Issue 11, 2014
From the journal:

Organic & Biomolecular Chemistry

Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection†

Rajesh K. Pandey,*a   Gregory G. Jarvisa  and  Philip S. Low*a  

* Corresponding authors

a Department of Chemistry, Purdue University, 560 Oval Dr, West Lafayette, IN 47907, USA
E-mail: rkpandey1@yahoo.com, plow@purdue.edu
Tel: +1 765 494 5273

Abstract

The chemical synthesis of staphyloferrin A, a siderophore used by Staphylococcus bacteria for ferric iron retrieval, has been achieved with 79% yield via solid phase peptide synthesis (SPPS). Biological activity of synthetic staphyloferrin A has been confirmed by demonstrating its capture and uptake by live S. aureus.

Graphical abstract: Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection

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Article information

DOI
https://doi.org/10.1039/C3OB41230J
Article type
Communication
Submitted
14 Jun 2013
Accepted
19 Jan 2014
First published
22 Jan 2014

Org. Biomol. Chem., 2014,12, 1707-1710

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Chemical synthesis of staphyloferrin A and its application for Staphylococcus aureus detection

R. K. Pandey, G. G. Jarvis and P. S. Low, Org. Biomol. Chem., 2014, 12, 1707 DOI: 10.1039/C3OB41230J

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