In 2015, we proposed FRET nanoflares for intracellular molecular (RNA, H+, and K+) detection. To improve detection accuracy and achieve on-demand sensing, herein, we developed photocaged FRET nanoflares for spatiotemporal microRNA imaging in living cells. In other words, the probes will not work until they are exposed to UV light.
J. Li, S. Cai, B. Zhou, X. Meng, Q. Guo, X. Yang, J. Huang and K. Wang, Chem. Commun., 2020, 56, 6126 DOI: 10.1039/D0CC02395G
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