Issue 25, 2019

Enantioselective vinylogous Michael addition of β,γ-unsaturated butenolide to 2-iminochromenes

Abstract

An efficient organocatalyzed asymmetric synthesis of 2-amino-4-(2-furanone)-4H-chromene-3-carbonitriles via vinylogous Michael addition of non-activated β,γ-unsaturated butenolide to 2-iminochromenes has been realized.

Graphical abstract: Enantioselective vinylogous Michael addition of β,γ-unsaturated butenolide to 2-iminochromenes

Supplementary files

Article information

Article type
Letter
Submitted
27 Mar 2019
Accepted
04 Jun 2019
First published
04 Jun 2019

New J. Chem., 2019,43, 9771-9775

Enantioselective vinylogous Michael addition of β,γ-unsaturated butenolide to 2-iminochromenes

V. Gupta and R. P. Singh, New J. Chem., 2019, 43, 9771 DOI: 10.1039/C9NJ01584A

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