Issue 53, 2017
From the journal:

Chemical Communications

Exhaustive Suzuki–Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters†

Sébastien Laulhé,‡a   J. Miles Blackburn‡b  and  Jennifer L. Roizen ORCID logo *b  

* Corresponding authors

a Department of Chemistry and Chemical Biology, IUPUI, Indianapolis, IN 46202, USA

b Duke University, Department of Chemistry, Box 90346, Durham, North Carolina 27708-0354, USA
E-mail: j.roizen@duke.edu

Abstract

A novel Suzuki–Miyaura protocol is described that enables the exhaustive alkylation of polychlorinated pyridines. This method facilitates a formal synthesis of normuscopyridine and the rapid assembly of a dumbbell shaped portion of a [2]rotaxane.

Graphical abstract: Exhaustive Suzuki–Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7CC00997F
Article type
Communication
Submitted
07 Feb 2017
Accepted
28 Feb 2017
First published
03 Mar 2017

Chem. Commun., 2017,53, 7270-7273

Permissions

Request permissions

Exhaustive Suzuki–Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters

S. Laulhé, J. M. Blackburn and J. L. Roizen, Chem. Commun., 2017, 53, 7270 DOI: 10.1039/C7CC00997F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements