Cascade intramolecular imidoylation and C–H activation/annulation of benzimidoyl chlorides with alkynes: one-pot synthesis of 7H-dibenzo[de,h]quinoline analogues

Abstract

Reported herein is a cascade Lewis acid-promoted intramolecular Friedel–Crafts-type imidoylation and Rh(III)-catalyzed C–H activation/annulation of benzimidoyl chlorides and alkynes, providing a general and concise one-pot approach to 7H-dibenzo[de,h]quinoline analogues. This divergent approach is based on a convergent retrosynthetic disconnection strategy.