Nuclear Magnetic Resonance Case Studies in Marine Natural Products

Marine natural products represent a remarkably diverse array of structure classes, many featuring “first-in-class” carbon skeletons, heterocycles, and functionality, further elaborated with stereochemical complexity. Typically isolated in low yields from complex natural extracts, these metabolites can be unstable and prone to rearrangement and/or degradation during handling and storage, and particularly during spectroscopic analysis. This chapter uses a number of case studies from the authors’ laboratory to illustrate some of the challenges encountered and benefits that arise from using NMR in the structure elucidation of marine natural products.

Print publication date: 14 Dec 2016
Copyright year: 2017
Print ISBN: 978-1-84973-393-9
PDF eISBN: 978-1-84973-468-4
ePub eISBN: 978-1-78801-072-6
Citation: