Issue 6, 2023

A concise synthesis of thioaurones via NBS-induced cyclization of MOM-protected 2′-mercaptochalcones

Abstract

A mild and efficient approach for the synthesis of thioaurones via NBS-induced cyclization of methoxymethyl-protected mercapto-chalcones has been developed. This simple method is highly functional group tolerant and provides straightforward access to thioaurones in good to high yields.

Graphical abstract: A concise synthesis of thioaurones via NBS-induced cyclization of MOM-protected 2′-mercaptochalcones

Supplementary files

Article information

Article type
Communication
Submitted
02 Nov 2022
Accepted
02 Dec 2022
First published
05 Dec 2022

Org. Biomol. Chem., 2023,21, 1134-1137

A concise synthesis of thioaurones via NBS-induced cyclization of MOM-protected 2′-mercaptochalcones

A. Nakamura, F. Rao, K. Ukiya, R. Matsunaga, S. Ohira and T. Maegawa, Org. Biomol. Chem., 2023, 21, 1134 DOI: 10.1039/D2OB01995G

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