A biocompatible porous Mg-gallate metal–organic framework as an antioxidant carrier

Lucy Cooper; Tania Hidalgo; Martin Gorman; Tamara Lozano-Fernández; Rosana Simón-Vázquez; Camille Olivier; Nathalie Guillou; Christian Serre; Charlotte Martineau; Francis Taulelle; Daiane Damasceno-Borges; Guillaume Maurin; África González-Fernández; Patricia Horcajada; Thomas Devic

doi:10.1039/C5CC00745C

A biocompatible porous Mg-gallate metal–organic framework as an antioxidant carrier†

Lucy Cooper,‡^a Tania Hidalgo,‡^a Martin Gorman,^a Tamara Lozano-Fernández,^b Rosana Simón-Vázquez,^b Camille Olivier,^a Nathalie Guillou,^a Christian Serre,^a Charlotte Martineau,^a Francis Taulelle,^a Daiane Damasceno-Borges,^c Guillaume Maurin,^c África González-Fernández,^b Patricia Horcajada*^a and Thomas Devic*^a

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^a Institut Lavoisier, UMR CNRS 8180 Université de Versailles Saint-Quentin-en-Yvelines, 45 Av. des Etats-Unis, 78035 Versailles cedex, France
E-mail: patricia.horcajada-cortes@uvsq.fr, thomas.devic@uvsq.fr

^b Immunology, Biomedical Research Center (CINBIO) and Institute of Biomedical Research of Vigo (IBIV), Universidad de Vigo, Campus Lagoas Marcosende, 36310 Vigo, Pontevedra, Spain

^c Institut Charles Gerhardt Montpellier, UMR 5253 CNRS UM ENSCM Université de Montpellier, Place E. Bataillon, 34095 Montpellier cedex 05, France

Abstract

A microporous magnesium gallate MOF was prepared from highly biocompatible reagents under environmentally friendly conditions. Its slow degradation in physiological fluids leads to the release of gallic acid and hence a high antioxidant activity, which was illustrated in the HL-60 cell line.

Chemical Communications

A biocompatible porous Mg-gallate metal–organic framework as an antioxidant carrier†

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A biocompatible porous Mg-gallate metal–organic framework as an antioxidant carrier

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