Issue 6, 2015
From the journal:

RSC Advances

A convenient synthetic route to sulfonimidamides from sulfonamides†

Yantao Chen*a  and  James Gibsona  

* Corresponding authors

a AstraZeneca Innovative Medicines Cardiovascular and Metabolic Diseases, S-431 83 Mölndal, Sweden
E-mail: yantao.chen@astrazeneca.com, yantaochen.se@gmail.com
Fax: +46-31-776-3710
Tel: +46-31-706-5577

Abstract

Sulfonimidamides were prepared in a one-pot transformation from sulfonamides, through nucleophilic substitution of sulfonimidoyl chlorides formed in situ with different amines. This methodology represents a convenient, safe, and easily accessible synthetic route to sulfonimidamides.

Graphical abstract: A convenient synthetic route to sulfonimidamides from sulfonamides

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Article information

DOI
https://doi.org/10.1039/C4RA14056G
Article type
Communication
Submitted
07 Nov 2014
Accepted
08 Dec 2014
First published
08 Dec 2014

RSC Adv., 2015,5, 4171-4174

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A convenient synthetic route to sulfonimidamides from sulfonamides

Y. Chen and J. Gibson, RSC Adv., 2015, 5, 4171 DOI: 10.1039/C4RA14056G

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