Recent advances and future challenges in the synthesis of 2,4,6-triarylpyridines

Abstract

2,4,6-Triarylpyridines are key building blocks to access functional molecules that are used in the design of advanced materials, metal–organic frameworks, supramolecules, reactive chemical intermediates and drugs. A number of synthetic protocols to construct this heterocyclic scaffold have been developed to date, the most recent of which (2015–present) are included and discussed in the present review. An emphasis has been placed on the utility of each synthetic approach in view of the scope of aryl/hetaryl substituents, limitations and an outlook of each method to be used in applied sciences.