Issue 3, 2013

Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues

Abstract

A coumarin-based fluorescence chemoprobe was developed and evaluated for the selective and sensitive detection of hydrogen sulfide in degassed PBS buffers and fetal bovine serum. Fluorescence detection of hydrogen sulfide in living cells was also successfully achieved using two-photon confocal fluorescence imaging. Further in situ visualization of endogenous H2S was realized in cardiac tissues of normal rats and atherosclerosis (AS) rats.

Graphical abstract: Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues

Supplementary files

Article information

Article type
Paper
Submitted
13 Aug 2012
Accepted
30 Nov 2012
First published
30 Nov 2012

Analyst, 2013,138, 946-951

Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues

B. Chen, W. Li, C. Lv, M. Zhao, H. Jin, H. Jin, J. Du, L. Zhang and X. Tang, Analyst, 2013, 138, 946 DOI: 10.1039/C2AN36113B

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