Issue 29, 2015

meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

Abstract

Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.

Graphical abstract: meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

Supplementary files

Article information

Article type
Communication
Submitted
20 Jan 2015
Accepted
27 Feb 2015
First published
03 Mar 2015

Chem. Commun., 2015,51, 6369-6372

Author version available

meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

N. Rubinstein, P. Liu, E. W. Miller and R. Weinstain, Chem. Commun., 2015, 51, 6369 DOI: 10.1039/C5CC00550G

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