Issue 64, 2015
From the journal:

Chemical Communications

A ratiometric fluorescent system for carboxylesterase detection with AIE dots as FRET donors†

Yinglong Wu,a   Shuailing Huang,a   Fang Zeng,*a   Jun Wang,a   Changmin Yu,a   Jing Huang,a   Huiting Xiea  and  Shuizhu Wu*a  

* Corresponding authors

a College of Materials Science and Engineering, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P. R. China
E-mail: mcfzeng@scut.edu.cn, shzhwu@scut.edu.cn
Fax: +86 20 22236363
Tel: +86 20 22236262

Abstract

A ratiometric fluorescent system for CaE detection with AIE dots as the FRET donors was designed. Upon enzymatic reaction, electrostatic interaction between the cationic TPE-N+ dots and the enzymatic reaction product – the negatively charged fluorescein molecules – allows the FRET process to proceed, thus affording the ratiometric fluorescence CaE assay.

Graphical abstract: A ratiometric fluorescent system for carboxylesterase detection with AIE dots as FRET donors

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Article information

DOI
https://doi.org/10.1039/C5CC04771D
Article type
Communication
Submitted
10 Jun 2015
Accepted
07 Jul 2015
First published
07 Jul 2015

Chem. Commun., 2015,51, 12791-12794

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A ratiometric fluorescent system for carboxylesterase detection with AIE dots as FRET donors

Y. Wu, S. Huang, F. Zeng, J. Wang, C. Yu, J. Huang, H. Xie and S. Wu, Chem. Commun., 2015, 51, 12791 DOI: 10.1039/C5CC04771D

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