Issue 26, 2021

Ag–Cu copromoted direct C2–H bond thiolation of azoles with Bunte salts as sulfur sources

Abstract

A direct C2–H thiolation of azoles with Bunte salts was achieved under the combined action of copper and silver salts. This protocol could furnish various substituted 2-thioazoles in moderate to good yields. This method has a broad substrate scope and shows good functional group tolerance.

Graphical abstract: Ag–Cu copromoted direct C2–H bond thiolation of azoles with Bunte salts as sulfur sources

Supplementary files

Article information

Article type
Paper
Submitted
28 Apr 2021
Accepted
04 Jun 2021
First published
04 Jun 2021

Org. Biomol. Chem., 2021,19, 5899-5904

Ag–Cu copromoted direct C2–H bond thiolation of azoles with Bunte salts as sulfur sources

R. Wang, H. Xu, Y. Zhang, Y. Hu, Y. Wei, X. Du and H. Zhao, Org. Biomol. Chem., 2021, 19, 5899 DOI: 10.1039/D1OB00823D

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