Issue 71, 2015

Copper promoted radical addition/cyclization of azobisisobutyronitrile with arylacrylamides: a convenient process to synthesize 3-(2′-cyano alkyl) oxindoles

Abstract

A CuI promoted radical addition/cyclization of azobisisobutyronitrile with alkenes was developed. The reaction provided a facile pathway for synthesis of 3-(2′-cyano alkyl) oxindoles. The cyano group is versatile for facile conversion into a diverse class of functionalities.

Graphical abstract: Copper promoted radical addition/cyclization of azobisisobutyronitrile with arylacrylamides: a convenient process to synthesize 3-(2′-cyano alkyl) oxindoles

Supplementary files

Article information

Article type
Paper
Submitted
28 Apr 2015
Accepted
25 Jun 2015
First published
25 Jun 2015

RSC Adv., 2015,5, 57469-57471

Author version available

Copper promoted radical addition/cyclization of azobisisobutyronitrile with arylacrylamides: a convenient process to synthesize 3-(2′-cyano alkyl) oxindoles

R. Wang and W. Bao, RSC Adv., 2015, 5, 57469 DOI: 10.1039/C5RA07739G

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