Issue 50, 2016, Issue in Progress
From the journal:

RSC Advances

A theophylline based copper N-heterocyclic carbene complex: synthesis and activity studies in green media†

Anna Szadkowska,*a   Sebastian Staszko,ab   Ewelina Zaorskaa  and  Robert Pawłowskiac  

* Corresponding authors

a Department of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland
E-mail: szadkowska.anna@gmail.com

b Faculty of Advanced Technologies and Chemistry, Military University of Technology, them. Jaroslaw Dabrowski, gen. Sylvester Kaliski 2, 00-908 Warsaw 49, Poland

c Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland

Abstract

The synthesis of an easily accessible theophylline-derived copper complex with additional ammonium functionalization has been developed. This xanthine-based metal compound turned out to be an active initiator of the alkyne–azide cycloaddition reaction (CuAAC) and Glaser homo-coupling reaction in aqueous media at room temperature.

Graphical abstract: A theophylline based copper N-heterocyclic carbene complex: synthesis and activity studies in green media

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Article information

DOI
https://doi.org/10.1039/C6RA06682H
Article type
Communication
Submitted
13 Mar 2016
Accepted
26 Apr 2016
First published
04 May 2016

RSC Adv., 2016,6, 44248-44253

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A theophylline based copper N-heterocyclic carbene complex: synthesis and activity studies in green media

A. Szadkowska, S. Staszko, E. Zaorska and R. Pawłowski, RSC Adv., 2016, 6, 44248 DOI: 10.1039/C6RA06682H

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