Issue 15, 2022
From the journal:

Analyst

Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells†

Hui Yuan,a   Jiuming Sun,a   Qi Zhang,a   Mingyue Chu,a   Guiguang Cheng,b   Xia Li ORCID logo *a  and  Qingwang Xue ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Liaocheng University, Liaocheng, Shandong, China
E-mail: lixia@lcu.edu.cn, xueqingwang1983@163.com
Fax: +86-635-8239001
Tel: +86-635-8239001

b Faculty of Agriculture and Food, Kunming University of Science and Technology, Kunming, China

Abstract

Highly sensitive and reliable PEC detection of miRNAs still faces some challenges like the inaccuracy caused by coexisting interferences in the PEC system. Herein, we developed a split-type “turn-off” PEC biosensor based on spatially-extended 3D magnetic DNA nanodevices with high-order DNA amplifiers for sensitive detection of miRNAs in cancer cells.

Graphical abstract: Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells

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Article information

DOI
https://doi.org/10.1039/D2AN00712F
Article type
Communication
Submitted
26 Apr 2022
Accepted
01 Jun 2022
First published
10 Jun 2022

Analyst, 2022,147, 3415-3419

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Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells

H. Yuan, J. Sun, Q. Zhang, M. Chu, G. Cheng, X. Li and Q. Xue, Analyst, 2022, 147, 3415 DOI: 10.1039/D2AN00712F

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