Issue 49, 2014
From the journal:

Chemical Communications

A highly sensitive nucleic acid stain based on amino-modified tetraphenylethene: the influence of configuration†

Li Xu,a   Zece Zhu,a   Xiang Zhou,a   Jingui Qina  and  Chuluo Yang*a  

* Corresponding authors

a Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, Department of Chemistry, Wuhan University, Wuhan, People's Republic of China
E-mail: clyang@whu.edu.cn

Abstract

We designed and synthesized a new amino-functionalized tetraphenylethene (TPE) derivative as a highly sensitive dye for the detection of dsDNA and oligonucleotide in both solution and a gel matrix. We further revealed that the cis configuration dye showed a much higher sensitivity than its trans isomer for the first time.

Graphical abstract: A highly sensitive nucleic acid stain based on amino-modified tetraphenylethene: the influence of configuration

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Article information

DOI
https://doi.org/10.1039/C4CC02671C
Article type
Communication
Submitted
11 Apr 2014
Accepted
01 May 2014
First published
01 May 2014

Chem. Commun., 2014,50, 6494-6497

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A highly sensitive nucleic acid stain based on amino-modified tetraphenylethene: the influence of configuration

L. Xu, Z. Zhu, X. Zhou, J. Qin and C. Yang, Chem. Commun., 2014, 50, 6494 DOI: 10.1039/C4CC02671C

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