Issue 17, 2015

A reusable ratiometric two-photon chemodosimeter for Hg2+ detection based on ESIPT and its application in bioimaging

Abstract

A novel ratiometric fluorescent chemodosimeter has been developed for reusable detection of Hg2+. The chemodosimeter responds to Hg2+ sensitively and selectively with a remarkable fluorescence change from green to blue through hampering the excited state intramolecular proton transfer (ESIPT) process. This recyclable chemodosimeter can remove Hg2+ from water by forming a unique mercury-containing compound, which could be reused in the presence of NaBH4. Moreover, the chemodosimeter exhibits a ratiometric fluorescence response to Hg2+ with a very low detection limit (1.0 ppb), and it can be used to detect Hg2+ in drinking water. Furthermore, the ratiometric chemodosimeter has been successfully used for imaging Hg2+ in living cells and tissues using two-photon fluorescence microscopy due to the remarkable emission change from green to blue. This provides a novel testing method for detecting Hg2+ in living cells and tissues with low cytotoxicity and autofluorescence.

Graphical abstract: A reusable ratiometric two-photon chemodosimeter for Hg2+ detection based on ESIPT and its application in bioimaging

Supplementary files

Article information

Article type
Paper
Submitted
28 Jan 2015
Accepted
13 Mar 2015
First published
13 Mar 2015

J. Mater. Chem. B, 2015,3, 3459-3464

Author version available

A reusable ratiometric two-photon chemodosimeter for Hg2+ detection based on ESIPT and its application in bioimaging

W. Luo, H. Jiang, K. Zhang, W. Liu, X. Tang, W. Dou, Z. Ju, Z. Li and W. Liu, J. Mater. Chem. B, 2015, 3, 3459 DOI: 10.1039/C5TB00203F

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