Issue 2, 2016

The regulatory function of microRNA-1 in arrhythmias

Abstract

Arrhythmia, the basis of which is cardiomyocyte ion channel abnormalities, poses a serious threat to human health. A large number of studies have demonstrated that miRNA-1(miR-1) is involved in the occurrence of arrhythmia in many myocardial pathological conditions by post-transcriptionally regulating a variety of ion channels and proteins related to cardiac electrical activity. We aim at emphasizing the relationship between miR-1 and ion channels and proteins involved in the process of arrhythmia. In addition, we will pay attention to its future therapeutic prospects.

Graphical abstract: The regulatory function of microRNA-1 in arrhythmias

Article information

Article type
Review Article
Submitted
22 Nov 2015
Accepted
25 Nov 2015
First published
25 Nov 2015

Mol. BioSyst., 2016,12, 328-333

Author version available

The regulatory function of microRNA-1 in arrhythmias

C. Liao, Y. Gui, Y. Guo and D. Xu, Mol. BioSyst., 2016, 12, 328 DOI: 10.1039/C5MB00806A

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