Visualization diagnosis of acute cerebral ischemia via sulfane sulfur-activated photoacoustic imaging

Cheng Song; Lejuan Liao; Yidong Bin; Zongyi He; Jing Hua; Shulin Zhao; Hong Liang

doi:10.1039/D3CC05794A

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Visualization diagnosis of acute cerebral ischemia via sulfane sulfur-activated photoacoustic imaging†

Cheng Song,^a Lejuan Liao,^a Yidong Bin,^a Zongyi He,^a Jing Hua,^a Shulin Zhao

*^a and Hong Liang*^a

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* Corresponding authors

^a State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin 541004, China
E-mail: zhaoshulin001@163.com, hliang@gxnu.edu.cn

Abstract

A photoacoustic (PA) imaging probe, HCy-SH, was designed and synthesized. This probe can react rapidly and specifically with sulfane sulfur to produce a strong PA signal. This probe also exhibited low cytotoxicity and biotoxicity. Thus, HCy-SH has been used for visual diagnosis of acute cerebral ischemia.

This article is part of the themed collection: Chemical Communications HOT Articles 2024

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DOI: https://doi.org/10.1039/D3CC05794A
Article type: Communication
Submitted: 27 Nov 2023
Accepted: 18 Dec 2023
First published: 22 Dec 2023

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Chem. Commun., 2024,60, 1112-1115

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Visualization diagnosis of acute cerebral ischemia via sulfane sulfur-activated photoacoustic imaging

C. Song, L. Liao, Y. Bin, Z. He, J. Hua, S. Zhao and H. Liang, Chem. Commun., 2024, 60, 1112 DOI: 10.1039/D3CC05794A

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Chemical Communications

Visualization diagnosis of acute cerebral ischemia via sulfane sulfur-activated photoacoustic imaging†

Abstract

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Visualization diagnosis of acute cerebral ischemia via sulfane sulfur-activated photoacoustic imaging

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