Spinach-based fluorescent light-up biosensors for multiplexed and label-free detection of microRNAs

Zhan-Ming Ying; Bin Tu; Lan Liu; Hao Tang; Li-Juan Tang; Jian-Hui Jiang

doi:10.1039/C8CC00123E

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Spinach-based fluorescent light-up biosensors for multiplexed and label-free detection of microRNAs†

Zhan-Ming Ying,^a Bin Tu,^a Lan Liu,^a Hao Tang,

*^a Li-Juan Tang^a and Jian-Hui Jiang

*^a

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* Corresponding authors

^a Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China
E-mail: haotang@hnu.edu.cn, jianhuijiang@hnu.edu.cn
Fax: 86-731-88822872
Tel: 86-731-88822577

Abstract

A novel Spinach-based fluorescent light-up biosensor utilizing the T7 in vitro transcription process to generate unmodified Spinach sequences for multiplexed microRNA detection has been developed.

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Article information

DOI: https://doi.org/10.1039/C8CC00123E
Article type: Communication
Submitted: 06 Jan 2018
Accepted: 23 Feb 2018
First published: 23 Feb 2018

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Chem. Commun., 2018,54, 3010-3013

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Spinach-based fluorescent light-up biosensors for multiplexed and label-free detection of microRNAs

Z. Ying, B. Tu, L. Liu, H. Tang, L. Tang and J. Jiang, Chem. Commun., 2018, 54, 3010 DOI: 10.1039/C8CC00123E

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Chemical Communications

Spinach-based fluorescent light-up biosensors for multiplexed and label-free detection of microRNAs†

Abstract

Supplementary files

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Spinach-based fluorescent light-up biosensors for multiplexed and label-free detection of microRNAs

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