Issue 62, 2016, Issue in Progress
From the journal:

RSC Advances

Supramolecular nanofibers of self-assembling peptides and DDP to inhibit cancer cell growth†

Xiaoli Zhang,a   Can Li,a   Youzhi Wang, ORCID logo a   Caiwen Ou,b   Shenglu Ji,a   Minsheng Chen*b  and  Zhimou Yang*a  

* Corresponding authors

a State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education and College of Life Sciences, Nankai University and Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, P. R. China
E-mail: yangzm@nankai.edu.cn

b Department of Cardiology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, P. R. China
E-mail: gzminsheng@vip.163.com

Abstract

We report in this paper a molecular hydrogel formed by adding cis-dichlorodiamineplatinum(II) (DDP) to a self-assembling taxol-peptide amphiphile. Our study provides a novel self-assembling nanomedicine and hydrogel to deliver two anti-cancer drugs simultaneously.

Graphical abstract: Supramolecular nanofibers of self-assembling peptides and DDP to inhibit cancer cell growth

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Article information

DOI
https://doi.org/10.1039/C6RA08357A
Article type
Communication
Submitted
01 Apr 2016
Accepted
07 Jun 2016
First published
08 Jun 2016

RSC Adv., 2016,6, 56903-56906

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Supramolecular nanofibers of self-assembling peptides and DDP to inhibit cancer cell growth

X. Zhang, C. Li, Y. Wang, C. Ou, S. Ji, M. Chen and Z. Yang, RSC Adv., 2016, 6, 56903 DOI: 10.1039/C6RA08357A

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