Issue 32, 2015
From the journal:

Chemical Communications

Nitric oxide releasing plasma polymer coating with bacteriostatic properties and no cytotoxic side effects†

Thomas D. Michl,*ab   Bryan R. Coad,b   Michael Doran,c   Michael Osiecki,c   Morteza Hasanzadeh Kafshgari,b   Nicolas H. Voelcker,b   Amanda Hüsler,a   Krasimir Vasilevb  and  Hans J. Griesserb  

* Corresponding authors

a Ian Wark Research Institute, University of South Australia, Mawson Lakes, SA 5095, Australia
E-mail: mictd002@mymail.unisa.edu.au

b Mawson Institute, University of South Australia, Mawson Lakes, SA 5095, Australia

c Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD 4059, Australia

Abstract

We report a stable plasma polymer coating, using isopentyl nitrite as a volatile precursor, which releases nitric oxide at bacteriostatic concentrations when contacted with water, inhibiting bacterial growth without cytotoxic side effects to human mesenchymal stem/stromal cells.

Graphical abstract: Nitric oxide releasing plasma polymer coating with bacteriostatic properties and no cytotoxic side effects

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Article information

DOI
https://doi.org/10.1039/C5CC01722J
Article type
Communication
Submitted
27 Feb 2015
Accepted
18 Mar 2015
First published
19 Mar 2015

Chem. Commun., 2015,51, 7058-7060

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Nitric oxide releasing plasma polymer coating with bacteriostatic properties and no cytotoxic side effects

T. D. Michl, B. R. Coad, M. Doran, M. Osiecki, M. H. Kafshgari, N. H. Voelcker, A. Hüsler, K. Vasilev and H. J. Griesser, Chem. Commun., 2015, 51, 7058 DOI: 10.1039/C5CC01722J

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