A triply-responsive supramolecular vesicle fabricated by α-cyclodextrin based host–guest recognition and double dynamic covalent bonds

Abstract

The supramolecular construction of multi-stimuli assemblies is a challenging task for prospective use. In this work, a novel supramolecular amphiphile was fabricated by introducing molecules with dynamic covalent bonds into host–guest inclusion. The amphiphile formed a vesicle, which was characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), ¹H NMR and UV-vis spectra. Furthermore, the vesicular structure could be regulated by pH, light and redox reagent, and thus the loaded dye in the vesicles could be released in a controlled manner.