Issue 16, 2015

Accessible protocol for asymmetric hydroformylation of vinylarenes using formaldehyde

Abstract

We report herein on an accessible protocol for the asymmetric hydroformylation of vinylarenes using formaldehyde as a substitute for syngas. The regioselectivity (branched/linear = up to 96/4) and enantioselectivity (up to 95% ee) can be attributed to the use of chiral Ph-bpe as a ligand.

Graphical abstract: Accessible protocol for asymmetric hydroformylation of vinylarenes using formaldehyde

Supplementary files

Article information

Article type
Communication
Submitted
25 Feb 2015
Accepted
12 Mar 2015
First published
12 Mar 2015

Org. Biomol. Chem., 2015,13, 4632-4636

Author version available

Accessible protocol for asymmetric hydroformylation of vinylarenes using formaldehyde

T. Morimoto, T. Fujii, K. Miyoshi, G. Makado, H. Tanimoto, Y. Nishiyama and K. Kakiuchi, Org. Biomol. Chem., 2015, 13, 4632 DOI: 10.1039/C5OB00378D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements