Issue 6, 2017

Synthesis and functionalization of dextran-based single-chain nanoparticles in aqueous media

Abstract

Water-dispersible dextran-based single-chain polymer nanoparticles (SCPNs) were prepared in aqueous media and under mild conditions. Radiolabeling of the resulting biocompatible materials allowed the study of lung deposition of aqueous aerosols after intratracheal nebulization by means of single-photon emission computed tomography (SPECT), demonstrating their potential use as imaging contrast agents.

Graphical abstract: Synthesis and functionalization of dextran-based single-chain nanoparticles in aqueous media

Supplementary files

Article information

Article type
Communication
Submitted
24 Oct 2016
Accepted
15 Jan 2017
First published
16 Jan 2017

J. Mater. Chem. B, 2017,5, 1143-1147

Synthesis and functionalization of dextran-based single-chain nanoparticles in aqueous media

R. Gracia, M. Marradi, U. Cossío, A. Benito, A. Pérez-San Vicente, V. Gómez-Vallejo, H.-J. Grande, J. Llop and I. Loinaz, J. Mater. Chem. B, 2017, 5, 1143 DOI: 10.1039/C6TB02773C

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