Issue 58, 2024

Alkyl nitrite-enabled palladium-catalyzed terminal selective oxidative cyclization of 4-penten-1-ols

Abstract

Oxidative cyclization of 4-penten-1-ols using a Pd catalyst and n-BuONO or n-BuONO/p-benzoquinone afforded 3-hydroxy- and 3-methoxytetrahydropyrans via terminal selective nucleophilic attack. The radicals formed from n-BuONO and O2 operate as critical oxidants and ligands for Pd.

Graphical abstract: Alkyl nitrite-enabled palladium-catalyzed terminal selective oxidative cyclization of 4-penten-1-ols

Supplementary files

Article information

Article type
Communication
Submitted
20 May 2024
Accepted
24 Jun 2024
First published
24 Jun 2024

Chem. Commun., 2024,60, 7495-7498

Alkyl nitrite-enabled palladium-catalyzed terminal selective oxidative cyclization of 4-penten-1-ols

A. Iwanami, S. Komori and Y. Ura, Chem. Commun., 2024, 60, 7495 DOI: 10.1039/D4CC02451F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements