Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles

Wen Bao; Zhu-Peng Gao; Da-Ping Jin; Cao-Gen Xue; Huan Liang; Ling-Sheng Lei; Xue-Tao Xu; Kun Zhang; Shao-Hua Wang

doi:10.1039/D0CC01591A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles†‡

Wen Bao,^a Zhu-Peng Gao,^a Da-Ping Jin,^a Cao-Gen Xue,^a Huan Liang,^a Ling-Sheng Lei,^a Xue-Tao Xu,

^b Kun Zhang^b and Shao-Hua Wang

*^ab

Author affiliations

* Corresponding authors

^a School of Pharmacy & State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
E-mail: wangshh@lzu.edu.cn

^b School of Biotechnology and Health Science, Wuyi University, Jiangmen 529020, P. R. China

Abstract

An efficient alkylcyanation of in situ generated arynes by N,N-disubstituted aminomalononitriles is described, enabling the direct synthesis of 2-substituted benzonitriles.

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/D0CC01591A
Article type: Communication
Submitted: 29 Feb 2020
Accepted: 22 May 2020
First published: 25 May 2020

Download Citation

Chem. Commun., 2020,56, 7641-7644

Permissions

Request permissions

Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles

W. Bao, Z. Gao, D. Jin, C. Xue, H. Liang, L. Lei, X. Xu, K. Zhang and S. Wang, Chem. Commun., 2020, 56, 7641 DOI: 10.1039/D0CC01591A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles†‡

Abstract

Supplementary files

Article information

Download Citation

Permissions

Direct synthesis of 2-substituted benzonitriles via alkylcyanation of arynes with N,N-disubstituted aminomalononitriles

Social activity

Search articles by author

Spotlight

Advertisements