Issue 72, 2015
From the journal:

Chemical Communications

Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin†

Yuanwei Daia  and  Biao Yu*a  

* Corresponding authors

a State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P. R. China
E-mail: byu@mail.sioc.ac.cn
Fax: +86-21-64166128

Abstract

Astrosterioside A, a sulfated steroidal hexasaccharide isolated from starfish Astropecten monacanthus showing potent anti-inflammatory activity, was synthesized in a convergent linear sequence of 24 steps and in 6.8% overall yield from adrenosterone.

Graphical abstract: Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin

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Article information

DOI
https://doi.org/10.1039/C5CC04734J
Article type
Communication
Submitted
09 Jun 2015
Accepted
22 Jul 2015
First published
24 Jul 2015

Chem. Commun., 2015,51, 13826-13829

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Total synthesis of astrosterioside A, an anti-inflammatory asterosaponin

Y. Dai and B. Yu, Chem. Commun., 2015, 51, 13826 DOI: 10.1039/C5CC04734J

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