A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins

Jiefang Chen; Furong Gao; Zhongren Xu; Yuanhao Liu; Ming Hu; Chengyi Yuan; Yunhua Zhang; Wukun Liu; Xiaohui Wang

doi:10.1039/D3CC05680E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A terbium(iii) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins†

Jiefang Chen,^a Furong Gao,^a Zhongren Xu,^b Yuanhao Liu,^b Ming Hu,*^a Chengyi Yuan,^a Yunhua Zhang,^c Wukun Liu^b and Xiaohui Wang

*^ac

Author affiliations

* Corresponding authors

^a Institute of Chemical Biology and Functional Molecules, State Key Laboratory of Materials-Oriented Chemical Engineering, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, P. R. China
E-mail: wangxhui@njtech.edu.cn, huming@njtech.edu.cn

^b School of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, P. R. China

^c State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, P. R. China

Abstract

A terbium(III) complex-based time-resolved luminescence probe for selenocysteine can inhibit selenoprotein activity via a selenolate-triggered cleavage reaction of sulfonamide bonds in living cells.

Download options Please wait...

Supplementary files

Supplementary information PDF (1622K)

Article information

DOI: https://doi.org/10.1039/D3CC05680E
Article type: Communication
Submitted: 20 Nov 2023
Accepted: 03 Jan 2024
First published: 03 Jan 2024

Download Citation

Chem. Commun., 2024,60, 1440-1443

Permissions

Request permissions

A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins

J. Chen, F. Gao, Z. Xu, Y. Liu, M. Hu, C. Yuan, Y. Zhang, W. Liu and X. Wang, Chem. Commun., 2024, 60, 1440 DOI: 10.1039/D3CC05680E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

A terbium(iii) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins†

Abstract

Supplementary files

Article information

Download Citation

Permissions

A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins

Social activity

Search articles by author

Spotlight

Advertisements