Issue 6, 2017
From the journal:

Chemical Communications

Synthesis of chiral (tetrazolyl)methyl-containing acrylates via silicon-induced organocatalytic kinetic resolution of Morita–Baylis–Hillman fluorides†

Takayuki Nishimine,a   Hiromi Taira,a   Satoru Mori,a   Okiya Matsubara,a   Etsuko Tokunaga,a   Hidehiko Akiyama,b   Vadim A. Soloshonokcd  and  Norio Shibata ORCID logo *a  

* Corresponding authors

a Department of Nanopharmaceutical Sciences & Department of Frontier Materials, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan
E-mail: nozshiba@nitech.ac.jp

b Faculty of Medical Technology, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Japan

c Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, Paseo Manuel Lardizábal 3, 20018 San Sebastián, Spain

d IKERBASQUE, Basque Foundation for Science, Alameda Urquijo 36-5, Plaza Bizkaia, Spain

Abstract

Reported herein is a new approach for the asymmetric installation of a (tetrazolyl)methyl group via Si/F activation using organocatalytic kinetic resolution of racemic MBH-fluorides.

Graphical abstract: Synthesis of chiral (tetrazolyl)methyl-containing acrylates via silicon-induced organocatalytic kinetic resolution of Morita–Baylis–Hillman fluorides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6CC08830A
Article type
Communication
Submitted
04 Nov 2016
Accepted
21 Dec 2016
First published
21 Dec 2016

Chem. Commun., 2017,53, 1128-1131

Permissions

Request permissions

Synthesis of chiral (tetrazolyl)methyl-containing acrylates via silicon-induced organocatalytic kinetic resolution of Morita–Baylis–Hillman fluorides

T. Nishimine, H. Taira, S. Mori, O. Matsubara, E. Tokunaga, H. Akiyama, V. A. Soloshonok and N. Shibata, Chem. Commun., 2017, 53, 1128 DOI: 10.1039/C6CC08830A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements