A reactive probe for Cu2+ based on the ESIPT mechanism and its application in live-cell imaging

Chengyu Yang; Yu Chen; Kai Wu; Tin Wei; Jinglu Wang; Shishen Zhang; Yifeng Han

doi:10.1039/C5AY00224A

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A reactive probe for Cu²⁺ based on the ESIPT mechanism and its application in live-cell imaging†

Chengyu Yang,^a Yu Chen,^a Kai Wu,^a Tin Wei,^a Jinglu Wang,^a Shishen Zhang^a and Yifeng Han*^a

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^a Department of Chemistry, The Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Zhejiang Sci-Tech University, Hangzhou, China
E-mail: zstuchem@gmail.com
Tel: +86-571-86843550

Abstract

A new reactive probe based on an excited-state intramolecular proton transfer (ESIPT) mechanism is reported for the selective detection of Cu²⁺ by the copper induced hydrolysis reaction. The probe is demonstrated to detect Cu²⁺ in living cells.

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Article information

DOI: https://doi.org/10.1039/C5AY00224A
Article type: Communication
Submitted: 26 Jan 2015
Accepted: 15 Mar 2015
First published: 16 Mar 2015

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Anal. Methods, 2015,7, 3327-3330

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A reactive probe for Cu²⁺ based on the ESIPT mechanism and its application in live-cell imaging

C. Yang, Y. Chen, K. Wu, T. Wei, J. Wang, S. Zhang and Y. Han, Anal. Methods, 2015, 7, 3327 DOI: 10.1039/C5AY00224A

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Analytical Methods