Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10−6 cm2 s−1) in the mouse brain.
C. W. Atcherley, K. M. Wood, K. L. Parent, P. Hashemi and M. L. Heien, Chem. Commun., 2015, 51, 2235 DOI: 10.1039/C4CC06165A
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