Issue 13, 2017

Enzymatically activated reduction-caged SERS reporters for versatile bioassays

Abstract

Here we report a facile strategy for activating reduction caged Raman reporters for surface-enhanced Raman scattering (SERS) with peroxidases. After selecting suitable caged reporters, versatile bioassays were developed. First, the bioassays for bioactive small molecules were developed. Then, the immunoassay was developed for C reactive protein (CRP), a biomarker for cardiovascular diseases.

Graphical abstract: Enzymatically activated reduction-caged SERS reporters for versatile bioassays

Supplementary files

Article information

Article type
Communication
Submitted
01 Apr 2017
Accepted
13 May 2017
First published
17 May 2017

Analyst, 2017,142, 2322-2326

Enzymatically activated reduction-caged SERS reporters for versatile bioassays

W. Guo, Y. Hu and H. Wei, Analyst, 2017, 142, 2322 DOI: 10.1039/C7AN00552K

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