Rhodium(iii)-catalyzed diamidation of olefins via amidorhodation and further amidation

Abstract

Rh(III)-catalyzed synthesis of vicinal diamides has been realized via elaboration of an authenticated Rh–C(sp³) species generated via initial intramolecular amidorhodation of olefins. The second amidation was achieved using both electrophilic and nucleophilic amidating reagents. The reactions proceeded under mild conditions with good yield, broad substrate scope, and excellent functional-group tolerance.