Issue 62, 2014
From the journal:

RSC Advances

A highly sensitive TTF-functionalised probe for the determination of physiological thiols and its application in tumor cells†

Wei Wang,*a   Na Zhao,a   Yan Geng,b   Shi-Bin Cui,a   Jürg Hauser,b   Silvio Decurtinsb  and  Shi-Xia Liu*b  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
E-mail: wangwei9612@126.com

b Department of Chemistry and Biochemistry, University of Bern, CH-3012 Bern, Switzerland
E-mail: liu@dcb.unibe.ch

Abstract

A tetrathiafulvalene (TTF)-fused piazselenole as a novel redox-active probe for highly sensitive determination of physiological thiols by electrochemical detection has been synthesised and successfully tested in intracellular non-protein thiol detection, reaching a detection limit of 10−10 M.

Graphical abstract: A highly sensitive TTF-functionalised probe for the determination of physiological thiols and its application in tumor cells

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Article information

DOI
https://doi.org/10.1039/C4RA06455K
Article type
Communication
Submitted
30 Jun 2014
Accepted
21 Jul 2014
First published
21 Jul 2014

RSC Adv., 2014,4, 32639-32642

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A highly sensitive TTF-functionalised probe for the determination of physiological thiols and its application in tumor cells

W. Wang, N. Zhao, Y. Geng, S. Cui, J. Hauser, S. Decurtins and S. Liu, RSC Adv., 2014, 4, 32639 DOI: 10.1039/C4RA06455K

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